Biological Treatments Flashcards

1
Q

what are the 2 different treatments

A
  • typical antipsychotics
  • atypical antipshycotics
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2
Q

what are the 3 different antipsycotics

A
  • chlorpromazine (typical)
  • clozapine
  • risperidone
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3
Q

how does chlorpromazine work

typical

A
  • blocks dopamine D2 receptors which recuces dopamine activity
  • reduces positive symptoms
  • worsens negative symptoms
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4
Q

how does clozapine work

A
  • weakly blocks dopamine receptors which reduces dopamine activity
  • strongly blocks serotonin receptors which helps balance DA
  • some patients died of blood clotting
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5
Q

how does risperidone work

A
  • blocks dopamine receptors but more selective resulting in fewer movement side effects
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6
Q

give two positives on the use of antipsychotics

A
  • cost effective
    • impact on economy
  • ethical - ppl live independantly
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7
Q

give two negatives on the use of antipsychotics

A
  • ethics - some treatments do more harm than good
  • outdated - rely on outdated version of dopamine hypothesis
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8
Q

give 2 studies involving the effectiveness of antipsychotics

postitive

A
  • bugnall - meta anaylsis of 232 studies comparing typical and atypical. atypical more effective
  • thornly et al - chlorpromazine reduced symptom severity compared to placebo
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9
Q

give a study involving the effectiveness of antipsychotics

negative

A
  • healy - most studies focus on the short term effects which may be due to the calming effects of the drug
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10
Q

what is a major side effect of chlorpromazine

A

tardive dyskenisia - face spasms

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11
Q

give a PEELH on the use of antipsychotics

weakness

A
  • P - side effects
  • Eg - chlorpromazione, tardive dyskenisia
  • Ex - further problems
  • L - goes against protection from harm
  • H - some more side effects than others, choice makes a difference
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12
Q

give a PEELH on the use of antipsychotics

strength

A
  • P - effective
  • Eg - thornly et al, reduced symptopms severity compared to placebo
  • Ex - reduces symptoms
  • L - improve quality of life
  • H - must be taken everyday, can be a hinderence
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