Basic Principles

Question 1

What are the three hormone subtypes?

Answer 1

Proteins and peptides

Steroids

Tyroine and tryptophan derivatives

Question 2

What are the four basic hormone receptors

Answer 2

G-protein coupled receptors

Receptor Tyrosine Kinase Families

Steroid Hormone receptors

Receptors associated with tyrosine kinase activity

Question 3

What are the main sensors of the internal enviroment?

Answer 3

G-protein coupled receptors

Question 4

Name two receptors which are cytokine receptors (linked to tyrosine kinase activity)

Answer 4

Prolactin receptor

Growth hormone receptor

Question 5

Where do you find steroid hormone receptors?

Answer 5

Intracellular - cytoplasm or nucleus

Question 6

How do steroid hormones bring about change?

Answer 6

Steroid/receptor complex binds to DNA response elements resulting in changes in gene transcription

Question 7

Where does Prolactin come from?

Answer 7

Secreted by Lactotroph cells of the anterior pituitary

Question 8

How is prolactin production controled ?

Answer 8

under tonic inhibition by hypothalamic dopamine