brain control of movement Flashcards

1
Q

top-down motor control

A

The brain controls both voluntary and

involuntary movements

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2
Q

Axons from Motor Cortex (M1) descend along 2 major pathways, which are…

A
  • Lateral

- Ventromedial

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3
Q

Lateral Pathways subsets

A

Corticospinal
-ipsilateral
(human-specific)

Rubrospinal tract
-contralateral
(older structure)

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4
Q

Corticospinal ipsilateral or counterlateral

A

ipsilateral

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5
Q

Rubrospinal tract ipsilateral or counterlateral

A

counterlateral

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6
Q

Vestibulospinal helps with

A
  • eyes stable

- upright balance

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7
Q

tectospinal tract helps….

A

up.
colliculus orient
head, trunk,
shoulders

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8
Q

Humonculous:

A

distorted map of muscles of the contralateral side

Located at posterior end of Frontal lobe

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9
Q

what codes the direction of movement:

A

motor cortex

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10
Q

Donoghue & Sanes at Brown University

A

mapped motor nerves that controlled whisker
movements (purple), then lesioned some. The Motor map reorganized to later
controlling the forelimb (red) and eye movements (yellow)

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11
Q

why does phantom limb pain happen

A

needs

feedback of unclamped hand

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12
Q

Planning & Executing Complex Movements steps

A

Prefrontal (strategic) > Supplemental (tactical) > Premotor
(sequence) >
M1 (activation)

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13
Q

Weinrich and Wise found that …

A
some neurons in an area of
macaque monkeys' area 6 cortex
(SMA, PMA) fire when the
monkeys planned to do things
like reach for or bite a peanut.
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14
Q

Apraxia

A
inability to
perform complex (but not simple) movements -
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15
Q

what results in apraxia

A

Lesions in Supplemental Motor Area

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16
Q

mirror neurons

A
Premotor and
Supplementary Motor
Areas fired similarly
when they simply
observed the (intention)
of the same action
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17
Q

mirror neurons are sensitive to …

A

intention of movement

they will fire even when the end behavior is blocked:

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18
Q

what does basil ganglia control

A

force of movements

19
Q

what does cerebellum control

A

accuracy

20
Q

two basil ganglia diseases

A
Hypo kinesia (-)
e.g Parkinson’s
Hyper kinesia (+)
e.g. Huntington’s Chorea
21
Q

Hypo kinesia

A

parkinsons

22
Q

hyper kinesia

A

huntingtons chorea

23
Q

Parkinson’s results in

A

3-5Hz resting tremor

24
Q

Huntington’s Chorea

A
coordinated movements
Cerebellar damage (ataxia) results in intention tremor
25
Q

alleviate Basal Ganglia

symptoms in Tourette’s Syndrome

A

Deep Brain Stimulation

26
Q

Where do feedback loops go to

A

Basil ganglia and cerebellum

27
Q

What are the two major pathways that go down from M1

A

Lateral

Ventromedial

28
Q

Reciprocal inhibition

A

Contrast of one set of muscles accompanied by the relaxation of their antagonistic muscles

29
Q

Golgi tendon organ

A

Acts like sensitive strain gauge

Modulates muscle tension and forces contraction

Located at junction of muscle and tendon

30
Q

What are Golgi tendon organs innervated by

A

1b sensory axons

These axons the. Enter spinal cord and synapse at 1b inhibitory interneurons in the centeral horn

31
Q

How does the muscle protect itself from being overloaded

A

Golgi modulates muscle tension by activating 1b sensory axons

1b interneurons from inhibitory connections with alpha motor neurons that innervate the same muscle

32
Q

Where does most input to alpha neurons com from

A

Interneurons of spinal cord

33
Q

Where are most interneurons found

A

Grey column

34
Q

Interneuron function

A

Create neural circuits, enabling communication between sensory and motor neurons

Help with reflexes

35
Q

1a axons

A

Detect changes in muscle length

36
Q

Propreoceptors

A

a sensory receptor which receives stimuli from within the body, especially one that responds to position and movement.

37
Q

Proreception

A

How our body is positioned and moving in space

38
Q

Monosynaptic stretch reflex

A

Between alpha motor and 1a axon

Called monosynaptic because only one synapse separates primary sensory input from motor neuron output

Stretching depolarizers mechanoreceptors and causes muscle to shorten

39
Q

The purpose of interneurons

A

They help reflexes

Some are excitatory and some are inhibitory

40
Q

Excitatory reflex

A

Flexor withdrawal reflex

Withdrawal from aversive stimulus

41
Q

Circuits that give rise to rhythmic motor activity

A

Central pattern generators

42
Q

Crossed extensor reflex

A

Another excitatory reflex

It’s when activation of extensor muscles on opposite side of pain. This puts more weight on the other limb so the limb with pain can withdrawal

43
Q

Premotor vs supplemental

A

premotor cortex-selecting motor programs based on visual stimuli or on abstract associations

supplementary motor area- selecting movements based on remembered sequences of movements.

44
Q

Steps for movement

A

Visual input
Frontal lobe motor area plans
Spinal cord carry info to ___
Motor neurons carry message from___

Sensory receptors on fingers send message to cortex saying that goal has been met