Blood Components

Question 1

Whole blood is collected in a ratio of _____ of anticoagulant preservative for every _____ of whole blood targeted for collection.

Answer 1

14mL, 100 mL

Question 2

The inability or insufficient production of specific blood components of the body leads to

Answer 2

Coagulopathy, and Thrombocytopenia

Question 3

Three main benefit of component Theraphy

Answer 3

Limit the risk of transfusion reaction and overload

Targets the condition or deficiency

Assures the quality of the specimen

Question 4

This blood components Contains RBC and plasma, with hematocrit level of 38%
- Indication: for increasing both the blood volume and RBC mass
- Collected by venipuncture into blood
specific blood components
insufficient production of
coagulopathy and thrombocytopenia
bags with
preservatives
- Volume: 450-500 mL

Answer 4

Whole Blood

Question 5

This blood components 80% of plasma is removed

Additive solutions: 50 mL of plasma can be removed in exchange for 150 mL of adenine-saline

Volume: 250-300mL

Answer 5

Packed RBC

Question 6

The product most often transfused
during the neonatal period or in infants younger than 4 months of age

• Very small amount is transfused specially in neonates (10 to 25 mL)
• Anticoagulant: CPDA01

Answer 6

RBC Aliqouts

Question 7

What is the only FDA approved solution in rejuvenated rbc

Answer 7

Rejuvesol

Question 8

RBC LEUKOREDUCED is prepared by

Answer 8

Filtration, Sedimentation and Saline Washing

Question 9

Also known as random-donor platelets

Answer 9

Platelet Concentrate

Question 10

Can be used to supply transfusions to several neonates or infants

Answer 10

Platelet Aliquots

Question 11

This plasma derivatives indicates hemophilia A, factor VII deficiency

Answer 11

Activated Factor VII

Question 12

This plasma derivatives indicates hemophilia A and classical hemophilia

Answer 12

Factor VIII Concentrate

Question 13

This plasma derivatives, significant levels of vitamin K dependent factors: II, VII, IX, X

Answer 13

Factor IX concentrates

Question 14

This plasma derivatives, Factor XIII deficiency - severe autosomal-recessive bleeding disorder associated with neonatal hemorrage and a lifelong bleeding diathesis

Answer 14

FACTOR VIII-CONCENTRATES

Question 15

This plasma derivatives, Indication: Immunodeficiency diseases, passive antibody prophylaxis

Answer 15

Immune serum globulin

Question 16

This plasma derivatives, Prepared from salvaged plasma

Answer 16

Normal serum albumin

Question 17

This plasma derivatives, Similar to that of NSA, with fewer purification steps
- Contraindication: infusion during cardiopulmonary bypass procedures

Answer 17

Plasma protein fraction

Question 18

This plasma derivatives Indications: Hereditary AT deficiency in connection with surgical or obstetrical procedures or for those
suffering from thromboembolism.

Answer 18

Antithrombin III Concentrate

Question 19

For irradiated blood components use what

Answer 19

Cesium 137, and Cobalt 60

Question 20

Platelet rich plasma can be subjected wit what type of spin (hard/light)

Answer 20

Hard Spin

Question 21

refers to the changes that occur in red blood cells (RBCs) during storage, which can affect their viability, impact blood flow, decrease oxygen delivery, and increase the
generation of potentially harm waste particle.

Answer 21

Storage Lesion

Question 22

Enumerate Changes During Storage

Answer 22

Decreased pH, Decreased ATP, Decrease Potassium, Decreased 2,3 DPG, Decrease Glucose

Build up of Lactic Acid, Increased potassium in plasma

Question 23

Acid Citrate Dextrose storage time (Days):

Answer 23

21 days

Question 24

For each 100mL of blood how many mL of ACD solution needed

Answer 24

15mL

Question 25

Citrate Phosphate Dextrose storage time(days):

Answer 25

21 days

Question 26

For each 100mL of blood, how many CPD Solution is added

Answer 26

14mL

Question 27

Storage time for CPDA-1

Answer 27

35 days

Question 28

Chemical in anticoagulants solutions wherein, this is the substrate for ATP production

Answer 28

Dextrose

Question 29

Chemical in anticoagulants solutions wherein, Production of ATP (extends shelf-life from 21 to 35 days).

Answer 29

Adenine

Question 30

This chemicals in anticoagulants solutions maintains pH during storage necessary for maintenance of adequate levels of 2,3 DPG

Answer 30

Monobasic sodium phosphate

Question 31

This chemicals in anticoagulant chelates calcium and prevents clotting

Answer 31

Citrate (Sodium citrate)

Question 32

Additives is introduced by

Answer 32

Hogman and Lovric

Question 33

Adsol (Fenwal Lab) also known as? And state its abbreviation

Answer 33

Baxter, AS-1

Question 34

Nutricel ( Medsep Corp) also known as State its abbreviation

Answer 34

Pall Corporation, AS-3

Question 35

Optisol also known as State its abbreviation

Answer 35

Terumo Corporation, AS-5

Question 36

Transcribe PIGPA

Answer 36

Phosphate, Inosine, Glucose, Pyruvate and Adenine

Question 37

In red cell freezing, Addition of cryoprotective agent to red cells to prevent what

Answer 37

Prevent lysis of red cells due to crystal formation

Question 38

Random donor platelet is prepared from

Answer 38

Whole Blood

Question 39

Single donor platelet is prepared from

Answer 39

Apheresis

Question 40

Liquid Plasma is recovered from

Answer 40

Expiry whole blood

Question 41

Useful burn patients because of their ability to rapidly cross the capillary membrane and increase the plasma volume.

Answer 41

Crystalloids

Question 42

Used as volume expanders in hemorrhagicshockandburn patients

Answer 42

Colloids

Question 43

Hereditary AT deficiency in connection with surgical or obstetrical procedures or for those suffering from thromboembolism.

Answer 43

ANTITHROMBIN III CONCENTRATE

Question 44

there is a ______ spin to produce platelet-rich plasma and packed RBCs

Answer 44

Light

Question 45

Changes during storage

Answer 45

Decrease: glucose, pH, ATP, 2,3 DPG Increased: Lactic acid, potassium in plasma

Question 46

Removal of glycerol by washing RBCs with decreasing concentration of saline

Answer 46

12%-1.6%-0.9% NaCI

Question 47

Random donor platelet storage is

Answer 47

5 days, 22-24C with constant agitation

Question 48

Single donor platelet (prepared through apheresis) storage

Answer 48

5 days, 22-24C with constant agitation

Question 49

Fresh frozen plasma is prepared from whole blood within

Answer 49

6 hours

Question 50

Shelf life of CPDA-1

Answer 50

35 days