B6.5-6 Monoclonal Antibodies And Their Uses

Question 1

How are MAB’s made ?

Answer 1

Lymphocytes make specific antibodies but do not divide are combined with tumour cells that divide
Makes a hybrodoma cell
The cells are cloned
Monoclonal antibodies are made

Question 2

Why are Hybridoma cells made?

Answer 2

Lymphocytes don’t divide but tumours do so it makes clones

Question 3

What are four uses of MAB’s to help treat cancer ?

Answer 3

-Target drugs- carry toxic drugs to stop cancer cells growing but does not damage healthy cells
-Tagging with dyes
-Blocking receptors involved in cell division- stops growth of cells
-Attracting the immune system- recognise, attach and destroy cancer cells

Question 4

What are two other uses of MABs?

Answer 4

Pregnancy tests
HCG, if present it produces a colour change

measuring and monitoring blood hormone levels
Mentors the levels in hormones and tests athletes

Question 5

What are two pros and two cones of MAB’s?

Answer 5

Pros
Can help treat cancer
Harmless production

Cons
Very expensive to develop
Initially created more side effects than expected