Biology Chapter 3: Molecular Genetics Flashcards
Difference between eukaryotes and prokaryotes: RNA polymerase
Eukaryotes: have RNA polymerase I, II, II whereas prokaryotes just have RNA polymerase
3’ poly A tail purpose
Anti degradation in cytoplasm
Splicesomes are found in the
Nucleus
What is splicing
Non coding sequences are removed and coding sequences ligated
Does siRNA exert transcriptional control or post-transcriptional control
Post-transcriptional control.
siRNA can only bind to other RNA strands NOT DNA or protein
Therefore, it must interfere with gene expression after transcription has already occurred, but before translation. Specifically, it prevents the translation of mRNA corresponding to the target protein.
Viable trisomies
Trisomy 21, 18, and 13
Acrocentric chromosomes
have the centromere near one end, resulting in a very short p arm and a long q arm, often containing repetitive DNA and ribosomal RNA genes
Translocation
chromosomal abnormality where a segment of one chromosome is transferred to another chromosome
Cell differentiation is mediated primarily by:
gene expression levels.