Bood Test Prep Flashcards
How much blood is in a person
4-6 litres
What is blood made of
55% plasma (liquid)
45% formed elements
Leukocyte (going in bone marrow)
Erythrocytes (found in bone marrow)
Erythrocytes
99% blood cells Biconcave disk Red blood cells 8.5 um Full of hemoglobin (transports O2/CO2) Small round smooth large surface area Enucleate (no nucleus) Lives for 120 days Produced in bone marrow Removed from blood by the liver (produces bile from them)
Leukocyte
White blood cell Internal defence system Most not inside blood vessels Found in ECF and the lymphatic system Differ in shape of nucleus
How do leukocytes destroy antigens
Eat, histamines, produce anibodies
What are antigens
Things that don’t belong
What are histamines
Small proteins that cause blood vessels in the area to dilate
What are antibodies
Specific proteins to target specific antigens
What determines the type of blood by protein
Identifies proteins on the surface of RBC (antigens)
Antibodies found in the blood plasma
In a transfusion what do you need to consider
What will happen to the donated RBCs
If blood is forced together that do not match,
Blood cells will clump together
What is the Rhesus factor(Rh)
Another protein that can be found of surface if RBCs (antigens)
Rh+
(85%)
Do have Rh antigen
Do not make Rh antibodies
Can receive from both Rh+ and Rh- blood
Rh-
(15%)
Do not make Rh antigen
Can make Rh antibodies but only after exposure to Rh+ blood
Can receive Rh+ blood one time only
Fetal Erythroblastosis
Can occur if a Rh- mother has more than one Rh+ pregnancies
1) placenta prevents Rh+ blood cells from entering Mom
Mom does not make Rh antibodies
During after birth fetal blood mixes with moms blood
Mom makes Rh antibodies
2) once placenta develops moms antibodies cross into fetal blood
Fetal blood destroyed (miscarriage)
Prevention of fetal Erythroblastosis
At first birth mother is injected with RHO Gom which prevents antibody formation