Bacteria Flashcards
Streptococcus pyogenes resides mostly in what part of the human body?
nasopharynx
strep pharyngitis
Rheumatic fever and glomerulonephritis are a result of untreated__________
Strep A Beta Hemolytic ( strep pyogenes)
(+) test for anginosis species group indicates ?
occult abscessses
What 3 bacteria are implicated in meningitis in neonates?
E/ coli
Listeria Monocytogenes
Group B streptococcus
Which two strains of streptococcus should one immediately assess for ABSCESS?
Strep intermedius
Strep viridans
should order CT scan to evaluate organs
What two streptoccocal strains fall under the non enterococcus classification>
S. Bovis
S. Equinus
What bacteria is associated with increased UTI , cholycystitis and endocarditis acquired in hospital?
(Group D ) Enterococcus faecalis/ faecium
With (+) S. bovis in blood doctor should be aware of possible ______?
colon cancer
Otitis media is caused by what 3 bacteria?
- Strep Pneumoniae
- Haemophilis influezae
- Moraxella catarhalis
Who gets vaccinated for strep pneumoniae?
Elderly folk
immunocompromised
Which staph strains are coagulase negative?
Staph epidermis
Staph saprophyticus
What are the 4 Ds of Botulism
dysphagia
dysphonia
dysarthria
dyplopia
Risus sardonicus is related to which bacterial infection?
Clostiriduim Tetani
Virulence factor: tetanospasmin
Which bacteria is responsible for pseudomembranous enterocolitis?
Clostiridium Dificile (Gram +)
Virulence factor Toxin A/B
What are the symptoms of infant botulism ?
constipation , muscle weaknes, floppy baby
Which non spore forming bacteria infect pediatric patients?
Corynebacterium and Listeria
What gram positive bacteria is/are the most commonly associated with nosocomial infection ?
Group D strep (enterococcus)
Which are the most common organisms associated with prosthetic device infections?
- Staphylococcus epidermis
2. pseudomonas
Which bacteria require infection by a bacteriophage in order to elaborate an active toxin?
Strep A beta hemolytic
Corynebacterium Diptheriae
What bacteria causes necrotizing pneumonia?
Rhodococcus Equi
S. Aureus
Which group of gram negative pathogens cause endocarditis?
HACEK
Haemophilus species Actinobacillus CArdiobacterium Eikenella Kingella
What are the nsocomial (hospital acquired) gram negatives?
E.coli KLebsiella pneumoniae proteus mirabilis Enterobacter serratia Pseudomans aeruginosa
Neisseria can be grown on __________agar and thayer-martin media
chocolate
Neisseria spp. contains __________with strong endotoxin activity
lipopolysaccharide (virulence factor)
Patients with ________ disease and _________patients are at a high risk of infection of Neisseria meningitidis
sickle cell disease
ASPLENIC
The most common cause of meningitis in teenagers is ____________infection
neisseria meningitis
Which 3 bacteria cause similar diarrhea to cholera (rice like stool) and shigella (bloody diarrhea with WBC) ?
E.Coli
Vibrio Cholera
Shigella
__________is the #1 cause of neonatoal meningitis and _________ is 2nd
Group b streptococcus
E.coli
2nd most common nosocomial, gram negative enteric pathogen_________ and 1st is ___________
Klebsiella Pnuemoniae
E.coli
What causes necrotizing pneumonia with currant jelly sputum ?
Klebsiella pneumoniae
virulence factor.: encapsulated (O antigen)
UTI caused by ___________ is characterized by alkaline urine (pH) with an ammonia scent
Proteus mirabilis
Virulence factor: urease
Does Klebsiella ferment lactose?
yes
Klebsiella can result in _______ formation in the lung
asbcess
CAVITARY PNEUMONIA
The three gram negative, lactose fermenters, are major causes of nosocomial infections are …
Klebsiella, Enterobacter and Serratia
ALL FERMENT LACTOSE
What urease positive, pneumonia-causing bacteria is a common cause of UTI?
Klebsiella pneumoniae
Does Shigella ferment lactose?
NO
________causes an c1::inflammatory diarrhea, with the presence of blood and leukocytes
Shigella
virulence factor.: shiga toxin destroys 60 S ribosome
The shiga toxin of Shigella binds the ______subunit of ribosomes, inhibiting protein synthesis
60 S
Which strain of salmonella does not transmit via zoonotic infection?
Salmonella Typhi
Chronic carriers of Salmonella ___________ (species) carry the infection in their _________ (organ)
typhi; gallbladder
Salmonella _______ (species) can present with abdominal pain with _________spots’ cutaneously
typhi ; rose
What cause of osteomyelitis is more common in sickle cell disease patients and asplenic patients?
Salmonella cholerasuis (#1) and S. aureus
A 4-year-old girl presents to her pediatrician for diarrhea and fever. She recently flew back from India, where she spent a summer with her grandparents. She has had a low-grade fever since 3 days prior and had constipation followed by non-bloody diarrhea. On physical exam, she has a low grade fever, abdominal tenderness to palpation, and a faint pink blanching papular rash on her trunk and upper arms. She is started on antibiotics.
What is she being treated for ?
Salmonella Typhi (ROSE SPOTS is described as pink blanching papules
A 43-year-old Caucasian male spent the past month on a business trip in the Caribbean. Two weeks following his return, he began experiencing diarrhea, pain in his abdomen, and a headache. He presents to the hospital and is noted to be febrile with prominent rose-colored spots on his chest and abdomen. Following recovery, the patient may become a carrier of the bacteria with the bacteria heavily localized to the
- spleen
- gallbladder
- neurons
- lungs
- sensory ganglia
- gallbladder
this is salmonella typhi
An 84-year-old female presents to the emergency department from her nursing home with complaints of fever and a productive cough with rust-colored sputum that has developed over the last 2 days. She also endorses shortness of breath and severe fatigue. Her vital signs are as follows: T 38.5 C, RR 18, SpO2 94% on room air. Physical examination is significant for decreased breath sounds and crackles over the the right middle and lower lobes on auscultation. A sputum sample is also collected for gram stain and culture, with the results of the gram stain positive. Which of the following is the primary virulence factor of the infecting pathogen in this patient’s presentation?
- IgA
- M protein
- exotoxin
- polysaccharide capsule
- lipopolysaccharide
This patient is suffering from a Streptococcus pneumoniae pneumonia. The primary virulence factor of S. pneumoniae is its polysaccharide capsule, which inhibits phagocytosis of the pathogen by macrophages or neutrophils.
S. pneumoniae (pneumococcus) is a gram-positive, alpha-hemolytic diplococci that is transmitted by respiratory droplets. It is the most common cause of community acquired pneumonia and meningitis in adults
A 19-year-old college student is brought to the emergency department by her roommate. Her roommate reports that the patient was complaining of a headache this morning. A few hours later, the patient seemed lethargic and confused. In the emergency department, the patient’s vital signs are as follows: HR 98, BP 110/70, T 38.7 degrees Celsius. Her neurological exam is notable for flexion at the hips when her neck is passively flexed. A lumbar puncture is performed, and Gram stain is NEgative. Which of the following bacterial structures does the involved organism use to adhere to the nasopharynx?
- lipooligossacharide
- pilus
- spore
- capsule
- glycocalyx
This patient has meningococcal meningitis, which is cause by Neisseria meningitidis. Neisseria meningitidis uses pili to adhere to epithelial cells in the nasopharynx.
N. meningitidis is a Gram-negative diplococci, which is a common cause of bacterial meningitis in adults, particularly in college students living in dormitories
Which bacteria that causes diarrhea and gastroenteritis cause pseudoappendicitis (RLQ pain)
yersinia enterolitica
Does Vibrio cholera produce an inflammatory diarrhea?
No it causes NON INFLAMMAORY watery rice diarrhea
no WBCS
Which gram-negative enteric bacteria causes rice water stools?
Vibrio cholera
what bacteria would you get if you consume sushi?
vibro parahemolyticus
leading cause of diarrhea in japan
3 most common causes of diarrhea?
ETEC (travelers diarrhea ), camplylobacter jejuni, rotavirus
What bacterial infection is commonly associated with Guillain-Barre syndrome/ reactive arthritis?
Campylobacter jejuni
____________ is an obligate anaerobe that is typically found in the gut and causes abdominal abscesses
Bacterioides fragilis
check after surgeriess
__________ causes necrotizing anaerobic pneumonia following GI aspriation
bacteriodes melaninogenicus
Lung abscesses are commonly due to ANEROBIC bacteria such as Bacteroides, Fusobacterium, and __________________
peptostreptococcus (Gram +)
4 multidrug resistant gram negative bacteria?
pseudomonase.
burkholderia
actinobacter
stephotropomonas
pneumonia in association with cystic fibrosis is due to which bacteria?
burkholderia pseudomonas
not in sketchy
What substances (2) produced by Pseudomonas aeruginosa give it a blue-green pigment?
pyonin / pyocyanin
2 causes of bacterial meningitis LATER in life ?
Hemophilus influenzae
Neisseria Meningitidis
Which cause(s) of painful genital ulceration present with unilateral painful inguinal lymph nodes?
hemophilus ducreyii
A 35-year-old woman presents to the urgent care clinic for genital ulcers. She started having unprotected sexual intercourse with a new partner 1 month ago. She reports that he had not been tested for sexually transmitted diseases. She reports having a painful ulcer on her labia and wishes to be tested.
What are differential diagnoses for this patient?
Soo this person has hemophilus decreyi due to PAINFUL ULCER
differential DX of this is
herpes
syphillis
LGV
A 26-year-old G0 woman with last menstrual period 5 days ago who presents to her gynecologist for fishy-smelling vaginal discharge. She currently has multiple sexual partners and does not use consistent protection. She also requests to be tested for sexually transmitted diseases. On pelvic exam, she has a thin, malodorous gray vaginal discharge that coats the vaginal wall smoothly. Her vulva is not erythematous or edematous. What do you expect to see on wet mount microscopy?
A.. rose spots
b blue cells
c clue cells
d. macrophages
C. this is gardnerella vaginalis
What are the three stages of Bordetella pertussis infection?
Catarrhal (1-2wks pt most contagious
Paroxysmal 2wks - 2ms develops cough
Convalescent (3ms
Legionellla pneumophila is commonly found in ?
air conditiong and cooling towers
What causes Pontiac fever and Legionnairs disease?
Legionellla pneumophila
What are the gram negative bacilli and are all zoonotic?
Yersinia,
Francisella
Brucella
Pasteurella
What is the cause of Bubonic Plague?
Yersinia Pestis
Gram negative ; ROD (bacillis)
Which gram negative bacillus has a bipolar (safety-pin) staining pattern and tends to cause black discoloration
under the skin via hemorrhages?
Yersinia Pestis
Gram negative ; ROD (bacillis)
___________ is a zoonotic bacteria that forms a painful ulcer with a black base at the site of infection
Francicella Tularensis (ulceroglandular tularemia)
(contracted from rabbits , infected ticks or deeerflies
Similar to Yestenia pestis
A 34-year-old man presents to the emergency room for acute-onset fever, pain in the eyes, and ulcer. He has not been to the physician in years, so his past medical history is unknown. He currently works at an angora rabbit farm and interacts with the animals daily. He reports being bit recently on his forearm, where there is now a lesion. On physical exam, he is febrile. He has severe conjunctival injection bilaterally and has multiple 1-2-cm tender cervical lymph nodes.
What is the characteristic gram stain and shape of the bacteria?
Francisella Tularenisis
Gram negative ; ROD (bacillis)
40-year-old woman presents to the emergency room after being bitten by a cat. She cleaned it with some water and soap. On physical exam, she has a normal range of motion and sensation in her thumb. Her pulses are 2+ bilaterally. The wound is irrigated with sterile saline and wound is examined for any foreign bodies
Pt is at risk of contracting?
Pasturella Multocida
Gram negative ; ROD (bacillis)
” CAT chasing a bird in a PASTEUR
Most common STD in the US?
Chlamydia Trachomatis
Leading cause of preventable blindness? What serotype?
Chlamydia Trachomatis (A-C)
NGU or non gonoccal urethritis is caused by what 2 bacteria?
Chlamydia Trachomatis
Ureaplasma Urealyticum
Mycoplasma genitalia
___________can cause reactive arthritis (aka Reiter syndrome
Chlamydia Trachomatis
Campylobacter jejuni