Bovine metabolic disease Flashcards

1
Q

Name the possible types of post-calving metabolic disease to occur in cows

A
milk fever
RFM
metritis
endometritis
DA (left or otherwise)
ketosis
fat metabolism syndrome
fertility issues
lameness
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2
Q

as with anything with cows - what are the major RF for any metabolic dz

A

reduced DMI
NEB
immunosuppression

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3
Q

what actually is MILK FEVER

A

hypOcal

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4
Q

what are the clinical sign of milk fever

A
recumbent (characteristic S-bend)
hyper-excitation
tremor
NO POO (lack of motility)
dry noses
\+- bloat (recumbent, no eructation)
slow HR and pulses
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5
Q

wha re some other common ddx for milk fever

A

e coli mastitis (endotoxaemic BUT no d++ or high HR!)
botulism
salmonellosis
calving intervals - nerve damage or femoral head lig damage

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6
Q

how can you tx milk fever/

A
Ca borogluconate (40%) iv SLOWLY IV if shes recumbent
AND foston for ANY hypoPO4 (wont harm if nto)
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7
Q

when is hypocal likely to be seen in sheep``

A

pre-lambing or high stress

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8
Q

how can you try and prevent milk fever?

A

encourage PTH release BEFORE Ca is needed:

  • feed low Ca++ diet
  • feed high Mg
  • Ca bolus at carving
  • encourage maximum DMI PRE-calving
  • feed high K+ (grass silage!)
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9
Q

other than the metabolic effects of milk fever - what other considerations must be made?

A

myopathy wi 24hrs being recumbant

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10
Q

after how long of a cow being recumbent does the px really decrease??

A

72hrs - probs wont ever stand

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11
Q

how often should you shift a recumbent cow

A

q 3hrly

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12
Q

how many mg of Ca is in 1L of colostrum

A

2.3mg of Ca / L of colostrum

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13
Q

why does hypoMg have anything to do with milk fever>

A

Mg is required to help intestinal absorption of Ca++

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14
Q

what does PTH do

A

inc Ca release
inc Oclasts
helps abs

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15
Q

how does acid:base balance effects the likelihood of getting milk fever

A

Ca is bound to albumin - this is reduced by low pH

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16
Q

whats Ca actually needed for?

A

muscle fct ALL types
nerve impulses
immune responses
…..

17
Q

when might hypophosphateaemia occur in its own right?

A

peri-parturient haemogloburia

18
Q

after a downer cow has been given calcium, and it still wont rise - what else could you try

A

give foston I/v (Phosphate) as may be hypoPO4 too

19
Q

is milk fever always clinically obv

A

no - subclinical too = RF for other diseases (mastitis, immune suppression, metritis…)

20
Q

whatis grass staggers

21
Q

how do you treat hypoMg

A

be quiet
control convulsions - xylazine
give Ca borogluc slowly AND then magnesium iv

22
Q

what are the signs of hypomag

A

death
convulsions + recumbent
hypersensitive + twitchy = early signs

23
Q

what causes hypoMg

A

theres no body reserves - all from diet
7L of milk takes the entire plasma vlume of mg
lush pastures
fertilised pasture as these have high K, which prev abs of Mg

24
Q

how can you prevent hypomag

A
bolus
licks
supplement feed
sprinkle over food
change pasture
give straw to slow GI transit time
25
regarding ketosis and fat mobilisation syndrome.... which VFA goe to prod glucose by reacting with oxalo-acatate ?
proprionate
26
where do the other 2 VFAs go to help produce glucose
to acetyl co a
27
lipolysis releases why from the fat reserves for E
NEFAs and glycerol
28
whichVFA is basically 'in charge' of glucose prod via gluconeogenesis
proprionate - as its needed to make oxalo-acatate
29
why are ketones bodies no good for brain and milk prod
cant be used in nervous system for E, or for making lactose | only used in muscle for E
30
what are the clinical signs of ketosis
``` red milk yeidl selective anorexia (don't like conc) ketonaemia shiny poo poss presentation = 'nervous ketosis' ```
31
what does nervoud ketosis look like
``` hyper-excitable twitchy maniacal licking bellowing aggression ```
32
what are the ddx which you might be concerned about for nervous ketosis
BSE hypoMag Listeriosis
33
how do you treat ketosis
oral propylene glycol csteroids glucose 40% iv vit B12
34
how do you diagnose sub-clinical ketosis
BOHB in blood -target is <10% of the '@ risk' cows are below 1.4mml/L blood NEFA - check in 2wks BEFORE calving. aim for <0.4mmol/L
35
how can herd level sub clin ketosis be monitored?
milk :online monthly recording of yield, BF, MP and SCC kg loss: NEB, ketone level and NEFA, high BF%
36
to monitor kg loss, and to target nutrition, when should you BCS cows
100 d BEFORE dry-off, then you can aim to get them to 2.5 by dry period