Blood supply & drainage Flashcards
Which structures form the blood-brain barrier?
What is its function?
- endothelium of capillaries w/ tight junctions
- underlying basal membranes
- processes of astrocytes
⇒ protection of neurotoxic substances/potential neurotransmitters from the blood
What are neurohemal organs?
Examples.
circumventricular organs w/ interrupted blood-brain barrier due to
- secretory (pituitary) function
- sensory (area postrema) function
Describe the pathway of the 4 parts of a. carotis interna.
- pars cervicalis → base of the skull (acc. by n. vagus, v. jugularis int.)
- pars petrosa (C5) through canalis caroticus
- pars cavernosa (C4 - C3) in sinus cavernosus, forms S-shaped siphon caroticum
- pars cerebralis (C2 - C1) pierces dura mater, gives off 4 final cerebral branches in cisterna carotica
Why is pars cavernosa of a. carotis int. clinically important?
can exert pressure on all nn. located in/around sinus cavernosus
→ possible damage in case of aneurysm
What are the branches of a. carotis int.?
pars cervicalis: -
pars petrosa: aa. caroticotympanicae
pars cavernosa:
- a. hypophysialis inf. → pituitary
- a. meningea centralis → tentorium cerebelli
- rr. gangilionares trigeminales, rr. marginalis tentorii
pars cerebralis:
- a. ophtalmica through canalis opticus → eye, paranasal sinuses, anastomosis w/ a. facialis
- a. hypophysialis sup. → pituitary
- aa. encephali
- r. meningeus
What are the branches of aa. encephali (=a. carotis int.)?
- a. communicans post. forms anastomosis in circle of Willis
- a. choroidea ant.
- a. cerebri ant. part of circle of Willis
- a. cerebri med. part of circle of Willis
cf. circle of Willis drawings
A. carotis is after the aa. coronaria the artery second most affected by atherosclerosis.
What are possible consequences?
- contralateral paralysis due to insufficient supply of motor and premotor cortex
- sensitive disorders due to insufficient supply of sensitive cortex
- speech disorders
- visual disorders due to insufficient supply of retina by a. ophthalmica
Where are all aa. of arterial circle of Willis located?
Clinical relation?
spatium subarachnoideum
→ in case of aneurysms blood can be detected in the liquor
⇒ heavy pain due to meningeal irritation + spasms of brain supplying aa., always life-threatening
´
1a - e
1a) a. carotis int. - pars petrosa (C5)
1b) a. carotis int. - pars cavernosa (C4)
1c) a. carotis int. - siphon caroticum (C3)
1d) a. carotis int. - pars cerebralis, cisterna carotica (C2)
1e) a. carotis int. - pars cerebralis (C1)
2 - 6
2) chiasma opticum
3) a. ophthalmica
4) a. cerebri ant.
5) a. communicans a.
6) a. cerebri med.
7 - 11
For clarification: #9 is a branch of #1e
7) a. choroidea ant.
8) a. communicans post.
9) a. hypophysialis sup.
10) a. hypophysialis inf.
11) a. cerebri post.
12 - 16
12) a. sup. cerebelli
13) a. basilaris
14) a. inf. ant. cerebelli
15) a. labyrinthi
16) aa. pontis
17 - 21
17) a. inf. post. cerebelli
18) a. vertebralis
19) a. spinalis ant.
20) n. ophthalmicus
21) n. maxillaris
22 - 25
22) n. mandibularis
23) n. oculomotorius
24) rr. ganglionares for ganglion of n. trigeminus
25) rr. tentorii
Which aa. supply the cerebellum?
Which further structure is supplied by them?
- a. basilaris → a. sup. cerebelli
- a. basilaris → a. inf. ant. cerebelli
- a. vertebralis → a. inf. post. cerebelli
additionally plexus choroideus of 4th ventricle
Which areas are partially supplied by a. communicans post.?
It forms an anastomosis btw which aa.?
supplies
- visual pathway
- sub-/hypothalamus (tuber cinereum, corpora mammilaria, pars post. hypothalami), thalamus
forms anastomosis btw a. carotis int. pars cerebralis + a. cerebri post.
Which areas are partially supplied by a. choroidea ant.?
It forms an anastomosis w/ … ?
supplies
- telencephalon (hippocampus, amygdala, ncl. caudatus, pallidum, crus post. of capsula int.)
- thalamus
- midbrain (crura cerebri, substantia nigra, ncl. ruber)
- visual pathway (chiasma opticum, tr. opticus, corpus geniculatum lat.)
- forms rr. of plexus choroideus in lat. ventricles
forms anastomosis w/ rr. choroidei post. from a. cerebri post.
What are the 2 segments of a. cerebri ant.?
Which areas are supplied by it?
2 parts: A1 → a. communicans ant., A2 after
- pars precommunicalis (A1)
- pars postcommunicalis (A2)
⇒ supplies basal part of frontal lobe, medial part of frontal and parietal lobe → sulcus parietoocc.
= sensory/motor centers of lower limbs