Anti-neoplastic drugs

Question 1

antineoplastic drugs

Answer 1

cancer chemotherapy drugs, cytotoxic drugs

Question 2

Potential routes of exposure of antineoplastic drugs

Answer 2

Inhalation of aerosolized drug

Skin contact

Question 3

Working with antineoplastic drugs

Answer 3

In Class II laminar flow hood
Work surface is covered with plastic-backed absorbent paper.
Staff gowns with knit cuffs, gloves
Vials should be vented
Label “Caution - Cancer chemotherapy, Dispose of Properly”
Wipe down area with 70% alcohol

Question 4

Disposing of antineoplastic drugs

Answer 4

Needles and syringes should be disposed of intact to prevent aerosol generation, in a leak-proof, puncture-resistant container.
Should be placed in a plastic-lined box, sealed, and incinerated

Question 5

Generic name: bleomycin

Answer 5

Brand name: Blenoxane

Antineoplastic drug

Question 6

Generic name: busulfan

Answer 6

Brand name: Myleran

Antineoplastic drug

Question 7

Generic name: chlorambucil

Answer 7

Brand name: Leukeran

Antineoplastic drug

Question 8

Generic name: cisplatin

Answer 8

Brand name: Platinol

Antineoplastic drug

Question 9

Generic name: cyclophosphamide

Answer 9

Brand name: Cytoxan

Antineoplastic drug

Question 10

Generic name: daunorubicin

Answer 10

Brand name: Cerubidine

Antineoplastic drug

Question 11

Generic name: doxorubicin

Answer 11

Brand name: Adriamycin

Antineoplastic drug

Question 12

Generic name: fluorouracil (5-FU)

Answer 12

Brand name: Efudex

Antineoplastic drug

Question 13

Generic name: hydroxyurea

Answer 13

Brand name: Hydrea

Antineoplastic drug

Question 14

Generic name: lomustine (CCNU)

Answer 14

Brand name: CEENU

Antineoplastic drug

Question 15

Generic name: melphalan

Answer 15

Brand name: Alkeran

Antineoplastic drug

Question 16

Generic name: mercaptopurine

Answer 16

Brand name: Purinethol

Antineoplastic drug

Question 17

Generic name: methotrexate

Answer 17

Brand name: Rheumatrex

Antineoplastic drug

Question 18

Generic name: temozolomide

Answer 18

Brand name: Temodar

Antineoplastic drug

Question 19

Generic name: valrubicin

Answer 19

Brand name: Valstar

Antineoplastic drug

Question 20

Generic name: vinblastine

Answer 20

Brand name: Velban

Antineoplastic drug

Question 21

Generic name: vincristine

Answer 21

Brand name: Oncovin

Antineoplastic drug