Blood Glucose Levels and Obesity Unit 2 Flashcards

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1
Q

How much sugar should be in the blood plasma usually ?

A

Around 5 millimoles per litre (5mmol/l)

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2
Q

How much sugar can be found in the blood of a diabetic person ?

A

Sometimes as much as 30mmol/l

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3
Q

Which part of the blood vessels absorbs the excess glucose if a diabetic person ?

A

The endothelium of the blood vessels

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4
Q

What happens to blood vessels that take in more glucose than usual ?

A

They become weaker and burst and bleed into surrounding tissues

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5
Q

What name is given to the condition caused by blood vessels that burst due to the weight of glucose in them ?

A

Microvascular disease

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6
Q

What organs can microvascular disease affect ?

A

Retina of the eyes, kidneys and the body’s extremities like the arms and legs

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7
Q

What is glucose stored as in the liver ?

A

Glycogen

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8
Q

Whenever glucose concentration rises following a meal, receptor cells in which organ detects it ?

A

Pancreas

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9
Q

Which hormone is released by the pancreas following a rise in blood glucose levels ?

A

Insulin

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10
Q

What organ does insulin hormone released by the pancreas go to ?

A

The Liver

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11
Q

What reaction is triggered in the liver by the hormone insulin ?

A

Glucose —> Glycogen

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12
Q

When glucose is converted to glycogen in the liver, what does this do to blood glucose levels ?

A

Lowers it

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13
Q

Whenever glucose levels fall and are ‘fone’ from the blood following a period without food or after sleeping, which organ detects it ?

A

The pancreas

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14
Q

Which hormone is released by the pancreas following a fall in blood glucose levels ?

A

Glucagon

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15
Q

What organ does glucagon hormone released by the liver go to ?

A

The liver

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16
Q

What reaction is triggered in the liver by the hormone glucagon ?

A

Glycogen —> Glucose

17
Q

When glycogen is converted to glucose in the liver and the glucose is release into the blood, what does this do to blood glucose levels ?

A

Raise it

18
Q

The constant retiring of glucose levels to a set point operates on what principle ?

A

Negative feedback control

19
Q

Which hormone can promote the conversion of more glycogen to glucose in the liver to increase the supplies of glucose in the blood ?

A

Adrenaline

20
Q

When would adrenaline be released ?

A

During exercise or the ‘fight or flight’ reactions

21
Q

Name the two types of diabetes

A

Type 1 and type 2

22
Q

Which type of diabetes is not linked to obesity ?

A

Type 1

23
Q

What type of diabetes is linked to obesity ?

A

Type 2

24
Q

How is type 1 diabetes controlled ?

A

By insulin injection and careful diet

25
Q

In which type of diabetes are the receptors for insulin decreased and least sensitive to insulin ?

A

Type 2

26
Q

Which type of diabetes tends to occur in childhood ?

A

Type 1

27
Q

What would be found in the urine of a diabetic person ?

A

Glucose

28
Q

What test do doctors carry out to diagnose diabetes ?

A

Glucose tolerance test

29
Q

Give a brief description of the glucose tolerance test

A
  • Person fasts for 8 hours
  • Blood glucose levels measure
  • Person given a drink loaded with a known amount of glucose
  • The blood glucose levels are then monitored to see if they come back down to normal within 2.5 hours.
  • The results are plotted to give a glucose tolerance curve
30
Q

What condition is characterised by the accumulation of excess fat compared to lean tissue such as muscle ?

A

Obesity

31
Q

Give three health problems caused by obesity ?

A
  • Osteoarthritis
  • Cardiovascular disease
  • Type 2 diabetes
32
Q

What is the formula for calculating Body Mass Index ?

A

(BMI) = Weight (kg) divided by height in metres squared

33
Q

Who might a BMI not be accurate for ?

A

Bodybuilders as muscle weights more than fat and so the BMI might come out higher than it should be