Biostatistics Flashcards
Crush this shit
Number of “new” cases/number of people at risk of acquiring that disease
Incidence
Total number of cases (new + old)/whole population
Prevalence
What is the importance of incidence?
Acute cases, e.g., incidence of Zika virus infection in August
Attack rate
is the number of people with disease over the number of people at risk for the disease.
What is the significance of prevalence?
Chronic cases only,a e.g., prevalence of diabetes in United States
Identifies all patients with the disease, and if negative, can virtually rule out the diagnosis.
Sensitivity
When you lower the cut off point you are ______ more patient with the disease?
including
When you increase the cut off you are ______ more patient
excluding
Sensitivity and (PPV or NPV) go with one another?
NPV, and this is because as we lower the cut off this increases the amount true positives lowering the FN (increasing the NPV) and vice versa if we increase the cut off the TP go down and FN increases (decreasing the NPV)
Specificity and (PPV or NPV) go together?
Specificity goes with PPV, as the cut off increases the TN go up and the false positives go down (PPV increases) and vice versa if the cut off were to decrease
This is a rare disease reporting
with illustrative images, treatment, and follow-up.
Case report
This study is Snapshot of present time uses surveys to identify current health problems.
Cross sectional
Study that starts with a risk factor and observes for disease development. The group is divided into exposed and unexposed.
cohort
Starts with disease and identifies risk factors. Group is composed of patients with and without disease and mutual risk factors
Case control
What is the weakness of a cohort?
Attrition (loss of study participants) or migration, selection bias is built in, confounding bias