1. Neurodevelopment part 1 Flashcards
half the _____ genes are involved in the development of the NS
protein coding genes
most neuronal production and migration occurs during the ___ through ___ mo. of development
3rd- 5th mo.
the formation of neural connections called ____ and myelin sheaths conti after birth
neuropil
gliogenesis takes place during the ___ and ___ trimesters of pregenancy and early postnatal development
2nd and 3rd tri
_____ occurs during the morula stage
totipotent
_____ occurs during the late blastocyst stage
pluripotent
____ is the ability of a single cell to divide and produce all of the differentiated cells in an organism,
totipotency
_______:a stem cell that has the potential to differentiate into any of the three germ layers
pluripotent
___derm gives rise to the NS and skin
ectoderm
____derm gives rise to the skeleton and musculature
mesoderm
also known as the notochord
___derm gives rise to the gut tube
endoderm
_____ : process of forming the neural tube from ectoderm
neuralation
______: how neural tis becomes differ. tiss
neural induction
______ provides neural inducing morphogens to the ectoderm
mesoderm
_______: is a bone morphogenic signal that makes ectoderm skin
BMP
the ____ blocks the signalling from BMP so that ectoderm will become neural tis instead
of skin
notochord
_______: a specific signal that decides the fate of a differentiating cell
amorphagen
(3) factos that are involved during neurulation
- formation of neural plate
- neural plates become neural groove surrounded by crest
- groove becomes closed neural tube
c.c. ____ : results from incomplete caudal neural tube closure
spina bifida
c.c. _______: spina bifida that results in the meninges + CSF being enclosed in a sac
meningocele
c.c. ______: spina bifida that results in the SC, meninges and CSF enclosed in a sac
meningomyelocele
more dangerous
c.c._______: is spinda bifida that has a piece of tiss that covers the open area
spina bifida occulta
c.c. ______: results from incomplete rostral neural tube closure
anencephaly
c.c._______: brain that doesnt have meninges over it
encephalocele
_____ is a supp. that mothers can take to helps the neural tube to close
folate
the neural tube closes around the ___ wk
3wk
_____= forebrain
prosecephalon
___= midbrain
mesencephalon
____= hindbrain
rhombencephalon