Blood disorders drugs

Question 1

Types of drugs for blood disorders

Answer 1

Anticoagulants
Thrombolytics (dissolves clots)
Anemia (RBCs lack iron, vitamin B12, or folic acid)

Question 2

Anticoagulants

Answer 2

heparin
warfarin (Coumadin)
dalteparin
enoxaparin

Question 3

heparin

Answer 3

Anticoagulant
Injection only
Monitored by PTT (partial thromboplastin time: intrinsic)
Antidote: protamine sulfate
Safe for pregnancy

Question 4

Generic name: warfarin

Answer 4

Brand name: Coumadin
Anticoagulant
Tablet only
Monitored by PT (prothrombin time: extrinsic)
Interacts with antibiotics and NSAIDs
Not safe for pregnancy

Question 5

Generic name: dalteparin

Answer 5

Brand name: Fragmin

Anticoagulant

Question 6

Generic name: enoxaparin

Answer 6

Brand name: Lovenox

Question 7

thrombolytics

Answer 7

Dissolve clots quickly
Interacts with anticoagulants, anti-platelet drugs, and NSAIDs -> Increased bleeding
streptokinase
urokinase
Anything that ends in -kinase

Question 8

-kinase

Answer 8

dissolves clots quickly

Question 9

anemia

Answer 9

Red blood cells are depleted of iron, vitamin B12, or folic acid

Question 10

iron

Answer 10

travels on hemoglobin in the RBC (hemoglobin carries oxygen)
ex> ferrous sulfate (FeSO4) - Feosol
ferrous gluconate - Fergon
ferrous fismarate - Feostat iron
Concerns:
Must stay away from antacids, coffee, tea, milk
Interferes with TCN (tetracycline)
Take on empty stomach
Stains teeth: Liquid iron for children should be dissolved in juice.

Question 11

Vitamin B-12 deficiency

Answer 11

= Cyanocobalamin deficiency (anemia)
Impaired DNA synthesis
Stunted maturity of RBC

Question 12

Folic acid deficiency

Answer 12

= folate deficiency (anemia)
Impaired DNA synthesis
Stunted maturity of RBC