Biology Chapter 3: Molecular Genetics Flashcards

1
Q

Difference between eukaryotes and prokaryotes: RNA polymerase

A

Eukaryotes: have RNA polymerase I, II, II whereas prokaryotes just have RNA polymerase

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2
Q

3’ poly A tail purpose

A

Anti degradation in cytoplasm

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3
Q

Splicesomes are found in the

A

Nucleus

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4
Q

What is splicing

A

Non coding sequences are removed and coding sequences ligated

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5
Q

Does siRNA exert transcriptional control or post-transcriptional control

A

Post-transcriptional control.

siRNA can only bind to other RNA strands NOT DNA or protein

Therefore, it must interfere with gene expression after transcription has already occurred, but before translation. Specifically, it prevents the translation of mRNA corresponding to the target protein.

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6
Q

Viable trisomies

A

Trisomy 21, 18, and 13

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7
Q

Acrocentric chromosomes

A

have the centromere near one end, resulting in a very short p arm and a long q arm, often containing repetitive DNA and ribosomal RNA genes

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8
Q

Translocation

A

chromosomal abnormality where a segment of one chromosome is transferred to another chromosome

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9
Q

Cell differentiation is mediated primarily by:

A

gene expression levels.

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