Blood Flashcards
Barbara Herlihy. (2020). The Human Body in Health and Illness (7th Edition) [Texidium version]. Retrieved from http://texidium.com Conestoga College. (2025, February 5). Blood [PowerPoint slides]. eConestoga.
What is the study of blood?
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Hematology
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What are the blood’s three general functions?
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Transport
Regulation
Protection
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What delivers oxygen (O2) and nutrients to every cell in the body?
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Blood
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What picks up the cell’s waste material and delivers it to organs that eliminate it from the body?
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Blood
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What is used as a vehicle for nutrient, ion, and hormone movement throughout the body?
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Blood
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What participates in fluid and electrolyte balance regulation, acid–base balance, and body temperature?
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Blood
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What helps protect the body from infection?
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Blood
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What contains clotting factors, which help protect the body from excessive blood loss?
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Blood
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Which connective tissue contains blood cells dispersed within a liquid intercellular matrix?
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Blood
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What causes the difference in blood colour?
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Oxygen (O2)
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What colour is well-oxygenated blood?
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Red
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What colour is oxygen (O2)-poor blood?
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Blue
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The average adult has ___ to ___ L of blood.
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4
6
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Which blood characteristic is normal at 7.35 to 7.45?
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pH
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What refers to blood thickness and affects the ease with which blood flows through the blood vessels?
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Viscosity
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What is best demonstrated by comparing the flow of water and molasses?
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Viscosity
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Blood is normally three to five times more ___ than water.
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viscous
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What blood’s two components?
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Plasma
Formed Elements (Blood Cells and Cell Fragments)
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Which component is a pale-yellow fluid composed mostly of water?
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Plasma
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Which component contains proteins, ions, nutrients, gases, and waste?
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Plasma
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What consists of albumin, clotting factors, antibodies, and complement proteins?
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Plasma Proteins
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What helps to regulate fluid volume, protects the body from pathogens, and prevents excessive blood loss in the event of injury?
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Plasma Proteins
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What is the plasma minus the clotting proteins?
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Serum
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What three components do blood cells and cell fragments include?
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Red Blood Cells (RBC)
White Blood Cells (WBC)
Platelets
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What are red blood cells (RBCs) called?
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Erythrocytes
Eythro, meaning “red”.
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Which cells are primarily involved in oxygen (O2) transport to all body tissues?
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Red Blood Cells (RBC)
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What are white blood cells (WBC) called?
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Leukocytes
Leuko, meaning “white”.
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Which cells protect the body from infection?
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White Blood Cells (WBC)
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What are platelets called?
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Thrombocytes
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Which cells protect the body from bleeding?
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Platelets
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The two blood parts can be observed in a test tube.
If a blood sample is collected in a tube and spun in a centrifuge, two phases appear: the heavier ___ ___ appear at the bottom of the tube; the lighter ___ accumulates at the top.
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blood cells
plasma
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Which test is the separation of blood into two phases?
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Hematocrit (Hct)
Packed Cell Volume
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Which test is the blood cell percentage in a blood sample?
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Hematocrit (Hct)
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A sample of blood is normally composed of ___% blood cells and ___% plasma.
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45
55
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Of which blood cell type is the hematocrit (Hct) blood cell component mainly composed?
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Red Blood Cells (RBC)
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What is the small layer of cells between the plasma and the red blood cells (RBC) in a hematocrit (Hct)?
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Buffy Coat
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Which hematocrit (Hct) component consists of white blood cells (WBC) and platelets?
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Buffy Coat
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What hematocruit (Hct) generally interpreted by because the buffy coat is so thin?
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Red Blood Cells (RBC)
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What is a person with a low hematocrit (Hct) [lower number of red blood cells (RBC) than normal] considered?
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Anemic
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What does any change in blood volume affect?
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Hematocrit (Hct)
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When a dehydrated patient has a diminished blood volume, the ratio of red blood cells (RBC) to blood volume (decreases/increases).
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increases
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Elevated hematocrit (Hct) represents not an increase in red blood cells (RBC), but a decrease in __ ___.
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blood volume
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What does expanded blood volume, as occurs in heart failure, decrease?
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Hematocrit (Hct)
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A lowered hematocrit (Hct) represents not a decrease in red blood cells (RBC), but an increase in ___ ___.
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blood volume
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Which anemia does expanded blood volume cause?
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Dilutional
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Hematocrit (Hct)
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What is the blood cell formation process?
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Hemopoiesis
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In which tissue are red blood cells (RBC), white blood cells (WBC), and platelets made?
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Hemopoietic
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What are the two hemopoietic tissue types in the adult?
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Red Bone Marrow
Lymphatic
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What is red bone marrow blood formation?
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Myeloid Hemopoiesis
Myeloid comes from the Greek word meaning “bone marrow.”
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What is lymphatic tissue blood formation?
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Lymphoid Hemopoiesis
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DELETE DUPLICATE
What is lymphatic tissue blood formation?
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DELETE DUPLICATE
Lymphatic Hemopoiesis
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What is found primarily in long bone end’s, such as the femur, and in flat and irregular bones, such as the sternum, cranial bones, vertebrae, and bones of the pelvis?
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Red Bone Marrow
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Where are the three different blood cell types produced?
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Red Bone Marrow
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By which red bone barrow cell are the three different blood cell types produced?
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Stem
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Which cell differentiates into a red blood cell (RBC), white blood cell (WBC), or platelet under specific growth factor influences?
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Stem
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Which two blood cells originate in the bone marrow?
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Lymphocytes
Monocytes
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In which tissue do some lymphocytes mature and reproduce?
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Lymphatic
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Which large blood cell breaks up into tiny cell fragments called platelets or thrombocytes?
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Megakaryocyte
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What is bone marrow depression?
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Myelosuppression
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What leads to a severe deficiency of red blood cells (RBC), causing a serious form of anemia called aplastic anemia?
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Myelosuppression
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What causes a deficiency of white blood cells (WBC) (leukocytes) called leukopenia?
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Myelosuppression
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Which myelosupressive condition may cause a person to be more prone to infection and to die from a common cold?
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Leukopenia
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Which myelosuppresive condition leads to inadequate platelets or thrombocytes production numbers?
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Thrombocytopenia
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Which myelosupressive condition may cause risk for bleeding or hemorrhage?
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Thrombocytopenia
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What do many drugs, especially cytotoxic cancer drugs, radiation, and a variety of diseases cause?
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Myelosuppression
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What is hyperactive bone marrow or overactivity and excess blood cell production?
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Polycythemia Vera
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What causes thickened blood (increased viscosity) that burdens the heart, overwhelms the clotting system, and produces a beet-red, ruddy face?
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Polycythemia Vera
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What are the most numerous blood cells at 4.5 - 6.0 million in 1 μL (microliter) of blood and a production rate of several million per second?
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Red Blood Cells (RBC)
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What is red blood cell (RBC) production?
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Erythropoiesis
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Which blood cells are primarily concerned with oxygen (O2) and carbon dioxide (CO2) transport?
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Red Blood Cells (RBC)
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Into which cells do stem cells within the red bone marrow differentiate?
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Proerythroblast
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Into which cell does a proerythroblast eventually mature?
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Erythrocyte (RBC)
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What is an immature red blood cell (RBC)?
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Reticulocyte
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What can develop into mature red blood cells (RBC) within 48 hours of release into the blood?
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Reticulocytes
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Which blood cell count is normally very small (0.5% to 1.5%)?
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Reticulocyte
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Which red blood cell (RBC) may indicate blood loss or an iron-deficient state when high in numbers?
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Reticulocyte
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What might a low reticulocyte count indicate?
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Myelosuppression
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Which blood cells are so large that they are unable to wiggle through the walls of the blood vessels?
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Red Blood Cells (RBC)
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Which blood cells stay in the blood vessels and do not roam around tissue spaces?
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Red Blood Cells (RBC)
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Which blood cells are flexible, disc-shaped cells that have a thick outer rim and a thin center?
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Red Blood Cells (RBC)
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What do red blood cells (RBC) do to squeeze through tiny blood vessels called capillaries?
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Bend
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Which blood cell’s flexibility allows oxygen (O2) delivery to every cell in the body?
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Red Blood Cells (RBC)
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Which cell disease includes decreased oxygenation and cell death?
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Sickle Cell
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In which disease do the red blood cells (RBC) assume a C shape and block blood flow through the tiny blood vessels instead of bending?
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Sickle Cell
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EDIT PICTURE
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Edit picture
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What refers to unequal-sized red blood cells (RBC)?
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Anisocytosis
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What refers to irregularly shaped red blood cells (RBC)?
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Poikilocytosis
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Which two red blood cell (RBC) shapes are found in anemia and other blood disorders?
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Anisocytosis
Poikilocytosis
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What is a cell than is smaller than normal like in iron deficiency anemia?
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Microcytic
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What is a cell that is larger than normal like in vitamin B12 deficiency anemia?
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Macrocytic
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Which term describes a pale coloured red blood (RBC)?
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Hypochromic
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Which term decribes a normal coloured red blood cell (RBC)?
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Normochromic
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Which term decribes a deeper red red blood cell (RBC)?
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Hyperchromic
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Which blood cell normally loses almost all its organelles as it matures?
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Red Blood Cell (RBC)
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Which term describes how a red blood cell (RBC) produces adensoine triphosphate (ATP) without a mitochondira?
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Anaerobic
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What term describes the phenomenon where red blood cells (RBC) do not use (metabilize) the oxygen (O2) they are transporting throughout the body?
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Anaerobic
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What do red blood cells (RBC) lack, in addition to DNA, that prevents them from replicating?
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Nucleus
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Which blood cells are not replicated and instead replaced by new cells when removed from the blood?
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Red Blood Cells (RBC)
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Which large protein molecule fills red blood cells (RBC)?
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Hemoglobin
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What are hemoglobin’s two parts?
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Globin
Heme
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Which substance is globin?
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Protein
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Which substance does heme contain?
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Iron
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Hemoglobin contains four ___ chains, each having a ___ group.
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globin
heme
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Which molecule is responsible for red blood cell (RBC) function?
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Hemoglobin
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As red blood cells (RBC) circulate through the lung’s blood vessels, ___ attaches loosely to the ___ atom in the___.
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O2
iron
heme
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What is oxygenated hemoglobin?
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Oxyhemoglobin
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As the blood flows to various body tissues, the ___ detaches from the hemoglobin.
The unloaded ___ diffuses from the blood to the cells, where it is used during cellular metabolism.
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oxygen (O2) x 2
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Which hemoglobin portion transports some of the carbon dioxide (CO2) from its production site in metabolizing cells to the lungs, where it is excreted?
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Globin
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What is the CO2-hemoglobin complex?
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Carbaminohemoglobin
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Which molecule plays a role in gas transport?
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Hemoglobin
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What is blood’s colour when hemoglobin is oxygenated?
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Red
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What is blood’s colour when hemoglobin is unoxygenated?
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Blue
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What is blood’s colour coming from the lungs?
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Red
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What is blood’s colour leaving the tissues?
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Blue
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Which condition includes blue looking skin from oxygen (O2) deprivation?
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Cyanosis
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Which condition includes cyanosis as a sign?
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Hypoxemia
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