BIORISK MANAGEMENT (ppt) Flashcards
Containment principles, technologies and practices that are implemented to prevent UNINTENTIONAL exposure to BIOLOGICAL AGENTS or their inadvertent release.
biosafety
Principles, technologies and practices that are implemented for the PROTECTION, CONTROL and ACCOUNTABILITY of BIOLOGICAL MATERIALS and/or the equipment, skills and data related to their handling
biosecurity
- ______ – protecting people form BAD BUGS
- _______– protecting BAD BUGS from BAD PEOPLE
BIOSAFETY, BIOSECURITY
An object or situation that has the potential to cause adverse effects when an organism, system or (sub)population is exposed to it.
hazard
A combination of the likelihood of an incident and the severity of the harm (consequences) if that incident were to occur.
risk
A systematic process of gathering information and evaluating the likelihood and consequences of exposure
to or release of workplace hazard(s) and determining the appropriate risk control measures to reduce the risk to an acceptable risk.
risk assessment
Part of risk assessment where the likelihood of exposure to a hazard is weighed against the potential severity of harm under a set of predefined circumstances, such as a specific laboratory procedure
risk evaluation
The risk associated to biological toxins or infectious agents.
biorisk
is the integration of biosafety and biosecurity to manage risks when working with biological toxins and infectious agents (CWA 15793 Laboratory Biorisk Management Standard)
biorisk management
“a system or process to control SAFETY and SECURITY risks associated with the handling or storage and disposal of biological agents and toxins in laboratories and facilities.
Biorisk Management (BRM)
What defined biorisk management?
CEN Workshop Agreement (CWA) 15793:2011
encompasses the identification, understanding, and management aspects of a system in interrelated processes.
biorisk management
3 primary component of biorisk management
- assessment
- mitigation
- performance
- A framework that integrates BEST PRACTICES and PROCEDURES
- Ensures that an organization can effectively achieve all of its OBJECTIVES
- Frequently built around the Plan, Do, Check Act cycle
CWA 15793:2011
- identification of potential for improvement
- analysis of current situation
- development of new concepts
- hazard identification, risk assessment
Plan
- testing and optimization of new concepts by basic means at one working place
- Policy
- procedures
- programs
Do
- careful checking of process and obtained results
- if successful → full approval as a standard process
- monitoring audit
Check
- full implementation as a standard which is periodically checked by audits
- corrective/preventive action
Act
The AMP model is like three-legged stool. What symbolizes:
* seat
* three legs
- seat: biorisk management
- three legs: assessment, mitigation, performance
Identification of hazards and characterization of risks
risk assessment
refers to anything in the environment that has a potential to cause harm while
hazard
generally defined as the possibility that something bad or unpleasant (such as injury or loss) will happen.
risk
4 steps of risk assessment?
- Define the situation
- Define the risks
- Characterized the risks
- Determine if risks are acceptable or not
Steps in risk assessment:
- Identification of hazards and risks of the biological agents
- Humans and animals inside or outside the laboratory
- Work activities and laboratory environment including location, procedures and equipment
define the situation
Review of how individuals inside and outside the laboratory may be exposed to the hazards.
define the risk
step in risk assessment:
Risk assessment team needs to compare the LIKELIHOOD and the CONSEQUENCES of infection
characterize the risk
step in risk assessment:
Evaluating the BioRisk arising from a biohazard take into account the adequacy of any existing controls,
determine if risks are acceptable or not
measures are actions and control measures that are put into place to reduce or eliminate the risks associated with biological agents and toxins
biorisk mitigation
- In the bottom of the hierarchy of controls
- considered as least effective
- protect the worker
Personal protective equipment (PPE)
In the hierarch of controls:
* Change the way people work
* 2nd least effective
administrative control
- in the middle of the hierarchy of control
- “isolate people from the hazard”
engineering controls
- 2nd most effective in the hierarchy of controls
- “replace the hazard”
substitution
- considered the most effective, and at the top, of the hierarch of controls
- “physically remove the hazard”
Elimination
- Involves a systematic process intended to achieve organization objectives and goals.
- Helps to highlight BioRisk strategies that are not working effectively and measures that are ineffective or unnecessary.
- A reevaluation of the overall mitigation strategy.
performance evaluation
