Buxton equations Flashcards by Danielle Hayes | Brainscape

Q

Cl =

A

Vd x kel = 0.693 x Vd / T1/2=dose/auc=kel/Cp

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Q

kel =

A

Cl / Vd

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Q

T1/2=

A

T1/2 = 0.693 x Vd / Cl = 0.693 / kel

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Q

Css =

A

F x D / Cl x dose interval

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Q

Dosing rate =

A

Css x Cl / F

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Q

Maintenance dose =

A

(dosing rate / F) x dosing interval

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Q

Loading dose =

A

Css x Vd / F

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Q

Vd=

A

dose/cp

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