Bood Test Prep Flashcards

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1
Q

How much blood is in a person

A

4-6 litres

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2
Q

What is blood made of

A

55% plasma (liquid)
45% formed elements
Leukocyte (going in bone marrow)
Erythrocytes (found in bone marrow)

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3
Q

Erythrocytes

A
99% blood cells
Biconcave disk
Red blood cells
8.5 um
Full of hemoglobin (transports O2/CO2)
Small round smooth large surface area
Enucleate (no nucleus)
Lives for 120 days
Produced in bone marrow 
Removed from blood by the liver (produces bile from them)
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4
Q

Leukocyte

A
White blood cell
Internal defence system
Most not inside blood vessels
Found in ECF and the lymphatic system
Differ in shape of nucleus
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5
Q

How do leukocytes destroy antigens

A

Eat, histamines, produce anibodies

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6
Q

What are antigens

A

Things that don’t belong

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7
Q

What are histamines

A

Small proteins that cause blood vessels in the area to dilate

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8
Q

What are antibodies

A

Specific proteins to target specific antigens

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9
Q

What determines the type of blood by protein

A

Identifies proteins on the surface of RBC (antigens)

Antibodies found in the blood plasma

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10
Q

In a transfusion what do you need to consider

A

What will happen to the donated RBCs

If blood is forced together that do not match,
Blood cells will clump together

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11
Q

What is the Rhesus factor(Rh)

A

Another protein that can be found of surface if RBCs (antigens)

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12
Q

Rh+

A

(85%)
Do have Rh antigen
Do not make Rh antibodies
Can receive from both Rh+ and Rh- blood

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13
Q

Rh-

A

(15%)
Do not make Rh antigen
Can make Rh antibodies but only after exposure to Rh+ blood
Can receive Rh+ blood one time only

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14
Q

Fetal Erythroblastosis

A

Can occur if a Rh- mother has more than one Rh+ pregnancies
1) placenta prevents Rh+ blood cells from entering Mom
Mom does not make Rh antibodies
During after birth fetal blood mixes with moms blood
Mom makes Rh antibodies
2) once placenta develops moms antibodies cross into fetal blood
Fetal blood destroyed (miscarriage)

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15
Q

Prevention of fetal Erythroblastosis

A

At first birth mother is injected with RHO Gom which prevents antibody formation

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16
Q

What is blood plasma made of

A

(92%) water
(7-8%) blood proteins (albumin, fibrinogen, antibodies)
(1%) salts (electrolytes)
(Other less than 1%)
-digestive foods (glucose), gases (O2/CO2), hormones, waste products (ammonium)

17
Q

Function and source of water in blood protein

A

Temperature regulation
Solvent transports molecules (glucose, hormones, carbon dioxide etc.)
Makes up a big part of blood volume (B.P.)

Metabolism (dehydration synthesis)
Digestive system

18
Q

Blood proteins in blood plasma

A
Maintains osmotic pressure
Forms blood clots
Body defence (immunity) antigens attack antibodies

Albumin, fibrinogen— liver
Antibodies— lymphocytes

19
Q

Salts in blood plasma

A

Osmotic pressure
pH control of blood
Various metabolic functions (ex: Ca=blood clot)

Digestive system

20
Q

Other in blood plasma

A

Various functions

Various sources

21
Q

Blood clotting

A

When blood vessels are broken they must be plugged to prevent excessive blood loss

Blood clotting is a complex “Cascade” of reactions

22
Q

What is T.P.A.

A

Tissue plasminogen agent

TPA dissolves clot after outer surface recovers 2-3 days later

23
Q

Capillary/Tissue Fluid Exchange

A

Molecules exchanged between blood and ECF at the capillaries
Diffusion plays a large role
Two other forces are involved in moving molecules in/out of capillaries
Blood pressure
Osmotic pressure

24
Q

What is blood pressure and osmotic pressure in Capillary/Tissue Exchange

A

Blood pressure.
Squeezes molecules out of blood into ECF

Osmotic pressure.
Diffusion of water (and other dissolved molecules) moves fluid into capillaries

25
Q

During capillary/Tissue fluid exchange what goes in a cell

A

In
O2
Glucose

Out
CO2
NH3

26
Q

What is the change in blood pressure and osmotic pressure during capillary/Tissue fluid exchange

A

Start
BP (40mmHg)
-OP(25mmHg)=
15mmHg out

End
OP (25mmHg)
-BP(11mmHg)=
14 mmHg in

27
Q

How much is lost to the lymphatic system during capillary/Tissue fluid exchange

A

1/10th

28
Q

What is the lymphatic system

A

An alternate system for returning fluid to heart

Composed of:
Lymph capillaries
Lymph veins (end at Subclavian veins)
Lymph nodes (full of white blood cells that fight bacteria)