Bone - nutritional, toxic, neoplastic Flashcards
what is the main cause of osteoporosis
nutritional/starvation
what clinical signs do you see with osteoporosis
decreased quantity of bone
fracture without excessive trauma
increase incidence in fractures
porous bone
can get serous atrophy of fat
what is the difference between rickets and osteomalacia
both defect in mineralization due to nutritional abnormalities (vitamin D or P)
rickets - young animals, growth plate and bone
osteomalacia - adults, bone only
causes of rickets and osteomalacia
nutritional
vit D - esp sheep thick coats
P - lead to osteophagia
hereditary
clinical sign of rickets and osteomalacia
lameness
due to decrease quality and quantity of bone
causes of fibrous osteodystrophy
driven by PTH (decrease Ca)
low Ca, high P diet
(high grain diets)
renal
clinical signs of fibrous osteodystrophy
rubbery bones
fibrous replacement in skull
fractures, deformities, normal physes
lesions of scurvy
oral & periosteum/periarticular hemorrhage
no osteoid
cause of scurvy
what species is this common in and why?
vitamin C deficiency
guinea pigs due to lack of L-gulonolactone oxidase
lesions associated with fluoride toxicity
chalky opaque bone
black teeth discoloration
periosteal hyperostosis
brittle bone
enamel hypoplasia
osteoma
behavior
flat bones of head, rostral mandible, oral cavity
osteosarcoma
predilection
age
behavior
large breed dogs 7.5 yr, older cats
appendicular > axial, does NOT cross the joint
-shoulder, carpus, stifle
very aggressive
chondrosarcoma
predilection
behavior
all species
flat bones, appendicular, joints, soft tissue - does NOT cross the joint
multilobular tumor of bone
predilection
behavior
dog, horse, cat
flat bone of skull
local disease
fibrosarcoma
predilection
behavior
all species
periosteal/medulla of all bones
better prognosis
