Breast Imaging Flashcards
What makes up the triple assessment of a woman with suspected breast cancer?
Clinical
Radiology = mammography, US
Pathology = image guided core biopsy
How does breast density impact prognosis?
Women with 76-100% density have 4-5x increased risk compared to women with 1-10% density = dense area more predictive than percent dense area
What are the advantages of mammography?
Images whole of both breasts
High sensitivity for DCIS and invasive cancer
Only modality known to reduce population mortality
What are the disadvantages of mammography?
Uses ionising radiation
Can be uncomfortable
What is tomosynthesis?
3D mammography = multiple images from different angles, slices reconstructed, blurs overlapping tissues
What is contrast enhanced spectral mammography?
Identifies contrast enhancement in the breast after IV injection of iodinated contrast material = breast cancers have increased vascularity so enhance
What images can be taken using contrast enhanced spectral mammography?
Low energy image = equivalent to standard 2D DM
High energy image = sensitive to contrast
Subtraction image = only sees lesions that enhance
What is the most important adjunctive imaging modality for breast disease?
US
What are the indications for doing a breast US?
Palpable mass, image guided biopsy, breast inflammation, breast problems during pregnancy, work up of mammographically detected lesion
What are the advantages of US?
No ionising radiation and not uncomfortable for patient
Good sensitivity and specificity for invasive cancer
Can differentiate cystic from solid
Quick if examination tailored to specific area
Cheap and image guided biopsy very easy
What are the disadvantages of US?
Low specificity when used for screening
Low sensitivity for DCIS
What are some advanced US techniques?
Strain elastography, shear wave elastography, contrast enhanced US, 3D US
What are some features of contrast enhanced US?
Allows quantitative assessment of perfusion
2D or 3D
What are some uses of contrast enhanced US?
Assessing response to NACT
Axillary node characterisation
Improving BIRADS of solid breast masses
What does elastography measure?
Differences in tissue firmness