Blood pressure disorders Flashcards

1
Q

what defines hypertension

A

> 140/90 // 24hr >135/85 (ABPM - recommended)

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2
Q

what symptoms may appear with sevre hypertension >180 systolic or >120 diastolic

A

headaches, visual disturbance, seizures –> refer to specialist

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3
Q

what other tests are done following HTN diagnosis

A

U+E, HbA1c, lipids, urine, ECG, fundoscopy

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3
Q

what other tests are done following HTN diagnosis

A

U+E, HbA1c, lipids, urine, ECG, fundoscopy

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4
Q

when is ABPM or HBPM offered

A

following a BP of 140/90 (should measure both arms)

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5
Q

how is ABPM monitered

A

2 measurements per hour in a waking day

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6
Q

what is stage 1 hypertension

A

clinical BP >140/90 + HBPM >135/85

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7
Q

what is stage 2 hypertension

A

clinical BP >160/100 + HBPM >150/95

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8
Q

what is severe hypertension

A

clinical systolic > 180 or diastolic >120

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9
Q

how is HBPM done

A

take 3 readings in one sitting // twice daily // for 4 - 7 days // discard first day and average out the others

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10
Q

when should treatment be considered in HTN

A

if stage 1: 80+ + end organ damage or CVD 10 yr risk >10% // all stage 2 + 3

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11
Q

lifestyle advice mx for HTN

A

low salt (<6g a day) // low caffeine // stop smoking

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12
Q

1st line mx HTN in patient <55 or T2DM

A

ACEi (or ARB if cough)

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13
Q

2nd line mx HTN in patient <55 or T2DM

A

add a CCB or (thiazide diuretic) eg A + C or A + D

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14
Q

1st line mx HTN patients 55+ or black

A

CCB

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15
Q

2nd line mx HTN patients 55+ or black

A

add on an ACEi/ARB OR a diuretic eg C + A or C + D

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16
Q

3rd line HTN mx in all patients

A

triple therapy eg A + C +D

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17
Q

4th line mx for all HTN patients

A

K <4.5 = spironolactone // K > 4.5 = alpha or beta blocker

18
Q

BP aim in patients 80+

A

150/90 or ABMP 145/85

19
Q

BP aim in T2DM

20
Q

BP aim in T1DM

A

135/85 (or albuminuria 130-80)

21
Q

what drug is 1st line for HTN in diabetic patients regardless of age

A

ACEi or (ARBs in black diabetic patients)

22
Q

who commonly gets orthostatic hypotension

A

older people, parkinsons, diabetes!, hypertension

23
Q

what drug can commonly cause orthostatic hypotension

A

alpha blockers

24
invx orthostatic/ postural hypotension
drop in BP >20s (or >10d) within 3 minutes of standing
25
mx orthostatic hypotension
increase salt + fluid // midodrine and fludrocortisone
26
what is syncope
transient LOC from cerebral hypoperfusion --> rapid onset --> short duration --> complete recovery
27
3 categories of syncope
reflex: vasovagal, situational, carotid sinus // orthrostatic: parkinsons, drugs, low BP // cardiac: arrhythmia, structural, PE
28
inheritance familial hypercholesterolaemia
autosomal dominant
29
mutation in familial hypercholesterolaemia
gene for LDL receptor protein --> high levels of LDL
30
when should familial hypercholesterolaemia be considered
cholesterol >7.5 OR FH of premature CVD (under 60)
31
when should children of familial hypercholesterolaemia be testes
1 parent = age 10 // 2 parents = age 5
32
which criteria diagnoses familial hypercholesterolaemia
simon broome criteria
33
mx familial hypercholesterolaemia
1st line = high dose statin
34
aside from high cholesterol what additional criteria needs to be met for diagnosis of familial hypercholesterolaemia
tendon xanthoma in 1st/ 2nd degree relative or FH of genetics
35
what is xanthoma + xanthelasma
yellow plaques from cholesterol/ lipid deposits // xanthelasma on the eyes
36
mx xanthelasma
surgery // topical trichloroacetic acid // laser therapy // electro removal
37
what criteria is used to determine someones 10 year risk of CVD
QRISK2
38
how is hyperlipidaemia diagnosed
cholesterol + HDL (>7.5)
39
1st line mx of primary prevention hyperlipidaemia
20mg atorvastatin
40
what disease may a statin be considered in all adult patients
T1DM + CKD
41
statin dose for secondary prevention of CVD
80mg atorvastatin (max dose)
42
what additional treatment can be offered in hyperlipidaemia + SE
nicotonic acid --> flushing + impaired glucose tolerance
43
when is ezetimibe indicated
primary heterozygous hypercholesterolaemia (mono therapy or + statin)