Breast Flashcards
What is a risk assessment tool that calculates invasive CA risk in the next 5 years and overall risk? Focussed on first degree relatives
Gail model
What risk assessment tool incorporates 1st and 2nd degree male and female relatives and family members w/ ovarian CA. No personal/ lifestyle risks.
Claus model
What is a model that is given for high risk women in a given family? It maps out mutation frequencies, penetration/ affected carriers. Age of onset: 1st and 2nd degree male and female relatives
RBCAPRO model
What is the primary node that drains the area from around the breast? This is usually tested during a mastectomy.
Sentinel node
When is the ideal time for the BSE to be performed?
5-7 days after onset on menses
When is nipple discharge considered abnormal?
If occurs >6 months after cessation of breast feeding
How often should a CBE be done for women 20-39?
Every 1-3 years
How often should CBE be done for women over 40?
Annually
When should mammograms be done according to ACOG, AMA, and ACS?
Annually >40 years old
When does USPSTF believe mammography should be given?
every 2 years from 50-74 y/o
ER positive cancer means what?
Estrogen receptor positive
According to ACS when should a women get a MRI?
Known lifetime risk >20%
BRCA mutation (or 1st degree relative with)
Chest radiation (ages 10-20)
patient with 1st degree relative has high risk genetic cancer
Known risk 15-20%
Breast CA, LCIS< DCIS atypical hyperplasia
Dense/ uneven breasts
A women who had ER positive cancer can use this drug for chemoprevention in post cancer.
SERMs
What are two types of SERMs?
Thamoxifen
Raloxifene
What are some side effects of SERMs?
Endometrial Ca
thromboembolic events
Cataracts
What SERM is for post-menopausal women and has less side effects?
Raloxifene