Blood Components Flashcards

1
Q

Whole blood is collected in a ratio of _____ of anticoagulant preservative for every _____ of whole blood targeted for collection.

A

14mL, 100 mL

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2
Q

The inability or insufficient production of specific blood components of the body leads to

A

Coagulopathy, and Thrombocytopenia

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3
Q

Three main benefit of component Theraphy

A

Limit the risk of transfusion reaction and overload

Targets the condition or deficiency

Assures the quality of the specimen

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4
Q

This blood components Contains RBC and plasma, with hematocrit level of 38%
- Indication: for increasing both the blood volume and RBC mass
- Collected by venipuncture into blood
specific blood components
insufficient production of
coagulopathy and thrombocytopenia
bags with
preservatives
- Volume: 450-500 mL

A

Whole Blood

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5
Q

This blood components 80% of plasma is removed

Additive solutions: 50 mL of plasma can be removed in exchange for 150 mL of adenine-saline

Volume: 250-300mL

A

Packed RBC

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6
Q

The product most often transfused
during the neonatal period or in infants younger than 4 months of age

  • Very small amount is transfused specially in neonates (10 to 25 mL)
  • Anticoagulant: CPDA01
A

RBC Aliqouts

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7
Q

What is the only FDA approved solution in rejuvenated rbc

A

Rejuvesol

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8
Q

RBC LEUKOREDUCED is prepared by

A

Filtration, Sedimentation and Saline Washing

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9
Q

Also known as random-donor platelets

A

Platelet Concentrate

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10
Q

Can be used to supply transfusions to several neonates or infants

A

Platelet Aliquots

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11
Q

This plasma derivatives indicates hemophilia A, factor VII deficiency

A

Activated Factor VII

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12
Q

This plasma derivatives indicates hemophilia A and classical hemophilia

A

Factor VIII Concentrate

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13
Q

This plasma derivatives, significant levels of vitamin K dependent factors: II, VII, IX, X

A

Factor IX concentrates

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14
Q

This plasma derivatives, Factor XIII deficiency - severe autosomal-recessive bleeding disorder associated with neonatal hemorrage and a lifelong bleeding diathesis

A

FACTOR VIII-CONCENTRATES

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15
Q

This plasma derivatives, Indication: Immunodeficiency diseases, passive antibody prophylaxis

A

Immune serum globulin

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16
Q

This plasma derivatives, Prepared from salvaged plasma

A

Normal serum albumin

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17
Q

This plasma derivatives, Similar to that of NSA, with fewer purification steps
- Contraindication: infusion during cardiopulmonary bypass procedures

A

Plasma protein fraction

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18
Q

This plasma derivatives Indications: Hereditary AT deficiency in connection with surgical or obstetrical procedures or for those
suffering from thromboembolism.

A

Antithrombin III Concentrate

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19
Q

For irradiated blood components use what

A

Cesium 137, and Cobalt 60

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20
Q

Platelet rich plasma can be subjected wit what type of spin (hard/light)

A

Hard Spin

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21
Q

refers to the changes that occur in red blood cells (RBCs) during storage, which can affect their viability, impact blood flow, decrease oxygen delivery, and increase the
generation of potentially harm waste particle.

A

Storage Lesion

22
Q

Enumerate Changes During Storage

A

Decreased pH, Decreased ATP, Decrease Potassium, Decreased 2,3 DPG, Decrease Glucose

Build up of Lactic Acid, Increased potassium in plasma

23
Q

Acid Citrate Dextrose storage time (Days):

A

21 days

24
Q

For each 100mL of blood how many mL of ACD solution needed

A

15mL

25
Q

Citrate Phosphate Dextrose storage time(days):

A

21 days

26
Q

For each 100mL of blood, how many CPD Solution is added

A

14mL

27
Q

Storage time for CPDA-1

A

35 days

28
Q

Chemical in anticoagulants solutions wherein, this is the substrate for ATP production

A

Dextrose

29
Q

Chemical in anticoagulants solutions wherein, Production of ATP (extends shelf-life
from 21 to 35 days).

A

Adenine

30
Q

This chemicals in anticoagulants solutions maintains pH during storage necessary for maintenance of adequate levels of 2,3 DPG

A

Monobasic sodium phosphate

31
Q

This chemicals in anticoagulant chelates calcium and prevents clotting

A

Citrate (Sodium citrate)

32
Q

Additives is introduced by

A

Hogman and Lovric

33
Q

Adsol (Fenwal Lab) also known as?
And state its abbreviation

A

Baxter, AS-1

34
Q

Nutricel ( Medsep Corp) also known as
State its abbreviation

A

Pall Corporation, AS-3

35
Q

Optisol also known as
State its abbreviation

A

Terumo Corporation, AS-5

36
Q

Transcribe PIGPA

A

Phosphate, Inosine, Glucose, Pyruvate and Adenine

37
Q

In red cell freezing, Addition of cryoprotective agent to red cells to prevent what

A

Prevent lysis of red cells due to crystal formation

38
Q

Random donor platelet is prepared from

A

Whole Blood

39
Q

Single donor platelet is prepared from

A

Apheresis

40
Q

Liquid Plasma is recovered from

A

Expiry whole blood

41
Q

Useful burn patients because of their ability to rapidly cross the capillary membrane and increase the plasma volume.

A

Crystalloids

42
Q

Used as volume expanders in
hemorrhagicshockandburn patients

A

Colloids

43
Q

Hereditary AT deficiency in connection with surgical or obstetrical procedures or for those suffering from thromboembolism.

A

ANTITHROMBIN III CONCENTRATE

44
Q

there is a ______ spin to produce platelet-rich plasma and packed RBCs

A

Light

45
Q

Changes during storage

A

Decrease: glucose, pH, ATP, 2,3 DPG
Increased: Lactic acid, potassium in plasma

46
Q

Removal of glycerol by washing RBCs with decreasing concentration of saline

A

12%-1.6%-0.9% NaCI

47
Q

Random donor platelet storage is

A

5 days, 22-24C with constant agitation

48
Q

Single donor platelet (prepared through apheresis) storage

A

5 days, 22-24C with constant agitation

49
Q

Fresh frozen plasma is prepared from whole blood within

A

6 hours

50
Q

Shelf life of CPDA-1

A

35 days