Bone development pt 2

Question 1

bone tissue
formation

Answer 1

Osteogenesis (ossification)

Question 1

What are the stages of Osteogenesis?

Answer 1

Bone formation = begins in the 2nd month of
development

Postnatal bone growth = until early adulthood

Bone remodeling and repair = occurs lifelong

Question 2

Two Types of Ossification

Answer 2

Intramembranous
Endochondral

Question 3

Forms flat bones, e.g. clavicles and cranial
bones

Answer 3

Intramembranous

Question 4

Cartilage (endochondral) bone forms by replacing hyaline cartilage
Forms most of the rest of the skeleton

Answer 4

Endochondral

Question 5

Uses hyaline cartilage models
•Requires breakdown of hyaline cartilage prior
to ossification

Answer 5

Endochondral Ossification

Question 6

length of long bones occurs at the
epiphyseal plate

Answer 6

Interstitial growth

Question 7

thickness and remodeling of all bones by
osteoblasts and osteoclasts at the periosteum

Answer 7

Appositional growth

Question 8

Epiphyseal plate cartilage organizes into four important functional zones:

Answer 8

1. Proliferation (growth) = cells increase in number
2. Hypertrophic = cells increase in size
3. Calcification = Matrix becomes calcified; cartilage cells die; matrix begins deteriorating
4. Ossification (osteogenic) = New bone formation is occurring

Answer 9

Osteoclasfg sjlrbg jsr gL GjLR GJLSRm dfts secrete g

Question 10

Occurs where bone is injured or added strength
is needed

Answer 10

Occurs where bone is injured or added strength
is needed

Question 11

Occurs where bone is injured or added strength is needed

Answer 11

Bone deposit

Question 12

Lysosomal enzymes (digest organic matrix)
• Acids (convert calcium salts into soluble 
forms)

Answer 12

Bone resoption