Biochem Flashcards
What is the rate limiting step of: glycolysis?
PFK-1
What is the rate limiting step of: gluconeogenesis?
Pyruvate carboxylase
What is the rate limiting step of: TA (Krebs) cycle?
Isocitrate dehydrogenase
What is the rate limiting step of: glycogenesis (glycogen synthesis)
glycogen synthase
What is the rate limiting step of: glycogenolysis
glycogen phosphorylase
What is the rate limiting step of: hexose monophosphate (HMP) shunt
G6PD
What is the rate limiting step of: fatty acid synthesis
Acetyl CoA carboxylase
What is the rate limiting step of: B-oxidation
Carnithine acyltransferase I
What is the rate limiting step of: ketogenolysis
HMG CoA synthase
What is the rate limiting step of: cholesterol synthesis
HMG CoA reductase
What is the rate limiting step of: Urea cycle
Carbomoyl phosphate synthetase I
What is the rate limiting step of: heme synthesis
d-ALA synthase
What is the rate limiting step of: pyrimidine synthesis
Aspartate transcarbomylase
What is the rate limiting step of: purine synthesis
PRPP glutamyl amido transferase
What is the only faty acid that is gluconeogenic?
propionic acid
Aldose reductase converts galactose to what?
galactitol
How many ATPs are generated from glycolysis?
8
In the mito, what complex is needed in order for pyruvate carboylase to catalyze the rxn from pyruvate to OAA?
Biotin, ATP, and CO2
What is the enzyme for the oxidative reaction in glycolysis
Glyceraldehyde dehydrogenase
What 3 substrates control the enzyme PEPCK for the conversion of OAA to pyruvate in the cytoplasm?
What is released from this rxn?
- Cortisol (stimulates PEPCK)
- Glucagon
- Guanin triphosphate (GTP)
CO2
What enzyme deficiency causes cataracts, galactosemia, and galactosuria?
Galactokinase deficiency
Addition of D-2,3-BPG to HbA does what to the O2 saturation curve?
Shift R
What is the glycolysis enzyme found only in the liver?
Glucokinase
How many ATPs are generated per acetyl CoA
12 (Not 15 - that would be the answer if you included the pyruvate to acetyl CoA step)