B&B: Viral Structure Flashcards
Enveloped
Hep B
Herpes
HIV
Naked
Adenovirus
Rotavirus
Rhinovirus
Hep A/E
All naked viruses are
icosahedral (stable)
Enveloped viruses
icosahedral or helical
Envelope viruses are not transported via
fecal-oral route (requires survival for long period outside body)
Single stranded and linear
Most viruses
ds RNA virus
Reovirus
2 single strands (diploid)
Retroviruses
RNA viruses with circular genome
BAD:
Bunyavirus
Arenavirus
Hep D Virus
RNA viruses that replicate in nucleus
Influenza, Retroviruses
(+) RNA
5’ to 3’
(-) RNA
3’ to 5’
Requires its own RNA polymerase for protein synthesis
Transcription
Make RNA from DNA
DNA-dependent RNA polymerase
Viruses
Make RNA from RNA
Must synthesize their own enzyme
RNA-dependent RNA polymerase
Retroviruses
HIV, HTLV
Retroviruses
2 strand (+) RNA Carry reverse transcriptase enzyme to make dsDNA
Double Stranded
DNA viruses
Single Stranded DNA Virus
Parvo Virus
Viruses with segmented genomes
BOAR: Bunyavirus Orthomyxovirus Arenavirus Reovirus
California, Congo and Hanta are in which family?
Bunyavirus
Influenza is in which family?
Orthomyxovirus
LCMV and Lassa are in which family?
Arenavirus
Rotavirus and Coltivirus are in which family?
Riovirus
Rotavirus causes
diarrhea in kids
B19 virus is the single member of which family?
Parvo Virus
What family is HPV in?
Papilloma
What virus family is JC and BK part of?
Polyoma
What family is HBV in?
Hepadna
HSV, EBC, CMV, VZV, HHV are in what family?
Herpes virus
Small pox, Cow pox, Molluscum Contagiosum are in what family?
Pox virus
Which DNA viruses have a circular DNA structure?
Papilloma
Polyoma
Hepadna
Which DNA virus replicates in cytoplasm?
Pox virus
largest DNA virus
Which DNA virus does not have an icosahedral capsid?
Pox (complex capsid)
All (+) RNA viruses have
Icosahedral capsid (except Corona Virus)
Which (+) RNA virus has a helical capsule?
Corona Virus
All (-) RNA viruses have
helical capsule and are enveloped
All RNA viruses replicate in the cytoplasm except
Influenza and Retroviruses
Live, attenuated vaccines
Small pox, Yellow Fever, VZV, MMR, Intranasal flu
Live, attenuated vaccine for Polio
Sabin’s
Killed virus vaccines
Rabies, IM flu, HAV
Killed virus vaccine for Polio
Salk
Recombinant Vaccine
Immune system will create immune response to injected proteins
Hep B Vaccine
Recombinant proteins of Hep B Surface Antigen
HPV Vaccine
Recombinant proteins of HPV 6, 11, 16 and 18