Block 6 Flashcards
abiraterone, spirono, ketoconazole vs fluta/bicalutamide vs danazol
inhib 17a hydroxylase & 17,20 lyase. spirono also impair testo to its receptor vs nonsteroidal antiandrogen for prostate ca vs synthetic androgen tx endometriosis & hereditary angioedema
oligo vs polyhydramnios. fetal alc syndrome
Potter, placental insuff, renal & sacral agen vs anenceph, no swallowing center, eso/duo atresia. heart/lung fistula, TE fistula, holoprosenceph
hypopit: Sheehan vs Empty Sella vs pit apoplexy
dec bloodflow to pit pp vs compressed or atrophied pit vs pit hem
hypogly. Cushing syndrome sxs
tremor, tachy, anxiety, hunger, AMS, sz; tx w/ simple carbs, IV glucagon, IV dextrose. inc chol, inc urine cortisol, inc sugar, HTN, immunosuppress, neoplasm causes, growth retard, skin changes, moon facies, buffalo hump, centripetal fat
neuroblastoma vs pheo
n-myc, adrenal med in peds, +Bombesin & NSE, dx high metanephrines vs episodic sxs, adrenal med in adults, dx urin metanephrines & catechol, tx phenoxybenzamine -> BB -> surg
insulinoma vs glucagonoma vs somatostatinoma
Whipple 3ad, high C-peptide, MEN1, tx surg vs dermatitis, diarrhea, dep, decline wt, DM, DVT; tx octreo, surg vs achloride, gallstones, steatorrhea, DM; tx surg, octreo
carcinoid tumor
neuroendo cells; flush, wheeze, telangiectasia, RHF/tricuspid/pulm, pellagra. tx surg, octreo, telotristat/trp hydroxylase inhibitor. rule of 1/3
cinaclet vs sevelamer.
-ozole
activate Ca2+ sensing receptor -> dec PTH prod VS dec PO4 absorption. aromatase inhib to tx ER+ brca
M3 vs B3 vs alpha 1 on micturition. which nn for erect vs emission vs expulsion?
ctx bladder vs relax bladder vs ctx prostate & bladder neck smooth mm. pelvic splanchnic nn S2-4 vs hypogastric nn T11-L2 vs pudendal nn (visceral/somatic)
causes of renal vs bladder vs urethral injury
trauma, low rib fx vs sup injury from full bladder; ant injury from pelvic fx vs ant from straddle -> scrotal hematoma; post from pelvic fx
placental aromatase defic vs 5a-reductase defic vs supine hypotensive syndrome
viril of preg pt/females b/c high testo vs ambig genitals till puberty when testo inc vs preg in supine -> gravid ut on IVC -> dec venous return
cryptoorchidism
undescended testes; abd, inguinal, ectopic; impaired spermatogen, inc risk germ cell tumors. tx orchiopexy
hyperPRL can dec what hormone? endometroid vs serous endomet ca
GnRH -> dec LH & testo. unopposed estrogen; loss PTEN or MMR genes vs endometrial atrophy; Psammoma, papillae, tufts
how to tx vasa previa? endometriosis vs endometritis
emergency c/s. endomet glands/stroma outside endometrium; tx NSAIDS, ocp, danazol vs retain prod post delivery, miscarriage, ab, foreign body; tx genta + clinda +/- amp
leiomyoma vs leiomyosarcoma
high estrogen, smooth mm vs PMP, in myometrium
Cushing causes
exog -> adrenal atrophy
1o adrenal adenoma/ca -> unilat hyperplasia
ACTH adenoma (Cushing dz) -> bil adrenal hyperplasia
