Body Fluids And Circulation Flashcards
All living cells have to be provided with ____,____and ____.
Nutrients
O2
Other essential substances
Simple organisms like ____and ___ circulate water from the surroundings through their body cavities to facilitate the cells to exchange these essential substances .
Sponges
Coelenterates
_use special fluids to transport such. Essential materials .
More complex organisms
___is the most commonly used body fluid .
Blood
Tissue fluid -
Lymph
Blood 🩸 is a ____tissue consisting of _,__and ____.
Fluid matrix
Plasma
Formed elements
Plasma is a __coloured , _____fluid
Straw-coloured
Viscous
Plasma constitutes nearly ___%of the blood .
55%
Water constitutes ___% of plasma .
90-92%
Proteins contribute __ % of plasma .
6-8%
What are the major proteins found in PLASMA -
3
Fibrinogens
Globulins
Albumins
Constituents of plasma -
Water -90-92% Proteins -6-8% Minerals -small amounts Glucose Among acids Lipids
_____are needed for clotting or coagulation of blood .
Fibrinogens
____are involved in the defence mechanism of the body .
Globulins ( part of proteins in plasma )
____ help in OSMOTIC BALANCE .
Albumins ( part of proteins in plasma )
Plasma also contains small amounts of minerals like -
Na+ Ca++ Mg++ HCO3- Cl-
_,__and__are also present in plasma AS THEY ARE ALWAYS IN TRANSIT IN THE BODY .
Glucose
Amino acids
Lipids
Factors for __or ___of blood are also present in the plasma .
Clotting
Coagulation
Factors for coagulation or clotting of blood are also present in the plasma in an __form .
Inactive
______ without _____is called SERUM .
Plasma
Clotting factors
__,____and ____are collectively called formed elements .
Erythrocytes
Leukocytes
Platelets
Formed elements constitute nearly ____% of the blood .
45%
_are the most abundant of all the cells in the blood 🩸
RBCs / erythrocytes
A healthy adult person on an average has ___RBCs mm-3 of blood 🩸.
5 -5.5 million mm-3
RBCs are formed in the ____ in the adults
Bone marrow
RBCs are devoid of nucleus in most of the ___and are ____in shape .
Mammals
Biconcave
RBCs have a red -coloured ,____containing ___ called _____.hence the colour and name of these cells .
Iron
Complex protein
Haemoglobin
A healthy individual has ______ of Hb in every 100ml of BLOOD 🩸.
12-16 gms
These molecules play a significant role in transport of respiratory gases - which ?
Hb molecules
RBCs have an average life-span of -
120 days
After 120 days ,RBCs are destroyed in the _____.
Spleen -graveyard of the RBCs
__Are also called WBCs as they are ______
Leucocytes
Colourless
WBCs are colourless due to -
Lack of Hb
WBCs are ______and ______in number (unlike RBCs )
Nucleated
Relatively Lesser
No of WBCs averages _______mm-3 of blood 🩸
6000-8000 mm-3
Leucocytes are generally _____lived .
Short
Categories of WBCs -
Granulocytes
Agranulocytes
How many types of WBCs come under GRANULOCYTES -name
3
Neutrophils
Eosinophils
Basophils
How many WBCs come under AGRANULOCYTES -
2
Lymphocytes
Monocytes
______are the most abundant cells of the total WBCs . They comprise __% of WBCs .
Neutrophils
60-65%
__Are the least abundant . They comprise __% of the total WBCs .
Basophils
0.5-1%
Monocytes comprise ____% of WBCs .
6-8%
Eosinophils comprise __% of WBCs .
2-3%
Lymphocytes comprise _% of WBCs .
20-25%
____and _____are PHAGOCYTIC cells which destroy foreign organisms entering the body .
Neutrophils
Monocytes
____are involved in INFLAMMATORY reactions
Basophils
Basophils secrete ____,____and_____.
Histamine
Serotonin
Heparin
(Involved in inflammatory rxns )
___Are associated with ALLERGIC rxns (among WBCs )
Eosinophils
Eosinophils resist ____and are associated with _____.
Infections
Allergic rxns
Lymphocytes are of how many types ? What is their function?
2 - T and B
Responsible for immune responses of the body
Name 2 blood groupings -
ABO
Rh
ABO grouping is based on the presence or absence of _______on the RBCs .
2 surface ANTIGENS -A and B
What are ANTIGENS ?
Chemicals that can induce immune response .
Present on the surface of RBCs
____of different individuals contain 2 natural ANTIBODIES .
Plasma
Antibodies are proteins produced in response to ____ .
Antigens
Antibodies-present in the plasma
Name the antibodies and antigens -
Antibodies -anti A ,anti B ,anti AB ,nil
Antigens -A , B ,AB ,nil
(O is neither an antigen nor any antibody , its a blood group )
During transfusions , blood of the donor must match the blood of the recipient to avoid -
Severe problems of clumping (destruction of RBCs )
For blood transfusions ,__is checked .
Donor’s compatibility
Blood grp O has which ANTIGEN and which ANTIBODY ?
Antigen on RBC -nil
Antibody in plasma -anti-A,B
Blood grp AB has which antigen and which antibody ?
Antigen on RBC - A ,B
Antibody in plasma - nil
What should be the donor’s grp for blood grp B ?
B
O
____is universal donor .
O -ve
____is universal acceptor /recipients .
AB +ve
Another ____ , similar to the one present in rhesus monkey is also observed on ______ of humans .
Antigen -Rh antigen
On the surface of RBCs
Rh antigen is present on the surface of RBCs of _____% of humans .
Nearly 80%
majority
What are the individuals called in which Rh antigen is absent -
Rh -ve
Rh group should also be matched before transfusions ,T/F
T
An Rh -ve person if exposed to Rh+ve blood will form -
Specific antibodies against the Rh antigen
A special case of Rh incompatibility has been observed btw the Rh-ve blood of ______ with Rh+ve blood of _____.
Pregnant mother
Foetus
Rh antigens of the foetus do not get exposed to the Rh-ve blood of the mother in the ____pregnancy becoz -
1st
The 2 bloods are well-separated by the placenta
During the delivery of the _____ child ,there is possibility of exposure of the maternal blood to small amounts of ____blood from the ___.
1st
Rh +ve
Foetus
If the maternal blood is exposed to small amounts of Rh-ve blood of blood during delivery of 1st child , what happens then ?
Mother (maternal blood )starts preparing ANTIBODIES against Rh (+ve) ANTIGENS in her blood .
In case of subsequent pregnancies , the ___ from the mother can leak into the blood of the foetus and destroy the FOETAL RBCs .
Rh antibodies ( which were formed earlier ) If the foetus is Rh+ve , then antibodies ( which were formed against Rh+ve )destroy these Rh+ve RBCs of blood
Rh incompatibility in case of Rh-ve mother and Rh+ve child can be __to the foetus and can cause _____and ______to the baby .
Fatal
Severe anaemia
Jaundice
Severe anaemia and jaundice to the baby in case of Rh incompatibility is called -
Erythroblastosis foetalis
Erythroblastosis foetalis can be avoided by administering ___to ____ after _____.
Anti-Rh antibodies
Mother
Immediately after delivery of 1st child
Blood exhibits _____or _____ in response to injury or trauma .
Coagulation
Clotting
Coagulation or clotting is the mechanism to avoid _____.
Excessive loss of blood from the body
The dark reddish brown sum formed at the site of a cut or an injury over a period of time is a ___or ____ formed mainly of a network of THREADS called ______.
Clot
Coagulam
Fibrins
In fibrins , ___are trapped .
Dead and damaged formed elements of blood 🩸
Fibrins are formed by the conversion of ___in the ___by the enzyme _____.
Inactive fibrinogens
Plasma
Thrombin
Fibrinogens are present in the plasma is an ______state .
Inactive
Thrombins are formed from another inactive substance present in the ___ called _______.
Plasma
Prothrombin
An enzyme complex ____is req for the confusion of prothrombin into thrombin .
Thrombokinase
_______is formed by a series of linked enzymic reactions (cascade process) involving a number of factors present in the plasma in an inactive state .
Enzyme thrombokinase
An injury or trauma stimulates the ___ in the ____ to release ____which activate the mechanism of COAGULATION .
Platelets
Blood 🩸
Certain factors
Certain __released AT _______ also can initiate coagulation .
Factors
The site of injury
____play a very imp role in clotting .
Ca2+
As the blood passes through the he capillaries in tissues , some ___along with many _____ move out into the spaces between the cells of ___.
Water
Small water soluble substances
Tissues
When water along with many water soluble substances move out into the spaces btw the cells of tissues , they leave -______in the _____.
Larger proteins and most of the formed elements
Blood vessels
The fluid released out from capillaries is called -
Interstitial fluid /tissue fluid
Tissue fluid /interstitial fluid has the same MINERAL DISTRIBUTION as in ______.
Plasma
Exchange of nutrients ,gases etc., between blood and the cells always occurs through the_____.
Interstitial fluid /tissue fluid
An elaborate network of ____called the _____collects the tissue fluid /interstitial fluid and drains it back to the ____.
Vessels
Lymphatic system
Major veins
Lymph is a colourless fluid containing _____.
Specialised lymphocytes
Function of interstitial fluid /tissue fluid -
Exchange of nutrients / gases etc btw the blood and the cells always occurs through this fluid .
The fluid present in the lymphatic system is called -
Lymph
Lymph contains specialised lymphocytes which are responsible for -
Immune responses of the body
Lymph is also an important carrier for _____,__etc .
Nutrients
Hormones
Fats are absorbed through ___in the ___present in the ______.
Lymph
Lacteals
Intestinal villi
The circulatory patterns are of 2 types -___and __.
Open
Closed