blood infections Flashcards

1
Q

blood infection disease

A

bacterial : sepsis&septic shock. rheumatic fever, anthrax, brucellosis,plague,leptospirosis,lyme disease, Q fever.

viral: Burkitt’s lymphoma, mononucleosis, CMV AIDS heaemorrhagic fever
fungi: candidiasis

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2
Q

sepsis and septic shock stage:

A
  1. infalmmation and release of cytokines

2. lymphangitis, inflamed lymph vessels

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3
Q

sepsis G- pathogen

A

E.coli/ Klebsiella/ Pseudomonas

endotoxin

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4
Q

sepsis G+ pathogen

A

S. aureus. S. pyogenes
potent exotoxins(superantigens). TSST(toxic shock syndrome toxin)
Enterococci(hosptial aquire)

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5
Q

puerperal sepsis pathogen

A

group A strep: streptococcus pyogenes(b-haemolytic)

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6
Q

puerperal sepsis known as

A

childbirth or childbed fever

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7
Q

puerperal sepsis infect ___

A

uterus

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8
Q

anthrax pathogen

A

bacillus anthracis:

  • large aerobic G+ rods . endospore-forming
  • affect cattle and sheep
  • disease rare in human
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9
Q

three form of anthrax

A
  1. cutaneous anthrax—–cantact spore
  2. gastrointestinal anthrax—–rare. ingest spore
  3. inhalation( pulmonary anthrax)
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10
Q

anthrax pathogenicity

A
  1. exotoxin enzymes:a.Edema factor(EF) b.Lethal factor(LF)

2. PA (protective antigen) binds the toxin to target cells.

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11
Q

brucellosis pathogen

A

brucella spp

-G- coccobacilli

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12
Q

subacute bacterial endocarditis pathogen

A

most a-haemolytic streptococci

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13
Q

subacute bacterial endocarditis transmission

A

dental work

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14
Q

acute bacteral endocarditis pathogen

A

staphylococcus aureus

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15
Q

rheumatic fever pathogen

A

strep. pyogenes(Group A)

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16
Q

burkitt’s lymphoma pathogen

A

EBV(hhv 4)

17
Q

most common childhood cancer in africa

A

burkitt’s lymphoma

18
Q

EBV(hhv 4) cause

A
  1. mononucleosis(self-limiting)

2. burkitt’s lymphoma(fatal)

19
Q

CMV pathogen

A

HHV 5

20
Q

HHV5 remain in

A

monocytes, neutrophils and T cells

21
Q

HHV4 remain in

A

B cells

22
Q

CMV shed virus in

A

saliva, semen, breast milk

23
Q

CMV microscope shape

A

owl’s eyes

24
Q

CMV symptoms

A
  1. healty: asymptoms
  2. immunocompromised: life- threatenting
  3. AIDs- cmv retinitis
  4. pregnancy—-fatal ,abrostion
25
Q

CMV transmission

A

kiss, sexually, transfused, tranplantation

26
Q

viral haemorrhagic fever

A
  1. yellow fever
  2. dengue haemorrhagic fever
  3. Ebola
  4. AIDS