Blood Cell Disorders

Question 1

bruton’s agammaglobulinnemia

Answer 1

decrease B-cells
decreased IgG
m/c primary immunodeficiency at birth
x-linked

Question 2

DiGeorge

Answer 2

hypoplasia of thymus= primary T-cell deficiency at birth

Question 3

Burkett’s Lymphoma

Answer 3

starry sky appearance
central africa
jaw swelling
young african child

Question 4

Hodgkin’s

Answer 4

Pel Epstein fever
biopsy: Reed Sternberg cells
enlarged lymph nodes
hepatosplenomegal

Question 5

Multiple Myeloma

Answer 5

leukemia of bone marrow
affects plasma cells
age 50+
example of non-hodgkin lymphoma
see cancer notes on multiple myeloma

Question 6

severe combined immune deficiency

Answer 6

bubble boy
newborn without proper B or T-cells
problem with bone marrow
in adult, m/c due to APLASTIC ANEMIA
possibly from benzene poisoning