Block 7 Flashcards
Langerhans histiocytosis: eos gran vs Hand Schuller vs Letterer Siwe dz. markers?
children bone vs 3ad: exophthalmos, scalp lesions, DI vs diffuse/severe, skin & cystic bone lesions. CD1a/207, S100
JAK2: polycythemia vera vs essential thrombocythemia vs PMF
erythralgia, thrombosis; high H&H & RBC, low EPO; tx phlebotomy, hydroxyurea vs thrombosis; high megakaryocytes/PLT vs dacrocytes, dry tap
lichen planus assoc w/ what pathogen? erythema multiform assoc w/ what pathogens?
HCV. HSV1 & myco pneu
nonmegalo: Diamond Blackfan anemia
congen RBC aplasia -> short, triphalangeal, craniofacial abnl; tx corticosteroids, transfusion, HCT
details PNH vs G6PD vs PKD
venous thrombosis, tx ecluzimab blocks C5 -> chk gono; sucrose vs abd pain, know triggers; Heinz/bite/degmacytes vs AR PKLR 1q21; echino/burr, inc rigidity & 2,3 BPG; mitivapat
details vit K defic vs AT defic. heparin-induced thrombocytopenia vs warfarin-induced nec vs neonatal purpura fulm
inc PT/INR vs nephrotic/hypercoag vs PLT dec >50%, tx protamine vs too low C/S, tx LMWH or FFP vs homozygous for C/S defic
details AML vs APML vs ALL vs CML vs CLL vs HCL
pancyto vs MPO/Auer, CD13/33, cyto granules, bilobed nucleus vs medistinal mass; imat vs low LAP, imat vs N/A vs cladrobine
details follicular lymphoma vs mantle cell vs DLBCL vs Burkitt vs Hodgkin
no BCL2, yes macs; LAD vs tx -zomib vs B sxs vs c-myc, CD21 vs cerv LAD/mediastinal mass, B sxs
AL vs AA vs ATTR vs dialysis vs ApoA-I amyloid
RCM vs acute phase reactant vs WT in heart vs bone vs renal
psoriasis
hyper/parakeratosis, hypervasc dermal papillae, acanthosis, inc corneum/spinosum, dec granulosum
details AIP vs PCT. Glanzmann vs Bernard vs ASA vs uremia
abd pain vs excess hair growth. no GPIIb/IIIa -> no PLT aggreg vs no GP1b -> no adhesion vs no aggreg & activation vs no aggreg & adhesion
