biofilm and diet Flashcards
what are the early colonizers
streptococcus salivarius, streptococcus mitis, streptococucs oralis
with time gram-negative anaerobes appear what are they
prevotella melaninogenica, fusobacterium nucleatum, veillonella spp.
resident microflora prevent overgrowth of pathogenic organisms by
-saturation of microbial attachment sites
-effective competition w essential nutrients
-creating unfavorable conditions to invading microbes
-production of inhibitory factors
pellicle formation what time
within minutes
attachment of early colonizers what time
0-24hrs
microcolony formation by co-adhesion and growth
4-24hrs
species diversity through microbial succession
1-7 days
mature biofilm
1 week or older
what is the bridging organism between early and late colonizers
F. nucleatum
predominance by what gram is in 5 days
gram -
rapid colonization by pioneer species are what
gram + cocci and rods
biofilm composed of microcolonies (how much volume) distributed in shaped matrix (how much volume)
microcolonies (15-20% volume)
shaped matrix (75-80% volume)
has voids and water channels also
what is the backbone of biofilm
exopolysaccharides (EPS)
normal microflora of fissures is sparse or dense, and favored metabolism is derived from what
sparse
sugar breakdown (saccharolytic metabolism)
what dominates in fissures
streptococci, w few gram - or anaerobic organisms