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Physiology > Blood numbers (mostly) > Flashcards

Blood numbers (mostly) Flashcards

1
Q

components of blood

A

plasma,rbc,wbc,platelets

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2
Q

plasmas percentage of bodyweight/ plasmas total blood volume percentage

A

4%/54%

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3
Q

red blood cells percentage of total blood volume/concentration

A

44-45% of total blood volume/3.6x10^6/ul-5.5x10^6/ul

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4
Q

wbc concentration

A

5-10x10^3/ul or 5000-10000/ul

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5
Q

platelet concentration

A

150,000-350000/ul

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6
Q

platelets/wbc (buffy coat) percentage of total blood volume

A

.5-1%

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7
Q

plasma components

A

90% water 10% solute (proteins,electrolytes,organic compounds)

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8
Q

Amount of proteins in plasma

A

6.8-8 gm/dl

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9
Q

Amount electrolytes in plasma

A

900 mg/dl

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10
Q

albumin in plasma/ percentage of total plasma protein

A

4.5 gm/dl, 62%

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11
Q

globulins in plasma and percentage of total protein in plasma

A

2.5 gm/dl, 34.2%

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12
Q

fibrinogen in plasma and percentage of total protein in plasma

A

300 mg/ dl, 4%

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13
Q

MW of albumin

A

66,000 g/mol

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14
Q

amount of albumin produced by liver everyday

A

14-17 grams approx 9% of total albumin

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15
Q

alpha 1 globulin percentage of total plasma protein

A

4%

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16
Q

alpha 2 globulin percentage of total plasma protein

A

8%

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17
Q

beta globulin percentage of total plasma protein

A

12%

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18
Q

gamma immunoglobulin percentage of total plasma protein

A

16% 1.5 gm/dl

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19
Q

globulin functional groups

A

plasma proteolytic proteins, plasma protease inhibitors, carrier proteins, acute phase proteins

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20
Q

types proteolytic protein systems

A

complement, kinin,blood coag,fibrinolytic

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21
Q

plasma protein inhibitors

A

a-macroglobulin, antithrombin 3, c1 inhibitor, a2 plasmin inhibitor

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22
Q

acute phase proteins

A

hemostatic factors (fibrinogen, van Willenbrand factor),C3 and B components of complement, Haptoglobin, protease inhibitors alpha 1 antichymotripsin, alpha 2 antiplasmin, C reactive protein

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23
Q

dimensions of RBC SHAPE, DIAMETER greatest thickness, least thickness, area volume

A

biconcave discoid, diameter:8.1 microns, greatest thickness: 2.7 microns, least thickness 1.0 micron, area 138 microns^2, volume 95 microns ^3

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24
Q

RBC contents by volume percentage

A

water= 70%, 25% hemoglobin, 5% other

25
Q

ionic concentrations in blood for: sodium, potassium, chloride, bicarbonate, protein

A

18 mEq/l, 81 mEq/l, 52 mEq/l, 19 mEq/l, 5 mMol/L

26
Q

of molecules in RBC

A

300 million

27
Q

total O2 CONTENT DISSOLVED IN PLASMA

A

2%

28
Q

henrys law

A

(O2 dis)=(PO2)(.003 ml O2/dl/mmHg)

29
Q

percentage of O2 bound to Hb

A

98%

30
Q

importance of Ca, K, Na

A

normal impulse conduction in nerves and muscle fibers

31
Q

importance of Ca

A

coagulation and cardiac muscle contraction

32
Q

importance of K

A

maintains cardiac rhythm

33
Q

Importance of cl

A

replaces bicarbonate ions taken-up by RBCs

chloride shift

34
Q

importance of Na Cl

A

maintains fluid balance between blood & body tissues

35
Q

importance of Mg

A

promotes normal neuromuscular function

36
Q

importance of bicarbonate

A

not electrolyte –maintains normal acid- base status – major body buffer

37
Q

homozygous S production of Hb vs heterozygous

A

100% Hb S, vs. 40 % Hb S and 60% Hb A

38
Q

percentages of wbc count

A

neutrophils 60-70%, eosinophils 2-4 %, basophils .5-1%, monocytes 3-8 % , lymphocytes 20-25%

39
Q

neutrophil sensitivity to chemotactic molecules

A

1 billionth of a mole or 1 nM

40
Q

neutrophilic structure and concentration

A

10-15 microns in diameter, polymorhonuclear (2-5 lobes ont the nucleus), approx 5,500/ul

41
Q

eosinophils diameter and concentration

A

12-17 microns in diameter, approx 10-760/ul

42
Q

basophils diameter and concentration

A

5-7 microns in diameter 10-250/ul

43
Q

monocyte diameter and concentration

A

12-20 microns, 20-1000/ul

44
Q

lymphocyte concentration and diameter

A

650-4500/ul (with T cells being 75% of that), 5-12 microns

45
Q

platelet diameter and concentration

A

2-4 microns 250,00/ul

46
Q

daily production erythrocytes

A

3 x 10^9/kg of body weight

47
Q

daily production granulocytes

A

1.6 x 10^9

48
Q

daily production monocytes

A

1.7x 10^8a

49
Q

daily production eosinophils basophils and lymphocytes

A

variable, unknown

50
Q

daily production platelets

A

2.8 x10^9

51
Q

Type A percentage of pop.

A

41%

52
Q

percentage of pop. Type B

A

9%

53
Q

percentage of pop. Type AB

A

3%

54
Q

percentage of pop. Type O

A

47%

55
Q

percentage of pop. D+/Rh+

A

85%

56
Q

whole blood/ packed cells temp. and shelf life

A

1-6 degrees celsius, refrigerated shelf life of 21 days( CPD/CP2D), 35 days CPDA-1)

57
Q

pack cells shelf life

A

42 days

58
Q

platelets shelf life and temp

A

20-24 degrees C SHELF LIFE OF 5 days while being slowly rocked

59
Q

plasma shelf life and temp

A

frozen at -18 degrees celsius, shelf life of 1 year

Physiology (27 decks)

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