C-10 Flashcards
what would you find in the epidermis
outermost: oil and salt
granulosum: waterproof keratinized skin
spinosum: dendritic cells and karatinocytes
basale: basal cells and melanocytes
what would you find in the dermis
blood vessels
nerve endings
sebaceous glands
hair follicles
what is the tonicity of the skin
hypertonic
components of the normal skin flora
viruses
yeast
gm+ bacteria
virulence
virulence factors help microbes evade the immune system
how would you experimentally determine whether something is a virulence factor
pimple
when the base of a hair follicle
becomes red, swollen, and filled with pus
stye
(staph and eye) AKA hordeolum – when
folliculitis occurs in an eyelash follicle at the base of the eyelid
furuncle
(boil) is a larger, more painful
folliculitis that comes from the spread of the infection into surrounding tissues
carbuncle
is when several furuncles
coalesce, usually in areas of thicker skin (like the back of the neck). Systemic, deeper infectin – triggers fever and chills
reliable way to spot measles
kopek’s spots on oral mucosa
caused by herpes
cold sores
genital herpes
chicken pox
shingles
MMR vaccine
measles
mumps
rubella
- live attenuated and combination vaccine
papillomaviruses causes
warts
good candidate for shingles vaccine
60+ that had chicken pox as a child
disease caused my fungus
mycoses
fungi that cause dermatomycosis
dermatophytes
ringworm
fungus
2 fungi in skin
Candida albicans and malassezia
cutaneous mycoses
direct or indirect contact; or when antibiotics kill normal bacterial flora and allow inhabitants to overgrow
s. aureus
nose
makes coagulase and other enzymes
s. epidermidis
epidermis
disease caused by s. aureus
impetigo
scalded skin syndrome
folliculitis
MRSA
disease caused by s. pyogenes
strep throat
necrotizing facsiitis
impetigo
erysipelas
pseudomonas aeruglnosa makes a green pigment called
pyocyanin; damages host cells with reactive oxygen species
gas gangrene
clostridium perfringens (gm+)
clean wound, debride, aggressive IV antibiotics
most bacteria found in
epidermis along with dendritic cells and dead cells
hair follicles and sebaceous glands found in
dermis
necrotizing diseases
necrotizing fasciitis
gas gangrene
s. aureus
treated with semisynthetic derivative
anti-phagocytic virulence factors
capsule
slime layer
A and M protein
virulence factors that help bacteria invade deeper into the skin
enzymes and toxins
factors that make pseudomonas aeruginosa a problem when treating burn patients
- lots of virulence factors
- ubiquitous
- grow in antiseptics and disinfectants
- thrive in warm and moist environments
