Biochem recap Flashcards
t/f anabolic pathways synthesise oxidised products from small reduced precursors
false
t/f anabolic pathways require the input of reducing force in the form of NADPH
true
t/f catabolic pathways generate reduced cofactors which can drive oxidative phosphorylatioin
true
t/f glycolysis occurs in the mitochondrial matrix
false
what is generated in the breakdown of glucose
pyruvate
2 NADH and 2 H+
what are the rate limiting catalysts in glycolysis 3
Hexokinase
Phosphofructokinase
Pyruvate kinase
t/f pyruvate is converted to oxaloacetate and is used for fatty acid degradation
false
converted to acetyl-Coa and enters TCA
t/f TCA cycle occurs in mitochondrial matrix
true
in oxidative phosphorylation, what is required for the synthesis of ATP
proton flow
outline proton flow in oxidative phosphorylation
protons pumped into intermembrane space from inner mitochondrial membrane
lower pH in intermembrane, and so concentration gradient between the two allows flow back
backward flow drives atp synthase
NADH and FADH2 donate electrons to
Complex I and II respectively
purpose of complexes I, II and IV
pump protons out
transport electrons
what is the p/o ratio
measure of number of ATP molecules formed per oxygen atom reduced
if nadh has a more negative potential than fahd2. this means its transfer of its electrons to oxygen will release less energy
no
does not determine energy produced, just affinity for electrons
t/f a negative redox potential means that the reduced form of X has a lower affinity for electrons than H2
true