Blood Vessels and Circulation - Exam 1 Flashcards

1
Q

What happens to blood pressure as you move away from the heart?

A

Systemic blood pressure decreases

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2
Q

If the artery is farther away from the heart, what happens to it’s connective tissue and therefore pressure?

A

There is less connective tissue, therefore less pressure

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3
Q

What are arteries more composed of compared to capillaries and veins?

A

smooth muscle

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4
Q

What does the adventitia in arteries have and do?

A

cross sections of blood vessels to allow oxygen, nutrients, and blood from the outside in and vice versa

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5
Q

What are fenestrated capillaries?

A

capillaries that have holes, allowing for exchange of larger material such as proteins

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6
Q

What are sinusoid capillaries?

A

capillaries that have even bigger gaps for even larger exchange

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7
Q

Where are sinusoid capillaries found?

A

liver and bone marrow

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8
Q

What are the two types of pressures controlling fluid movement across capillary walls?

A

hydrostatic and colloid osmotic

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9
Q

What is hydrostatic pressure?

A

fluid pressure
fluid pressing on walls
higher fluid inside vs interstitial, fluid will push out

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10
Q

What is colloid osmotic pressure?

A

driven by solutes
colloid= something in suspension
high solutes and low water causes water to flow in

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11
Q

What happens if there is a high amount of sodium in the blood?

A

will go down concentration gradient to surrounding tissues

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12
Q

What is a good indicator of what is going on around it?

A

blood

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13
Q

What kind of exchange does interstitial fluid allow?

A

free exchange between plasma and fluid

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14
Q

What kind of exchange does intercellular fluid allow?

A

no free exchange

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15
Q

What organ requires highly regulated exchange with capillaries?

A

Brain

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16
Q

How do blood vessels in the brain behave?

A

endothelial cells that line vessels have tight junctions that cut off the free route between cells, which forces the fluid through the cell for higher regulation and less pressure buildup

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17
Q

If the walls of veins are thinner than arteries, why don’t they burst?

A

low pressure throughout the veins makes it less likely to burst

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18
Q

How much blood is in your veins and why?

A

65% because veins are a sink for blood

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19
Q

What are the 4 ways that blood returns to the heart under low pressure and which are most important?

A
muscular pump
semilunar pump
sympathetic NS
respiratory pump
most important are the first 3
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20
Q

What happens during muscular pump blood return?

A

most likely skeletal contractions to push blood through arteries and veins

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21
Q

What happens during semilunar valve blood return?

A

contractions cause blood to open semilunars

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22
Q

What happens during sympathetic NS blood return?

A

causes venoconstriction

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23
Q

What are varicose veins a result from?

A

deformed and nonfunctional venous valves

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24
Q

What actually happens during the formation of varicose veins?

A

pressure builds up if semilunars cant be pushed open

blood vessels are stretched due to blood buildup

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25
Where are varicose veins most common?
superficial veins
26
What are varicose veins in the anus called?
hemorrhoids
27
What is an important nutrient needed to keep hemorrhoids less painful?
fiber
28
What is perfusion?
amount of blood flow to tissues
29
What is tissue perfusion influenced by?
vascular tone in supplying arterioles | relaxing the blood vessels will lower blood pressure and you will die because tissue perfusion will not occur
30
What are the three types of autoregulation?
metabolic controls myogenic controls long-term autoregulation
31
What is metabolic autoregulation?
byproducts of metabolism (CO2) | causes vasodilation and increased perfusion
32
What is myogenic autoregulation?
arterioles constrict to limit the amount of blood going to capillaries which decreases capillary BP
33
What is long-term autoregulation?
angiogenesis (formation of more blood vessels) for increased blood flow
34
What preludes capillaries to constrict and shunt blood?
Precapillary sphincters
35
What is blood pressure the result of?
flow is opposed by resistance
36
What causes resistance in arteries?
vasoconstriction
37
What are the three factors that maintain BP?
cardiac output peripheral resistance blood volume
38
What happens when you increase the influence of the parasympathetic nervous system?
increased heart rate
39
What are the short-term controls of blood pressure?
neural controls hormonal controls shear stress
40
What is the fastest short-term control system to regulate BP?
Neural controls
41
What are the two types of neural controls?
``` vasomotor center (brain stem) baroreceptors and chemoreceptors ```
42
What happens to baroreceptors when BP is too high?
blood pushes against them to tell brain that it is too high
43
What does stroke volume and the sympathetic nervous system do when BP is too high?
decreases stroke volume sympathetic NS drops heart rate cardiac output is decreased
44
What does vasodilation do to peripheral resistance?
decreases it
45
What happens to baroreceptors that would cause one to remain in a hypertensive state?
they reset with firing at a continuous rate
46
Where are chemoreceptors located?
aortic arch and large arteries of the neck
47
What do chemoreceptors detect?
pH, CO2, blood ox. levels
48
How do chemoreceptors respond to low O2, high CO2, or low pH?
signal generated to increase gas exchange by increasing cardiac output and vasoconstriction
49
What types of hormones increase blood volume?
epinephrine, aldosterone, ADH
50
What types of hormones decrease blood volume?
ANP, Angiotensin, Angiotensin II
51
What does shear stress do to blood pressure?
stimulates release of nitric oxide causing vasodilation
52
How do the kidneys contribute to long-term control of BP?
direct and indirect mechanisms direct= change fluid filtration rate indirect= renin-angiotensin-aldoesterone system
53
What are the 3 types of circulatory shock?
hypovolemic shock vascular cardiogenic
54
What is the BP values of hypertension?
140/90
55
What is essential/primary hypertension?
no known cause (95% of cases)
56
What is secondary hypertension?
known cause
57
What causes hypertension?
anything that increases SV, HR, BP | change in peripheral resistance, effect of ADH, aldosterone etc
58
What is the BP reading for prehypertension?
135/85
59
How does atherosclerosis start?
endothelial dysfunction (hyperlipidemia) turbulent blood flow which decreases sheer stress
60
What does atherosclerosis stimulate?
the release of LDL (bad cholesterol)
61
What engulfs LDL in atherosclerosis and what happens because of it?
macrophages digest it and become foam cells | macrophages eventually burst, causing the release of one fat cell
62
What are the consequences of a blocked artery in the heart?
coronary artery disease | can result in heart attack
63
What are the consequences of a blocked artery in the peripheral blood vessels?
peripheral artery disease | can result in gangrene and amputation
64
What are the consequences of a blocked artery in the brain?
stroke
65
What are the methods of treating blockages in coronary arteries?
coronary bypass surgery | angioplasty or stent implantation
66
What is a problem associated with angioplasty and stent formation?
restenosis (re-closure of vessels)
67
What are aneurysms?
localized dilatation of a part of the cardiovascular system
68
What causes aneurysms?
infection of arteriole wall high BP artherosclerosis
69
What are the treatment options for aneurysms?
repair blood vessels via clipping or coiling