Breast Flashcards

1
Q

What is a risk assessment tool that calculates invasive CA risk in the next 5 years and overall risk? Focussed on first degree relatives

A

Gail model

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2
Q

What risk assessment tool incorporates 1st and 2nd degree male and female relatives and family members w/ ovarian CA. No personal/ lifestyle risks.

A

Claus model

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3
Q

What is a model that is given for high risk women in a given family? It maps out mutation frequencies, penetration/ affected carriers. Age of onset: 1st and 2nd degree male and female relatives

A

RBCAPRO model

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4
Q

What is the primary node that drains the area from around the breast? This is usually tested during a mastectomy.

A

Sentinel node

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5
Q

When is the ideal time for the BSE to be performed?

A

5-7 days after onset on menses

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6
Q

When is nipple discharge considered abnormal?

A

If occurs >6 months after cessation of breast feeding

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7
Q

How often should a CBE be done for women 20-39?

A

Every 1-3 years

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8
Q

How often should CBE be done for women over 40?

A

Annually

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9
Q

When should mammograms be done according to ACOG, AMA, and ACS?

A

Annually >40 years old

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10
Q

When does USPSTF believe mammography should be given?

A

every 2 years from 50-74 y/o

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11
Q

ER positive cancer means what?

A

Estrogen receptor positive

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12
Q

According to ACS when should a women get a MRI?

A

Known lifetime risk >20%
BRCA mutation (or 1st degree relative with)
Chest radiation (ages 10-20)
patient with 1st degree relative has high risk genetic cancer
Known risk 15-20%
Breast CA, LCIS< DCIS atypical hyperplasia
Dense/ uneven breasts

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13
Q

A women who had ER positive cancer can use this drug for chemoprevention in post cancer.

A

SERMs

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14
Q

What are two types of SERMs?

A

Thamoxifen

Raloxifene

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15
Q

What are some side effects of SERMs?

A

Endometrial Ca
thromboembolic events
Cataracts

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16
Q

What SERM is for post-menopausal women and has less side effects?

A

Raloxifene

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17
Q

What’s the first question to ask?

A

Do you have any breast concerns/ issues today?

18
Q

Green nipple discharge can indicate what?

A

Fibrocystic changes

19
Q

Are breast cancers usually tender or non-tender?

A

Non-tender

20
Q

What shape is not reassuring in a breast exam?

A

Irregular

21
Q

Is it better for a mass to move or fixed?

A

Move

22
Q

What consistency indicates a non-cancerous mass?

A

Smooth, rubbery,

23
Q

What is usually found in pre menopausal women, well defined, round, mobile. No skin retraction. Non-proliferative

A

Cyst

24
Q

What is a discrete, round, firm, mobile & nontender, solitary. No skin retraction, reproductive years usually.

A

Fibroadenoma

25
Q

What are 3 types of proliferative lesions without atypia?

A
  • intraductal papillomas
  • epithelial hyperplasia
  • sclerosing adenosis
26
Q

What are the 2 types of proliferative lesions with atypia?

A

LCIS

DCIS

27
Q

This type mass is very mobile, well delineated, may be soft or firm, is round, disclike or lobular and is usually found in young adults.

A

Fibroadenoma

28
Q

This type of breast mass are round and soft to firm, usually elastic. They are well delineated and mobile and often tender. Usually found in women 30-50.

A

Breast cyst

29
Q

This breast is most commonly found in women over 50. Has an irregular or stellate shape and is firm or hard. Not clearly delineated and may be fixed to skin or underlying tissues. Retraction may be present.

A

Cancer

30
Q

Which type breast cyst is often tender?

A

Cyst

31
Q

What does edema of the skin of the brast indicate?What is a name for this

A

Produced by a lymphatic blockade

Called peau d’orange sign

32
Q

What type of brast cancer starts as a scaly eczemalike lesion that may weep, crust, or erode. Breast mass may be present. Suspect this with any persisting dermatitis of the nipple and areola.

A

Paget’s Disease of the Nipple

33
Q

What does spontaneous unilateral bloody discharge from one or two ducts of the nipple suggest?

A

Intraductal papilloma
Ductal carcinoma in situ
Paget’s disease of the breast

34
Q

What is nonpuerperal galactorrhea?

A

Milky discharge unrelated to a prior pregnancy.

35
Q

What are SERMs?

A

Selective estrogen receptor modulators

36
Q

What are 2 SERMs?

A

Tamoxifen and raloxifene

37
Q

Who is raloxifene approved for?

A

Post menopausal women

38
Q

When is the best time to do a clinical breast exam?

A

5 to 7 days after the onset of menses

39
Q

This arises from an imbalance of estrogens and androgens in males sometimes drug related.

A

Gynecomastia

40
Q

What is the name for a sweat gland infection?

A

Hidradenitis syuppurativa