Bacterial Infections of the Pregnant Uterus Flashcards

1
Q

What are the consequences of infection of the reproductive tract in female and males?

A

Female:

  • Endometritis
  • Metritis
  • Infertility
  • Abortion

Males:

  • Prostatitis
  • Orchitis
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2
Q

What are the 3 sources of infection of the reproductive tract?

A
  1. Venereal e.g. CEM
  2. Endogenous infection e.g. S zooepidemicus
  3. Environmental e.g. B licheniformis
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3
Q

What bacteria are associated with infections of the reproductive tract?

A
Beta-haemolytic strep
Leptospira interrogans
Salmonella dublin and spp.
Listeria monocytogenes
Chlamydophila abortus
Campylobacter fetus venerealis
Campylobacter fetus fetus
E coli
Klebsiella pneumoniae
Bacillus licheniformis
Taylorella equigenitalis
Brucella abprtos
Mycoplasma spp.
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4
Q

What fungi are associated with infection of the reproductive tract?

A

Aspergillus
Mucor
Others…

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5
Q

What are the major bacteria pathogens causing bovine abortion?

A
Leptospira hardjo
Salmonella dublin
Bacillus licheniformis
Brucella abortis
Mycoplasma
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6
Q

What does Leptospira hardjo causes? What is the reservoir? How do we diagnose?

A

Bovine abortion, infertility and milk loss
Reservoir: cattle and sheep co-grazing/water/introduction of new animals/shared bull
Diagnose: paired serology

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7
Q

What type of pathogen is Bacillus licheniformis and what does it cause?

A

Spore forming areobic, gram +ve rod

Sporadic abortion - from the environment so opportunisitic

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8
Q

Where is Brucella abortus present?

A

Eradicated in the UK
Present in Ireland and Europe
Persistent in parts of the world

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9
Q

What does Brucella abortis cause?

A

Zoonotic - undulant fever in humans
Chronic infections: granulomatous lesions
Migration to placenta
Placentitis causes abortion

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10
Q

What stain do we use for Brucella abortis?

A

Koster’s stain

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11
Q

What type of bacterial is Brucella abortis?

A

Delicate gram -ve coccobaccilus

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12
Q

What type of bacteria is Salmonella dublin and what stain do we used?

A

Group D salmonella
Invasive, bloodborne invasion of placenta
XLD medium

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13
Q

What is bovine infectious infertility?

A

Caused by Campylobacter fetus venerealis

On MM and prepuce of mature bull as lifelong asymptomatic infection

Infection of the cow causes catarrhal inflammation of the genital tract

This causes endometritis and inflammation

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14
Q

How do we detect bovine infectious infertility?

A

Campylobacter venerealis
MM and prepuce of mature bull
Detect by culture:
Sheath washing or products of abortion

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15
Q

What is bovine endometritis?

A

Inflammation of the uterine mucosa

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16
Q

What causes non-specific postpartum endometritis in the cow? What can the infection continue to become?

A

Trueperella pyogenes
E coli
Enterococcus faecalis
Anaerobes

Bovine pyometra

17
Q

What are the main bacterial pathogens causing ovine abortion?

A
Chlamydophila abortus
Campylobacter series
Toxoplasma species
Salmonella species
Listeria spp.
Salmonella dubline
Coxiella spp.
Yersinia pseudotuberculosis
18
Q

What type of pathogen is Chlamydophila abortus? What does it cause?

A
Enzootic abortion in sheep
Obligate intracellular pathogen
Persistent infection
Late pregnancy abortion in ewes
Subsequent fertility NOT imparied
19
Q

What is the reservoir for Chlamydophila abortus? What detection and prevention is there?

A

Sheep infection, faeces, birds
Venereal or oral transmission
Antigen detection by ELISA or Koster’s stain
Vaccination prevents new cases by does not clear established infection

20
Q

What is Koster’s stain?

A

Modified ZN

Weak carbol fuschin followed by 5% acetic acid then methylene blue

21
Q

How do Chlamydophila appear in Kosters’ stain?

A

Red against blue

22
Q

How does Campylobacter fetus fetus cause abortion in sheep?

A

10% of ovine abortions (sporadic)

Resrvoir:

  • GI
  • Ingestion
  • Invasion
  • Blood
  • Bacteraemia
  • Placenta
  • Abortion
23
Q

What causes pyometra and endometritis in canines?

A

Coliforms (E. coli)

Strep canis, zooepidemicus

24
Q

What causes prostatitis in canines?

A

E. coli
Proteus
Staph and strep
Mycoplasma felis

25
Q

What bacteria causes abortion in mares?

A

Strep zooepidemicus

26
Q

What is CEM?

A

Contagious equine metritis
Caused by Taylorella equigenitalis
Acute, contagious venereal disease
(Metritis, cervicitis, discharge)

27
Q

What bacteria causes metritis in mares?

A

Klebsiella pneumoniae

Pseudomonas aeruginosa