Barrett's Oesophagus Flashcards
1
Q
Description: What is Barrett’s oesophagus?
A
Type of glandular metaplasia where squamous epithelium is replaced by metaplastic glandular columnar epithelium
2
Q
Aetiology: What causes Barrett’s oesophagus?
A
Prolonged acid exposure in the distal oesophagus
3
Q
Pathology: Describe the basic pathology of Barrett’s oesophagus.
A
Squamous epithelium is replaced by metaplastic glandular columnar epithelium containing goblet cells which secrete mucus in the lower oesophagus
4
Q
Treatment: What is the treatment of Barrett’s oesophagus (high grade dysplasia)?
A
- Radio-frequency ablation (RFA)
- Endoscopic Mucosal Resection (EMR)
- Oesophagectomy (rarely done)
5
Q
Complications: What is the major complication of Barrett’s oesophagus?
A
- Oesophageal adenocarcinoma (occurs after dysplasia)
6
Q
Investigations: What investigation is done for Barrett’s Oesophagus?
A
- Upper GI endoscopy with biopsy
