Blood & Lymphatic System (Chapter 11) Flashcards
presence of RBCs of unequal size
anisocytosis
presence of bacteria in the bloodstream
bacteremia
abnormally reduced number of RBCs
erythropenia
rupture of RBC membrane
hemolysis
loss of blood from circulation
hemorrhage
abnormally large RBCs
macrocytosis
large, irregularly shaped RBCs
poikilocytosis
abnormal increase in the number of erythrocytes in the blood
polycythemia
abnormal enlargement of the spleen
splenomegaly
presence of toxins in the blood
toxemia
acquired immune deficiency syndrome: caused by HIV, which disables immune response by destroying mainly helper T cells (which activate B cells); loss of immune function allows opportunistic infections to proliferate & eventually cause death
AIDS
response to an allergen, which is an antigen that produces a hypersensitivity reaction that includes immediate inflammation but does not elicit other immune responses; allergies are of many types, most common are allergic rhinitis (hay fever) which affects the mucous membranes of the nasal cavity & throat, & allergic dermatitis which affects the skin where it has made contact w/ the allergen
allergy
immediate reaction to an antigen that includes rapid inflammation & systemwide smooth muscle contractions
anaphylaxis
reduced ability of RBCs to deliver oxygen to tissues, resulting from a reduction of circulating RBCs, amount of hemoglobin, or the volume of RBCs; common forms include aplastic, iron deficiency, sickle cell, & pernicious
anemia
anemia characterized by the failure of red bone marrow to produce enough RBCs
aplastic anemia
any of several diseases that is caused by a person’s own immune response attacking otherwise healthy tissues; includes rheumatoid arthritis, systemic lupus erythematosus, & multiple sclerosis
autoimmune disorder
form of poisoning caused by the ingestion of food contaminated w/ the toxin produced by the bacterium clostridium botulinum
botulism
disease caused by a bacterium & its toxin, resulting in inflammation of mucous membranes, primarily in the mouth & throat
diphtheria
general term for an abnormal condition of the blood
dyscrasia
blood disorder that results from incompatibility between a fetus w/ Rh positive blood & its mother w/ Rh negative blood; causes the destruction of fetal RBCs & requires blood transfusions to save the fetus; Rh mismatch, hemolytic disease of newborn
erythroblastosis
fungal infection distributed by way of the bloodstream
fungemia
infection of a wound caused by various anaerobic bacteria; produces a fermentation gas, necrosis, & septicemia
gas gangrene
inherited disorder that results in an excessive accumulation of iron deposits in the body
hemochromatosis
inherited bleeding disorder that results from defective clotting proteins involved in blood coagulation
hemophilia
cancer of lymphatic tissue; characterized by the progressive enlargement of lymph nodes, fatigue, & deficiency of the immune response
Hodgkin’s disease
condition that results from a defective immune response
immunodeficiency
reduction of an immune response caused by disease or, in the case of organ transplants, by the use of chemical, pharmacologic, physical, or immunologic agents
immunosuppression
multiplication of disease causing microorganisms w/in the body
infection
swelling of body tissue caused by movement of plasma into the extracellular space to produce edema (fluid accumulation) in tissue; protective response of body tissues to irritation or injury; symptoms include swelling, redness, heat, & pain
inflammation
viral disease characterized by a temporary inflammation of mucous membranes & fever; commonly called the flu, virus is highly contagious & capable of mutation to escape detection by WBCs
influenza
anemia that is caused by a lack of iron, resulting in smaller RBCs containing deficient levels of hemoglobin
iron deficiency anemia
cancer of the red bone marrow, which is the blood forming tissue; characterized by an increased number of WBCs, many of which are abnormal & nonfunctional
leukemia
inflammation of the lymph nodes
lymphadenitis
literally, disease of the lymph nodes; this general term is often applied to a syndrome (LAS: lymphadenopathy syndrome), which is a persistent swelling of the lymph nodes that often precedes the onset of AIDS
lymphadenopathy
tumor that originates in lymphatic tissue
lymphoma
disease caused by a parasitic protozoan that infects RBCs & is carried by Anopheles mosquitoes; characterized by periodic fevers & fatigue
malaria
viral disease characterized by enlarged lymph nodes, atypical lymphocytes, sore throat (pharyngitis), fever, & fatigue
mononucleosis
bone marrow disorder characterized by the proliferation of abnormal stem cells; usually develops into a form of leukemia
myelodysplasia
disorder that usually consists of bacterial infections contracted during a hospital stay (often MRSA)
nosocomial infection
anemia caused by insufficiency of vitamin B12, resulting in RBCs that are large, varied in shape, & reduced in number
pernicious anemia
any infectious disease of wide prevalence or excessive mortality; can also refer to an acute infectious disease caused by Yersinia pestis characterized by high fever, skin eruptions, internal hemorrhage, & pneumonia (bubonic plague)
plague
viral infection spread from the mouth of an infected animal, usually by biting; virus produces a neurotoxin that acts on the CNS & is highly fatal
rabies
systemic disease caused by the presence of bacteria & their toxins in the circulating blood; person suffering from this is referred to as “septic”
septicemia
inherited, chronic anemia characterized by defective hemoglobin that causes RBCs to become misshapen, resulting in drowsiness, leg ulcerations, fever, joint & abdominal pain, & thrombosis
sickle cell anemia
staph infection: presence of Staphylococci bacteria in the blood; frequent complication to normal healing & is the most common cause of food poisoning, skin inflammation, osteomyelitis, & nosocomial infections
staphylococcemia
disease caused by a powerful neurotoxin released by the common bacterium Clostridium tetani; toxin acts on the CNS to cause convulsions & paralysis
tetanus
tumor that originates in the thymus gland
thymoma
therapeutic treatment in which a substance w/ known toxicity to bacteria is administered; obtained from fungus or other bacteria; effective only against bacteria, many types of which are capable of developing resistance, especially when not administered properly
antibiotics
chemical agent that reduces the clotting process
anticoagulant
application of drugs to battle against a class of viruses that tend to mutate quickly, known as retroviruses (ex. HIV); also known as combination therapy because the drugs form a cocktail of nucleotide analog reverse transcriptase inhibitors & protease inhibitors, blocking HIV replication
antiretroviral therapy
process in which pathogens are rendered less virulent, prior to their incorporation into a vaccine preparation
attenuation
transfusion of blood donated by a patient for personal use; common procedure before a surgery to avoid potential incompatibility or contamination
autologous transfusion
field of science & medicine focused on study of bacteria & prevention of bacterial diseases
bacteriology
test or series of tests on blood samples to measure the levels of particular components
blood chemistry
test to determine infection in the blood by placing a blood sample on a nutritive media in an effort to grow populations of bacteria for analysis
blood culture
introduction of blood, blood products, or a blood substitute into a patient’s circulation to restore blood volume to normal levels
blood transfusion
timed blood test to determine time required for a blood clot to form; prothrombin time (PT) measures time required for prothrombin (precursor protein) to form thrombin & is used to monitor anticlotting therapy, & partial thromboplastin time (PTT) which evaluates clotting ability
coagulation time
common laboratory blood test to provide diagnostic information of a patient’s general health; includes hematocrit, hemoglobin, red blood count, & white blood count
complete blood count (CBC)
microscopic count of the number of each type of WBC, using a stained blood smear
differential count
timed test to measure the rate at which RBCs fall through a volume of plasma to provide information on their hemoglobin content; commonly used to evaluate nonspecific systemic inflammation
erythrocyte sedimentation rate (ESR)
test that measures the percentage of RBCs in a volume of blood; obtained from centrifuging a sample of blood to separate blood cells
hematocrit (HCT/Hct)
general field of medicine that focuses on blood related disease
hematology
test that measures the level of hemoglobin in RBCs
hemoglobin (HGB/Hgb)
stoppage of bleeding
hemostasis
transfusion of blood that is voluntarily donated by another person; requires blood type matching, known as crossmatching, to prevent incompatibility
homologous transfusion
procedure that provides immunity against a particular antigen
immunization
study concerned w/ immunity & allergy
immunology
treatment of infectious disease; use of agents to activate or strengthen the immune response
immunotherapy
removal of lymph nodes for pathological study to assist in a diagnosis - biopsy
lymph node dissection
excision of a lymph node
lymphadenectomy
process of x-ray photography of the lymph nodes following injection of a contrast medium
lymphadenography
incision into a lymph node
lymphadenotomy
process of x-ray photography of lymphatic vessels following injection of a contrast medium
lymphangiography
removal of a donor’s blood, which is then separated into blood components, w/ one portion retained for use & the remainder returned to the donor; includes plasmapheresis (plasma), leukapheresis (WBCs), & plateletpheresis (platelets)
pheresis
calculation of the number of platelets in the blood
platelet count (PLT)
any treatment that tends to prevent the onset of an infection or other type of disease
prophylaxis
measures the number of RBCs per cubic centimeter (cc)
red blood count (RBC)
excision of the spleen
splenectomy
surgical fixation of the spleen
splenopexy
process of dissolving a blood clot
thrombolysis
excision of the thymus gland
thymectomy
field of medicine that focuses on the study of toxins & the diseases they cause
toxicology
inoculation of a culture that has reduced virulence, as a means of providing a cure or prophylaxis
vaccination
any preparation used to activate an immune response
vaccine
field of medicine that focuses on the study of viruses & the treatment of the diseases they cause
virology
measures the number of WBCs per cubic centimeter
white blood count