Bronchodilators Flashcards
what do bronchodilators do
relax smooth muscles (prevent contraction)
three ways that respiratory smooth muscle contraction happens
parasympathetic
sympathetic
release of histamines
how does parasympathetic respiratory smooth muscle contraction happen
release acetylcholine
inhibit acetylcholinesterase
how does sympathetic respiratory smooth muscle contraction happen
block beta 2
how does release of histamines smooth muscle contraction happen
H1 receptors
when are cholinergic blockers used for bronchodilators
organophosphate toxicity
which class of bronchodilator also stabilize mast cells and reduce the amount of histamine released
beta 2 adrenergic agonists
when should epinephrine be used as a bronchodilator
in ER situation
what species is clenbuterol used in
horses
what do methylxanthines inhibit
phosphodiesterase (vasoconstriction enzyme)
trivia fact: two other popular human substances that are methylxanthins
caffeine
theobromine (toxic part of chocolate!)