Bipolar Affective Disorder Flashcards

1
Q

ICD classification of bipolar

A

hypomania
mania with psychotic features
mania without psychotic features

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2
Q

onset of bipolar

A

late teens/ early 20s

FH often results earlier

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3
Q

what is BAD defined as?

A

two or more episodes where the patient’s mood/ activity are significantly disturbed, consisting of hypomania or mania and depression

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4
Q

presentation of hypomania

A

mood elevated to concerning degree and sustained for at least 4 days with at least 3 of:

  • increased activity/ restless
  • increased talkativeness
  • difficulty concentrating
  • decreased need for sleep
  • increased sexual energy
  • mild spending sprees or other types of reckless behaviour
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5
Q

presentation of mania

A

mood elevation sustained for at least 1 week (or severe enough to require hospital admission)

  • hypomania symptoms
  • flight of ideas or experience of thoughts racing
  • loss of social inhibitors/ inappropriate behaviour
  • grandiosity
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6
Q

diagnosis of BAD

A

MSE
psychotic symptoms= delusions/ hallucinations
co-morbdities

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7
Q

MSE associations with bipolar/ mania

A
bright clothes
distractibility
overfamiliarity
increased talkativeness
punning and clang associations
increased thought flow
flight of ideas
loosening of associations
grandiosity
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8
Q

bipolar I

A

mania + depression

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9
Q

bipolar II

A

hypomania + depression

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10
Q

co-morbidities in bipolar

A
anxiety
substance misuse
personality disorder
eating disorder
schizophrenia
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11
Q

maintenance management options for BAD

A
  1. lithium

2. ECT

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12
Q

acute mood stabilisers in BAD

A

anticonvulsants
antipsychotics (FIRST LINE)
BZDs
antidepressants

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13
Q

what is lithium

A

an element so is not subject to metabolism and excreted by the kidneys
indistinguishable from Na+ so risks dehydration

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14
Q

normal side effects of lithium

A
strange taste
polydipsia
polyuria
tremor
hypothyroid
reduced renal function
nephrogenic DI
weight gain
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15
Q

toxic side effects of lithium

A
D&V
coarse tremor
altered consciousness
drowsy
convulsions
coma
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16
Q

how often is ECT undertaken?

A

twice a week

17
Q

what is ECT

A

electricity given to achieve a seizure lasting 15-30s that is monitored with EEG
done under general anaesthetic and muscle relaxant

18
Q

what is done if ECT seizure is prolonged?

A

stopped with BZDs

19
Q

side effects of ECT

A

autographical memory

20
Q

anticonvulsants used in BAD

A

valproic acid
lamotrigine
carbamazepine

21
Q

examples of antipsychotics

A

quetiapine
aripiprazole
olanzapine
lurasidone

22
Q

action of antipsychotics

A

dopamine and serotonin antagonists

23
Q

side effects of antipsychotics

A

sedation
weight gain
metabolic syndrome
extra-pyramidal side effects

24
Q

when are BZDs used?

A

symptom control

25
Q

when should antidepressants be prescribed?

A

not without a antimanic drug

SSRI is first line