Blood Flashcards
Functions of blood
Transportation
Regulation
Protection
Transportation
Oxygen, carbon dioxide, nutrients, waste products, hormones
Regulation
Maintains body temp
Maintains normal pH in body tissue
Protection
Controls bleeding (clotting process)
Defends from infection
Components of blood
Plasma (55%)
Formed elements (45%)
Plasma
Clear , extraceular matrix
Proteins, nutrients, electrolytes, hormones and gases
Albumin- main protein in blood
Formed elements
Cells and cell fragments
Erythrocytes (red blood cells or RBC)
Leukocytes (white blood cells)
Platelets (thrombocytes)
Hemopoesis
Formation of blood cells
Red bone marrow; produces all types of blood cells
Lymphatic tissue; produced lymphocytes
Red blood cells
Deliver oxygen to cells
Remove carbon dioxide
Shaped for optimum gas exchange
Hemoglobin
Groups of protein chains (globin) with iron containing heme bound to them
Oxygen binds to the heme and is transported through the body
When the oxygen is released, carbon dioxide bonds to the globin to go back to the lungs for release
What is the extraceullur matrix of blood
Plasma
Erythropoietin (EOP)
Red blood cells
Hormone produced and released by the kidneys
When RBC are low EPO stimulate the bone marrow to make more erythrocytes
When RBC are old, the liver and spleen destroy them and break up their components
Red blood cell life cycle
O2 levels decrease
Kidneys secrete erythropoietin
Bone marrow creates erythrocytes
Reticulocytes are released, they mature into RBC
O2 levels increase ; EOP and RBC production decrease
Breakdown of RBC
Macrophages in liver and spleen ingest and destroy old RBC
Globin
Amino acids (Caries carbon dioxide)
Heme
Iron and bilirubin (Caries oxygen)
White blood cells
-Leukocytes
-Protect the body against pathogens (disease causing viruses)
-granulocytes
Agranulocytes
Granulocytes
Neutrophils, eosinophils(red stain), and basophils(take the blue in colour)
Agranulocytes
Lymphocytes and monocytes
Basophils
Involved in secreting heparin and histamine
Eosinophils
Involved in allergic reactions; kill parasites
Neutrophils
Migrate out of blood vessels to engulf and digest foreign material
Most abundant WBC
Lymphocytes
T lymphocytes are involved in attacking infected or cancerous cells
B lymphocytes produce/forming antibodies to specific antigens
Monocytes
Migrate into tissues to become macrophages that ingest bacteria, cellular debris and cancerous cells