Bacteria list for Final Flashcards
Chlamydias (4)
- Gram-negative
- Pleomorphic (Cocci on exam)
- Obligate intracellular parasites
- similar to Rickettsias
Chlamydia trachomatis: (4)
- most common sexually transmitted bacterial disease in the US
- cause of eye infections and STDs
- enters through breaks in skin or mm
- no vaccine available
Antibiotic for Chlamydia trachomatis:
Tetracycline
Diseases caused by Chlamydia trachomatis: (3)
- Nongonococcal urethritis (NGU) in Males
- Pelvic inflammatory disease (PID) in Females
- Lymphogranuloma venereum –> infects lymphnodes and obstructs them that causes the formation of buboes in the inguinal region
Pseudomonas sp.
- Gram-negative Rod, Environmental (found in soil, water, and on plants; opportunistic pathogen in humans, especially in immunocompromised individuals)
Legionella pneumophila (5)
- Gram-negative, Rod
- Causes Legionnaires’ disease and Pontiac fever
- found in water, and soil, particularly in cooling towels, hot tubs, air conditioning systems, water heaters, and shower heads
- must live in association with protozoa
- infection occurs from inhalation of aerosols
Alveolar macrophages
- Phagocytizes L. pneumophilia but cannot kill it
- multiplies inside the cell as an intracellular parasite
Pontiac fever: (2)
- Mild symptoms from L. pneumophilia, includes; a fever, chills, cough, and body aches
- some may not experience any symptoms at all
Legionnaires disease: (3)
- Severe pneumonia caused by L. pneumophilia that includes; high fevers, chills, a cough, body aches, mental confusion, and impaired respiration
- Untreated mortality rate = 25%
- most at risk: smokers, D, transplant Pts on immunosuppressants, and the elderly
Antibiotic for Legionella pneumophilia: (3)
- Erythromycin
- chlorination of cooling towers and artificial habitats can keep aerosols low
- no vaccination available
Pseudomonas aeruginosa (2)
- Introduced through caths/injections, wounds, or burns
- found all over hospitals in ventilators, humidifiers, and bathrooms
Diseases caused by Pseudomonas aeruginosa: (3)
- Exotoxins can cause UTIs
- ear/eye infections
- Can cause septicemia (–> endocarditis, meningitis, and pneumonia)
Pseudomonas (7)
- Gram-negative bacilli
- metabolically versatile as to C source
- found in soil
- Opportunistic pathogen especially in nosocomial infections
- very resistant to soaps, detergents, disinfectants
- many drug-resistant strains
- no immunization available
Staphylococcus: (6)
- Gram (+) cocci in grape clusters
- Facultative anaerobes
- Catalase positive
- can withstand high pH, high salt, dry conditions, and high temperatures
- > 30 species
- found on skin and mm of warm-blooded animals
Staphylococcus aureus: (2)
- MOST IMPORTANT in this group
- Many virulence factors including; coagulase, staphylokinase, hyaluronidase, nucleases, lipase, penicillinase, hemolysins, leukocidin, enterotoxins, exfoliative toxin, protein A, TSS toxin
Coagulase:
- causes the coagulation of blood plasma –> puts a layer of fibrin around cells –> which protects them from phagocytosis
- from S. aureus and S. intermedius (pathogen in dogs)
Staphylokinase:
- activates plasminogen (blood plasma protein) to plasmin (protease) that digests fibrin in clots
Hyaluronidase:
- digests hyaluronic acid that binds together connective tissue to allow invasion of tissues
Nucleases:
digests DNA and RNA
Lipase:
allows staphylococci to colonize oily skin surfaces
Penicillinase:
destroys penicillins
Hemolysisns:
lyses RBCs
Leukocidin:
lyses WBCs
Enterotoxins:
damages intestinal epithelial cells causing water and electrolyte loss (secretory diarrhea)
Exfoliative toxin:
causes loss of epidermal layer of skin
Protein A:
a cell wall-associated protein that binds antibody molecules (IgG) and incapacitates them
TSS toxin (toxic shock syndrome): (3)
- some strains produce a potent toxin that causes a fever, rash, v, liver damage, renal failure
- found in the nasal cavity of everyone but especially infects the vagina from ultra absorbent tampons
- the tampons absorb a large amount of Mg irons, leading to heavy colonization.
Campylobacter jejuni
Gram-negative, Curved (comma-shaped) rod, Animal (primarily poultry; causes foodborne illness in humans)
Neisseria meningitidis
Gram-negative, Cocci (diplococci), Human (respiratory tract; causes meningitis and sepsis)
Actinomyces spp.
Gram-positive, Rod (filamentous, branching), Human (commensal organism in the mouth and gastrointestinal tract; causes actinomycosis)
Clostridium botulinum
Gram-positive, Rod (anaerobic, spore-forming), Environmental (found in soil, improperly canned food; causes botulism)
Mycoplasma pneumoniae
No cell wall, Pleomorphic (variable shape, often appearing as a fried egg), Human (respiratory tract; causes walking pneumonia)