B7.019 Prework: Diffuse Weakness without Numbness

Question 1

motor unit

Answer 1

anterior horn cell
peripheral nerve
neuromuscular junction
muscle fibers

Question 2

signs of motor unit disease

Answer 2

absence of UMN signs
- no hyperreflexia
- no pathological reflexes
- no spasticity
BUT
patients do not necessarily have
-decreased reflexes
-atrophy

Question 3

what type of LMN conditions present w decreased reflexes and atrophy

Answer 3

anterior horn defects

neuron defects

Question 4

what type of LMN conditions can present with preserved reflexes and no atrophy

Answer 4

NMJ disease

muscle disease

Question 5

what clues you in to the lesion being at the nerve level

Answer 5

both sensory and motor involvement peripherally

bilateral, symmetric, LMN type weakness WITH numbness = peripheral neuropathy