basal gg

Question 1

Basal gg (made up of) = ____ + ______

Answer 1

striatum + globus pallidus

Striatum contains:
o Caudate -< nucleus accumbens>- putamen
o Nucleus accumbens is where the caudate and putamen meet

Globus pallidus :
o Globus pallidus external (aka lateral)
o Globus pallidus internal (aka medial)

Question 2

lentiform nucleus (made up of) = ______+_______

Answer 2

putamen + globus pallidus

Question 3

Substantia nigra (made up of) = ______+ _____

Answer 3

pars compacta + pars reticulate

Question 4

cc: ________: where dopamine neurons are located

Answer 4

pars compacta

cc: the part that dies in parkinson’s

Question 5

_______: help to move the eyes back and forth

Answer 5

pars reticulata

Question 6

name the (3) portions of the basal gg

Answer 6

archaestriatrum
paleostriatum
neostriatum

Question 7

Within the archaestriatum the _____ is located. This structure holds emotions like fear/aggression/ rage . located in the temporal lobe

Answer 7

amygdala

Question 8

_____& _____ are held in the paleostriatum.

What separates these 2 structures

Answer 8

caudate and putamen

internal capsule separates them
nucleus accumbens

Question 9

basal gg is at the center of the ______

Answer 9

telencephalon

Question 10

** Cortex and basal gg communicate with ea. other ____

Answer 10

ipsi

Cortex and basal gg communicate with the M contralateral

Question 11

**Cortex and basal gg communicate with the M _________

Answer 11

contralateral

** Cortex and basal gg communicate with ea. other ipsi

Question 12

** berebellum communicates with the M ____

Answer 12

ipsi

Question 13

Cortical input gives off _____

Answer 13

glutamate

Basal gg input gives off GABA-ergic
Midbrain nuclei input gives off Dopaminergic

Question 14

Basal gg input gives off____

Answer 14

GABA

Cortical input gives off glutamate
Midbrain nuclei input gives off Dopaminergic

Question 15

Midbrain nuclei input gives off____

Answer 15

dopaminergic

Cortical input gives off glutamate
Basal gg input gives off GABA-ergic

Question 16

List the Basal gg structure pathway

Answer 16

striatum –> globus pallidus –> VA/VL complex of Thalamus –> UMN in cortex

Question 17

_____ neurons are inhiboitory cells located in the striatum

Answer 17

Medium spiny neurons

Question 18

Medium spiny neurons receive axons from____

project to___

Answer 18

receive: Cortex & substantia nigra pars compacta
project: GPi & SNpr

Question 19

______: controls eyes through inhibition of the superior colliculus

Answer 19

SNpr

Question 20

SNpr controls eyes through the inhibition of the ____

Answer 20

superior colliculus

Question 21

GPi projects to the _________ of the thalamus

Answer 21

ventral anterior/ventral lateral complex (VA/VL)

Question 22

____ structure works with the motor cortex to kick starts the striatum in the direct basal gg pathway

Answer 22

sunstantia nigra pars compacta

Question 23

substantia nigra pars compacta acts on the ___ receptor to effect the striatum

Answer 23

D1

w/ dopamine

Question 24

striatum acts on the ___ receptor to stim the GPi

Answer 24

D2

releases GABA

Question 25

cc: W/o the _________ Parkinson pt’s only use the motor cortex to make movements

Answer 25

substantia nigra pars compacta

Question 26

the ______ stops the direct pathway circuit

Answer 26

cerebellum

Question 27

cc : lesion in the striato-thalamo-cortical pathway causes____
what pathway is this ?

Answer 27

direct pathway

causes bradykinesis

Parkinsons: there is a lesion so that substantia nigra pars compacta can not assist the motor cortex to start the striatum

Question 28

Dopamine from the SNpc is _____ in the direct pathway

Answer 28

excitatory

-D1 receptors

Question 29

Dopaminefrom the SNpc is _____ in the indirect pathway

Answer 29

inhibitory

-D2 receptors