Bacteria list for Final Flashcards
Chlamydias (4)
- Gram-negative
- Pleomorphic (Cocci on exam)
- Obligate intracellular parasites
- similar to Rickettsias
Chlamydia trachomatis: (4)
- most common sexually transmitted bacterial disease in the US
- cause of eye infections and STDs
- enters through breaks in skin or mm
- no vaccine available
Antibiotic for Chlamydia trachomatis:
Tetracycline
Diseases caused by Chlamydia trachomatis: (3)
- Nongonococcal urethritis (NGU) in Males
- Pelvic inflammatory disease (PID) in Females
- Lymphogranuloma venereum –> infects lymphnodes and obstructs them that causes the formation of buboes in the inguinal region
Pseudomonas sp.
- Gram-negative Rod, Environmental (found in soil, water, and on plants; opportunistic pathogen in humans, especially in immunocompromised individuals)
Legionella pneumophila (5)
- Gram-negative, Rod
- Causes Legionnaires’ disease and Pontiac fever
- found in water, and soil, particularly in cooling towels, hot tubs, air conditioning systems, water heaters, and shower heads
- must live in association with protozoa
- infection occurs from inhalation of aerosols
Alveolar macrophages
- Phagocytizes L. pneumophilia but cannot kill it
- multiplies inside the cell as an intracellular parasite
Pontiac fever: (2)
- Mild symptoms from L. pneumophilia, includes; a fever, chills, cough, and body aches
- some may not experience any symptoms at all
Legionnaires disease: (3)
- Severe pneumonia caused by L. pneumophilia that includes; high fevers, chills, a cough, body aches, mental confusion, and impaired respiration
- Untreated mortality rate = 25%
- most at risk: smokers, D, transplant Pts on immunosuppressants, and the elderly
Antibiotic for Legionella pneumophilia: (3)
- Erythromycin
- chlorination of cooling towers and artificial habitats can keep aerosols low
- no vaccination available
Pseudomonas aeruginosa (2)
- Introduced through caths/injections, wounds, or burns
- found all over hospitals in ventilators, humidifiers, and bathrooms
Diseases caused by Pseudomonas aeruginosa: (3)
- Exotoxins can cause UTIs
- ear/eye infections
- Can cause septicemia (–> endocarditis, meningitis, and pneumonia)
Pseudomonas (7)
- Gram-negative bacilli
- metabolically versatile as to C source
- found in soil
- Opportunistic pathogen especially in nosocomial infections
- very resistant to soaps, detergents, disinfectants
- many drug-resistant strains
- no immunization available
Staphylococcus: (6)
- Gram (+) cocci in grape clusters
- Facultative anaerobes
- Catalase positive
- can withstand high pH, high salt, dry conditions, and high temperatures
- > 30 species
- found on skin and mm of warm-blooded animals
Staphylococcus aureus: (2)
- MOST IMPORTANT in this group
- Many virulence factors including; coagulase, staphylokinase, hyaluronidase, nucleases, lipase, penicillinase, hemolysins, leukocidin, enterotoxins, exfoliative toxin, protein A, TSS toxin
Coagulase:
- causes the coagulation of blood plasma –> puts a layer of fibrin around cells –> which protects them from phagocytosis
- from S. aureus and S. intermedius (pathogen in dogs)
Staphylokinase:
- activates plasminogen (blood plasma protein) to plasmin (protease) that digests fibrin in clots
Hyaluronidase:
- digests hyaluronic acid that binds together connective tissue to allow invasion of tissues
Nucleases:
digests DNA and RNA
Lipase:
allows staphylococci to colonize oily skin surfaces
Penicillinase:
destroys penicillins
Hemolysisns:
lyses RBCs
Leukocidin:
lyses WBCs
Enterotoxins:
damages intestinal epithelial cells causing water and electrolyte loss (secretory diarrhea)
Exfoliative toxin:
causes loss of epidermal layer of skin
Protein A:
a cell wall-associated protein that binds antibody molecules (IgG) and incapacitates them
TSS toxin (toxic shock syndrome): (3)
- some strains produce a potent toxin that causes a fever, rash, v, liver damage, renal failure
- found in the nasal cavity of everyone but especially infects the vagina from ultra absorbent tampons
- the tampons absorb a large amount of Mg irons, leading to heavy colonization.
Campylobacter jejuni
Gram-negative, Curved (comma-shaped) rod, Animal (primarily poultry; causes foodborne illness in humans)
Neisseria meningitidis
Gram-negative, Cocci (diplococci), Human (respiratory tract; causes meningitis and sepsis)
Actinomyces spp.
Gram-positive, Rod (filamentous, branching), Human (commensal organism in the mouth and gastrointestinal tract; causes actinomycosis)
Clostridium botulinum
Gram-positive, Rod (anaerobic, spore-forming), Environmental (found in soil, improperly canned food; causes botulism)
Mycoplasma pneumoniae
No cell wall, Pleomorphic (variable shape, often appearing as a fried egg), Human (respiratory tract; causes walking pneumonia)
Listeria monocytogenes
Gram-positive, Rod, Environmental (found in soil, water, and decaying plant material; can contaminate dairy products and meats; causes listeriosis)
Bacillus cereus
Gram-positive, Rod (spore-forming), Environmental (soil and food; causes foodborne illness, particularly in rice and leftovers)
Bacillus megaterium
Gram-positive, Rod (spore-forming), Environmental (soil; non-pathogenic, used in biotechnology)
Streptococcus mutans
Gram-positive, Cocci (in chains), Human (oral cavity; causes dental cavities)
Morganella morganii
Gram-negative, Rod, Human (normal intestinal flora, but can cause infections when the normal flora is disrupted)
Streptococcus pyogenes
Gram-positive, Cocci (in chains), Human (throat, skin; causes strep throat, impetigo, and scarlet fever)
Bacillus subtilis
Gram-positive, Rod (spore-forming), Environmental (soil; used in industrial applications)
Clostridium perfringens
Gram-positive, Rod (anaerobic, spore-forming), Environmental (soil and decaying meat; causes gas gangrene and food poisoning)
Bordetella pertussis
Gram-negative, Rod, Human (respiratory tract; causes whooping cough)
Yersinia pestis
Gram-negative, Rod, Animal (primarily rodents; transmitted by fleas; causes bubonic plague)
Bacillus anthracis
Gram-positive, Rod (spore-forming), Animal (infects herbivores, particularly cattle, sheep; causes anthrax)
Clostridium tetani
Gram-positive, Rod (anaerobic, spore-forming), Environmental (soil; causes tetanus)
Escherichia coli
Gram-negative, Rod, Human (normal intestinal flora, but pathogenic strains can cause food poisoning, urinary tract infections)
Corynebacterium diphtheriae
Gram-positive, Rod (club-shaped), Human (respiratory tract; causes diphtheria)
Mycobacterium tuberculosis
Acid-fast (doesn’t stain well with Gram stain), Rod (slow-growing), Human (respiratory tract; causes tuberculosis)
Francisella tularensis
Gram-negative, Rod, Animal (wild animals like rabbits and rodents; causes tularemia)
Helicobacter pylori
Gram-negative, Spiral-shaped (helical), Human (gastric mucosa; causes peptic ulcers)
Coxiella burnetii
Gram-negative, Rod (pleomorphic), Animal (especially cattle, sheep, and goats; causes Q fever)
Rickettsia rickettsii
Gram-negative, Rod (obligate intracellular bacterium), Animal (transmitted by ticks; causes Rocky Mountain spotted fever)
Leptospira interrogans
Gram-negative (spirochete), Spiral (spirochete), Animal (especially rodents; causes leptospirosis)
Brucella abortus
Gram-negative, Rod (coccobacillus), Animal (especially cattle; causes brucellosis)
Treponema pallidum
Gram-negative (spirochete), Spiral (spirochete), Human (sexually transmitted; causes syphilis)
Brucella suis
Gram-negative, Rod (coccobacillus), Animal (especially pigs; causes brucellosis)
Borrelia burgdorferi
Gram-negative (spirochete), Spiral (spirochete), Animal (transmitted by ticks; causes Lyme disease)
Neisseria gonorrhoeae
Gram-negative, Cocci (diplococci), Human (sexually transmitted; causes gonorrhea)
Haemophilus aegyptius
Gram-negative, Rod, Human (causes conjunctivitis and other infections)
Haemophilus ducreyi
Gram-negative, Rod, Human (sexually transmitted; causes chancroid)
Vibrio cholerae
Gram-negative, Comma-shaped rod, Environmental (found in water; causes cholera)
Salmonella typhi
Gram-negative, Rod, Animal (primarily poultry; causes typhoid fever)
Shigella sp.
Gram-negative, Rod, Human (fecal-oral transmission; causes dysentery)
Mycobacterium leprae
Acid-fast (doesn’t stain well with Gram stain), Rod, Human (causes leprosy)
Serratia marcescens
Gram-negative, Rod, Environmental (found in soil, water; opportunistic pathogen in hospitals)
Lactococcus lactis
Gram-positive, Cocci (in chains), Environmental (used in dairy fermentation)
Enterococcus faecalis
Gram-positive, Cocci (in pairs or chains), Human (intestinal tract; can cause urinary tract infections)
Mycoplasma hominis
No cell wall, Pleomorphic, Human (genitourinary tract)
Clostridium difficile
Gram-positive, Rod (spore-forming), Human (intestinal tract; associated with antibiotic-associated diarrhea)
Streptococcus pneumoniae
Gram-positive, Cocci (in pairs, lancet-shaped), Human (normal respiratory flora; causes pneumonia, meningitis)
Lactobacillus acidophilus
Gram-positive, Rod, Human (intestinal and vaginal flora; used in probiotics)
Haemophilus influenzae
Gram-negative, Rod, Human (respiratory tract; causes pneumonia, meningitis)
Citrobacter freundii
Gram-negative, Rod, Environmental (found in water, soil; opportunistic pathogen in humans)
Bacillus thuringiensis
Gram-positive, Rod (spore-forming), Environmental (soil; used as a biological pesticide)
Vibrio parahaemolyticus
Gram-negative, Comma-shaped rod, Environmental (found in seafood; causes food poisoning)
Streptococcus saprophyticus
Gram-positive, Cocci (in clusters), Human (urinary tract; causes urinary tract infections)
Mycoplasma haemophilus
No cell wall, Pleomorphic, Human (rare pathogen, can cause respiratory and genitourinary infections)
Chromobacterium violaceum
Gram-negative, Rod, Environmental (found in soil and water; can cause septicemia)
Micrococcus lactis
Gram-positive, Cocci (in tetrads), Environmental (found on the skin and in milk)
Proteus vulgaris
Gram-negative, Rod, Human (intestinal tract; causes urinary tract infections and wound infections)
Neisseria animaloris
Gram-negative, Cocci (diplococci), Animal (primarily dogs and cats; can infect humans)
Chlamydia pneumoniae (7)
- about 50% of all adults over 50 have antibodies
- 1/2 - 2/3 of MIs may be caused by it
- high amount of antibodies = x4 risk
- reinfection can trigger a MI
- infections contribute to atherosclerosis
- causes a mild pneumonia