Bood Test Prep Flashcards
How much blood is in a person
4-6 litres
What is blood made of
55% plasma (liquid)
45% formed elements
Leukocyte (going in bone marrow)
Erythrocytes (found in bone marrow)
Erythrocytes
99% blood cells Biconcave disk Red blood cells 8.5 um Full of hemoglobin (transports O2/CO2) Small round smooth large surface area Enucleate (no nucleus) Lives for 120 days Produced in bone marrow Removed from blood by the liver (produces bile from them)
Leukocyte
White blood cell Internal defence system Most not inside blood vessels Found in ECF and the lymphatic system Differ in shape of nucleus
How do leukocytes destroy antigens
Eat, histamines, produce anibodies
What are antigens
Things that don’t belong
What are histamines
Small proteins that cause blood vessels in the area to dilate
What are antibodies
Specific proteins to target specific antigens
What determines the type of blood by protein
Identifies proteins on the surface of RBC (antigens)
Antibodies found in the blood plasma
In a transfusion what do you need to consider
What will happen to the donated RBCs
If blood is forced together that do not match,
Blood cells will clump together
What is the Rhesus factor(Rh)
Another protein that can be found of surface if RBCs (antigens)
Rh+
(85%)
Do have Rh antigen
Do not make Rh antibodies
Can receive from both Rh+ and Rh- blood
Rh-
(15%)
Do not make Rh antigen
Can make Rh antibodies but only after exposure to Rh+ blood
Can receive Rh+ blood one time only
Fetal Erythroblastosis
Can occur if a Rh- mother has more than one Rh+ pregnancies
1) placenta prevents Rh+ blood cells from entering Mom
Mom does not make Rh antibodies
During after birth fetal blood mixes with moms blood
Mom makes Rh antibodies
2) once placenta develops moms antibodies cross into fetal blood
Fetal blood destroyed (miscarriage)
Prevention of fetal Erythroblastosis
At first birth mother is injected with RHO Gom which prevents antibody formation
What is blood plasma made of
(92%) water
(7-8%) blood proteins (albumin, fibrinogen, antibodies)
(1%) salts (electrolytes)
(Other less than 1%)
-digestive foods (glucose), gases (O2/CO2), hormones, waste products (ammonium)
Function and source of water in blood protein
Temperature regulation
Solvent transports molecules (glucose, hormones, carbon dioxide etc.)
Makes up a big part of blood volume (B.P.)
Metabolism (dehydration synthesis)
Digestive system
Blood proteins in blood plasma
Maintains osmotic pressure Forms blood clots Body defence (immunity) antigens attack antibodies
Albumin, fibrinogen— liver
Antibodies— lymphocytes
Salts in blood plasma
Osmotic pressure
pH control of blood
Various metabolic functions (ex: Ca=blood clot)
Digestive system
Other in blood plasma
Various functions
Various sources
Blood clotting
When blood vessels are broken they must be plugged to prevent excessive blood loss
Blood clotting is a complex “Cascade” of reactions
What is T.P.A.
Tissue plasminogen agent
TPA dissolves clot after outer surface recovers 2-3 days later
Capillary/Tissue Fluid Exchange
Molecules exchanged between blood and ECF at the capillaries
Diffusion plays a large role
Two other forces are involved in moving molecules in/out of capillaries
Blood pressure
Osmotic pressure
What is blood pressure and osmotic pressure in Capillary/Tissue Exchange
Blood pressure.
Squeezes molecules out of blood into ECF
Osmotic pressure.
Diffusion of water (and other dissolved molecules) moves fluid into capillaries