Basic Pharmacology Flashcards
antibiotic
-used for bacterial infection
black box warning
- state potential new and life-threatening risks of taking specific medications
- given by FDA
brand names
- some brand names dont have a generic
- there can be multiple brands for a generic
albuterol
-bronchodilator
amlodipine besylate
- antihypertensive
- calcium channel blocker
amoxicillin
antibiotic
aripiprazole
antipsychotic
atorvastatin
- antilipemic
- statin
azithromycin
antibiotic
celecoxib
anti-inflammatory
cephalexin
antibiotic
ciprofloxacin
antibiotic
clopidogrel
antiplatelet
donepezil
anti-alzheimers
duloxetine
antidepressant
enoxaparin
anticoagulant
escitalopram
antidepressant
esomeprazole
anti-ulcer agent
-proton pump inhibitor
fenofibrate
antilipemic
fluticasone/salmeterol
antiasthma
- glucocorticoid
- bronchodilator
furosemide
diuretic
gabapentin
anticonvulsant
hydrochlorothiazide
diuretic
hydrocodone plus acetaminophen
opioid (narcotic) analgesic
insulin
hypoglycemic
levofloxacin
antibiotic
levothyroxine
thyroid hormone
lisinopril
antihypertensive
-ACE inhibitor
losartan
antihypertensive
memantine
anti-alzheimers
metformin
hypoglycemic
methylphenidate
central nervous system stimulant
metoprolol succinate
antihypertensive
-beta blocker
metoprolol tartrate
antihypertensive
-beta blocker
montelukast
bronchodilator
-leukotriene inhibitor
olanzapine
antipsychotic
omeprazole
anti-ulcer agent
-proton pump inhibitor
oxycodone
opioid (narcotic) analgesic
pioglitazone
hypoglycemic
pravastatin
antilipemic
-statin
prednisone
glucocorticoid
pregabalin
anticonvulsant
quetiapine
antipsychotic
rosuvastatin
antilipemic
-statin
sildenafil
erectile dysfunction agent
simvastatin
antilipemic
-statin
sulfamethoxazole/trimethoprim
antibiotic
tramadol
analgesic
valsartan
antihypertensive
warfarin
anticoagulant
zolpidem
sedative-hypnotic (for sleep)
amp
ampule
cap
capsule
cr
cream
elix
elixir
liq
liquid
lot
lotion
sup
suppository
- small, solid, cylinder
- insertion into rectum or vagina
syr
syrup
tab
tablet
ung
ointment
C
cup, Celsius
ds
double strength
g, gm
gram
gr
grain
gtt
drop
kg
kilogram
L
liter
lb
pound
mcg
microgram
mEq
milliequivalent
mg
milligram(s)
mg/dL
milligrams per deciliter
oz
ounce
qt
quart
tbsp
tablespoon
tsp
teaspoon
ID
intradermally
IM
intramuscularly
inj
inject, injection
IV
intravenously
PO
by mouth, orally
PR
rectally
r, rec
rectally
subcut
subcutaneously
top
topically
a
before
ac
before meals
ad lib
as desired
AM
morning
bid
twice a day
line over c
with
d
daily, day
h, hr
hour
noct
night
pc
after meals
PM
evening, nighttime
PRN
whenever necessary
q
every
qam
every morning
q4h
every 4 hours
qid
4 times per day
stat
immediately
ut dict
as directed
agit
shake, stir
aq
water
ASA
aspirin
cmpd
compound
DAW
dispense as written
dil
dilute
disp
dispense
eq
equivalent
ext
extract
Fe
iron
gen
generic
H2O
water
K
potassium
MDI
metered-dose inhaler
med
medicine
MO
mineral oil
neb
nebulizer
NKA
no known allergies
NPO
nothing by mouth (nil per os)
N/V
nausea/vomiting
OTC
over-the-counter
O2
oxygen
nr
no refills
per
by means of, through
qs
sufficient amount
rept
repeat
rf
refill(s)
rx
prescription, treatment
line over s
without
sig
write on the label
susp
suspension
-dissolves
sx
symptoms
tinc
tincture
-medicinal preparation in an alcohol base
TO
telephone order
tx
treatment
VO
verbal order
US Drug Enforcement Administration (DEA)
- designates medications into 5 schedules
- 5 schedules- potential for abuse or dont have medical use
5 schedules
- sorted by therapeutic action, chemical formulation, body system, symptoms they relieve
- a medication can be in more than one category
gabapentin and pregabalin
- anticonvulsants but also analgesics
- relieve seizures and neuropathic (nerve) pain
hydrochlorothiazide
- diuretic
- antihypertensive
analgesics
relieve pain
- acetaminophen
- hydrocodone
antacids/anti-ulcer
neutralize stomach acid
- esomeprazole
- calcium carbonate
antibiotics
kills bacteria
- amoxicillin
- ciprofloxacin
anticholinergics
reduce bronchospasm
- ipratropium
- dicyclomine
anticoagulants
delay blood clotting
- warfarin
- enoxaparin
- heparin
anticonvulsants
prevent or control seizures
- clonazepam
- phenytoin
- gabapentin
antidepressants
relieve depression
- doxepin
- fluoxetine
- duloxetine
- selegiline
antidiarrheals
reduce diarrhea
- bismuth subsalicylate
- loperamide
antiemetics
reduce nausea, vomiting
- metoclopramide
- ondansetron
antifungals
kill fungi
- fluconazole
- nystatin
- micronazole
antihistamines
relieve allergies
- diphenhydramine
- cetirizine
- luratadine
antihypertensives
lower blood pressure
- metoprolol
- lisinopril
- valsartan
- clonidine
anti-inflammatories
reduce inflammation
- ibuprofen
- celecoxib
- naproxen
antilipemics
lower cholesterol
- atorvastatin
- fenofibrate
antimigraine agents
relieve migraine headaches
- topiramate
- sumatriptan
anti-osteoporosis agents
improve done density
- alendronate
- ibandronate
- calcitonin
antipsychotics
- control psychotic symptoms
- quetiapine
- haloperidol
- risperidone
antipyretics
reduce fever
- acetaminophen
- ibuprofen
- aspirin
antispasmodics/muscle relaxants
reduce or prevent muscle spasms
- cyclobenzaprine
- methocarbamol
antitussives/expectorants
control cough, promote elimination of mucus
- dextromethorphan
- codeine
- guaifenesin
antivirals
kill viruses
- acyclovir
- interferon
- oseltamivir
anxiolytics (antianxiety)
reduce anxiety
- clonazepam
- diazepam
- lorazepam
bronchodilators
relax airway muscles
- albuterol
- isoproterenol
- theophylline
central nervous system stimulants
reduce hyperactivity
- methylphenidate
- modafinil
contraceptives
prevent pregnancy
- medroxyprogesterone
- acetate
- ethinyl estradiol
decongestants
relieve nasal congestion
- pseudoephendrine
- mometasone
diuretics
eliminate excess fluid
- furosemide
- hydrochlorothiazide
hormone replacement
stabilize hormone deficiencies
- levothyroxine
- insulin
- desmopressin
- estrogen
laxatives, stool softeners
promote bowel movements
- magnesium hydroxide
- bisacodyl
oral hypoglycemics
reduce blood glucose
- metformin
- acarbose
- glyburide
sedative-hypnotics
induce sleep/relaxation
- zolpidem
- temazepam
- eszopiclone
Controlled Substances Act (CSA)
- 5 schedules
- controlled substances according to potential abuse and addiction
Schedule 1
- high potential for abuse
- no approved medical use in US (cant be prescribed)
- illegal
- heroin, mescaline, lysergic acid diethylamide (LSD)
- cannabis (in some states)
Schedule 2
- high potential for abuse
- considered dangerous and can lead to psychological and physical dependence
- morphine, methadone, oxycodone, hydromorphone, hydrocodone, fentanyl, methamphentamine
- hand written prescriptions
- no refills
- secure, locked cabinet storage
Schedule 3
- moderate to low potential for physical and psychological dependence
- ketamine, anabolic steroids, testosterone
- handwritten prescription
- may refill 5 times within 6 months
Schedule 4
- substances that have low potential for abuse and dependence
- diazepam, zolpidem, eszopiclone, alprazolam, chlordiazepoxide, clonazepam
- sign prescription
- refill 5 times in 6 months
- authorize refills over phone
Schedule 5
- contain limited quantities of some narcotics
- antidiarrheal, antitussive, analgesic
- diphenoxylate with atropine, pregabalin, lacosamide, opium/kaolin/pectin/belladonna
- sign prescriptions
- refill 5 times in 6 months
- authorize over phone
therapeutic effects
-the good effects of medication
adverse event
- unintended, harmful reaction to medications
- allergic reaction
- prevents further use
contraindication
-symptoms or condition that makes a particular treatment or medication inadvisable or even dangerous
precautions
-problems that pose a lesser risk but require close observation and monitoring during medication therapy
indication
-the indication for an antihypertensive drug (for ex.) is high blood pressure
side effects
- develop predictably and unavoidably
- not necessarily harmful
- ex. side effect to antihistamine is sleepiness
- different from adverse effects
contraindication
- specific situation in which a drug should not be used because it may be harmful to the person
- most common contraindication is hypersensitivity (previous allergic rxn)
- another contraindication is how a medication reacts with certain foods and other medications
length measurement
-use for some creams
micro
1/1000000 of base unit
milli
1/1000 of base unit
centi
1/100 of base unit
base unit
1
kilo
x1000 of base unit
apothecary measurements
- 15 grains= 1,000 mg
- 1 minim = 1 drop
- 1 dram = 60 minims = 1 tsp = 5 mL
mg to mcg
.008 mg = 88 mcg
-x1000
dosage calculation: formula method
desired / have
-what to give divided by what you have
pediatric dosage
-use weight calculations
body surface area (BSA)
- most accurate way to calculate dose based on weight for children up to age 12
- calculate BSA with a nomogram
- (childs dose (BSA) x adult dose)/1.7 meters^2
aerosols
inhalation
caplets
oral
capsules
oral
creams
topical, vaginal, rectal
drops
otic, ophthalmic, nasal
dry powder for inhalation
inhalation
elixirs
oral
emulsions
oral
foams
vaginal
gels
oral, topical, rectal
injectable liquids
IV, IM, subcut, ID
liniments
topical
lotions
topical
lozenges
oral
mist
inhalation, nasal
ointments
topical, ophthalmic, otic, vaginal, rectal
patches
topical (transdermal)
powders
topical
powders for reconstitution
IV, IM, subcut, ID
solid extracts, fluid extracts
oral
solutions
oral, topical, vaginal, urethral, rectal (enemas)
sprays
topical, nasal, inhalation, sublingual
steam
inhalation
suppositories
vaginal, rectal
suspensions
oral
syrups
oral
tablets
oral, buccal, sublingual, vaginal
tinctures
oral, topical
route of administration
- included on every prescription
- two routes:
- enteral- through GI
- parenteral- outside GI tract
parenteral route
- outside GI tracts
- epidural
- intra-arterial
- intra-articular
- intradermal
- intramuscular
- intraosseous
- intraperitoneal
- intrapleural
- intrathecal
- intravenous
- subcutaneous
enteral route
- through GI tract
- buccal
- oral
- sublingual
other routes of administration
- nasal
- ophthalmic
- otic
- rectal
- respiratory/inhaled
- topical/transdermal
- vaginal
- urethral
- not enteral or parenteral route
pharmacokinetics
- how medications move through the body
- onset activity, peak time, duration
- absorption
- distribution
- metabolism
- excretion
absorption
- body converts medication and streams in blood
- liquids absorb faster
- varies with route -> IV goes directly into blood -> quicker
- all medications end up in blood
- how easily the medication dissolves in fat plays a role
- surface area available for absorption (intestines are faster than stomach)
distribution
- transportation of medication
- bloodstream -> to organs
- blood brain barrier protects
- passes placental barrier easily -> this is why its risky for pregnant pts to take
metabolism
- changes active forms of medication into harmless metabolites ready for excretion
- liver, kidneys
- age, genetics, # of medications, health affect this
- dosages are modified for infants and older people to compensate for metabolism variation
excretion
- removal of medication metabolites from body
- kidneys -> urine
- feces, saliva, bile, sweat glands, breast milk, exhaled air
- medications half life is how long it takes for processes of metabolism and excretion to eliminate half a dosage
rights of medication administration
- right patient- 2 pt identifiers
- right medication- check 3 times
- right dose
- right time
- right route
- right assessment- ask about allergies
- right to refuse
- right documentation- document when you administer
- right to know- inform about medication
physician desk reference
- available each year
- current detailed information about medication