Bacteria and human health Flashcards

1
Q

How many bacteria compose the human body?

A

40 trillion

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2
Q

What kind of relationship can bacteria and host have?

A

Parasitic
Symbiotic
Free-living

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3
Q

What happens to a newborn?

A

Colonisation.

Newborn is subjected to new bacteria through the environment around it.

The environment around it will therefore affect the microbiota that colonises the body.

There are various different species that compete for the same body surface.

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4
Q

When do communities develop?

A

With age

Depend on the environment of the host

In disease the populations will change

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5
Q

What are the characteristics that alter the parameters of the skin?

A
pH 
Temperature 
Moisture 
Nutrient content 
Shear
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6
Q

What are the characteristics that affect colonization by cutaneous microbes?

A

Temperature
Moisture
Glandular disrtribution
Occlusion of the region

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7
Q

Description of skin

A

Mostly dry
Secretions have high osmolarity
Lipid content changes throughout the body
Temperature changes throughout the body
Temperature is lower than internal organs
Aerobic environment
pH is usually acidic

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8
Q

What is the average amount of sweat produced per day

A

200 ml

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9
Q

What glands produce this sweat

A

Eccrine glands

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10
Q

Where is the bacterial population respectively highest?

A

In the GI tract

The bigger the organ, the larger the bacterial population

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11
Q

What sort of relationship is there between the host and microbiota?

A

Multidirectional chemical communication between host cellular pathways and microbial species/ communities/ activities

Host-microbe metabolic axes

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12
Q

What does the microbiota participate in?

A

Metabolism of food products
Production of growth factors
Protection against infection - colonisation resistance
Stimulation of the immune system

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13
Q

What diseases are related to microbiota dysregulation?

A

Ulcerative colitis
Schizophrenia
Obesity
Autism

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