Autonomic Nervous System Flashcards

1
Q

What does the central nervous system consist of?

A
  • Brain
  • Spinal cord
  • Retina
  • CNII
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2
Q

What does the peripheral nervous system consist of?

A
  • Spinal nerves
  • Cranial nerves (except CNII)
  • Autonomic nervous system (sympathetic and parasympathetic)
  • Somatic sensory and motor nerves
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3
Q

What does the sympathetic nervous system do to:

  • Pupils
  • Heart
  • Blood vessels
  • Gi transit speed
  • Urinary and anal sphincters
  • Bronchi
  • Sweat glands
A
  • Dilate pupils
  • Heart: increase speed and contractility
  • Constrict blood vessels
  • Decrease GI transit speed
  • Dilate bronchi
  • Increase activity of sweat glands
  • Constrict urinary and anal sphincters
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4
Q

What does the parasympathetic nervous system do to:

  • Pupils
  • Heart
  • Bronchi
  • GI transit speed
  • Sphincters
  • Salivary glands
  • Sweat glands
  • Genitals
A
  • Constrict pupils
  • Reduce heart rate and contractility
  • Constrict bronchi
  • Increase GI secretions and transit speed
  • Relaxes sphincters
  • Increases the activity of salivary glands
  • Decreases activity of sweat glands
  • Genitals: sexual arousal
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5
Q

What do spinal nerves contain?

A

Sensory

Motor

Sometimes autonomic fibres

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6
Q

Which spinal nerves contain autonomic nerve fibres?

What can be seen in the spinal cord around these nerves?

A
  • T1-L2
  • S1-S4

Lateral horn can be seen in grey matter

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7
Q

What are the neuro transmitters used in the sympathetic nervous system?

Which receptors do they act on?

What is the exception to this?

A

Preganglionic fibres: Ach (nicotinic receptors)

Postganglionic fibres: Noradrenaline (alpha or beta)

EXCEPT: sweat glands and chromaffin adrenal medulla:

  • ACh activated muscarinic receptors
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8
Q

What neurotransmitters are used in the parasympathetic nervous system?

What receptors do they act on?

A

Preganglionic: ACh (Nicotinic)

Post-ganglionic: ACh (Muscarinic)

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9
Q

At what vertebral level does the spinal cord terminate in an adult?

A
  • L1-L2
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10
Q

Where do sympathetic spinal nerves emerge from the spinal cord?

A

Emerge from the spinal cord only with spinal nerves T1-L2

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11
Q

How does the sympathetic chain communicate with spinal nerves?

A

Via rami communicans

  • White ramus communicans: only found leaving T1-L2 spinal nerves (preganglionic sympathetic neurons passing into the sympathetic chain ganglion)
  • Grey ramus communicans: postganglionic sympathetic fibres passing from the sympathetic ganglia into the spinal nerve
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12
Q

What is Horner’s syndrome?

What are the symptoms?

What can it be caused by?

A

Loss of sympathetic supply to the head:

  • Anhydrosis
  • Ptosis
  • Vasodilation
  • Pupil constriction

Caused by:

  • IV cannulation of internal jugular vein
  • Pancoast tumour of the apex of the lung (compression of sympathetic chain)
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13
Q

What sympathetic chain ganglia are in the neck?

A
  • Superior cervical
  • Middle cervical
  • Stellate (near lung apex)
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14
Q

What do the pre-aortic ganglia supply?

What are they supplied by?

Where are they found?

A

Pre-aortic ganglia are supplied by the splanchnic nerves.

They include:

  • Coeliac (T5-T9) → Foregut
  • Aorticorenal
  • Superior mesenteric (T10-T11) → Midgut
  • Inferior mesenteric (T12-L1) → Hindgut

Found around the blood supply to the gut tube

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15
Q

Describe the sympathetic supply to the gut tube

A

Coeliac ganglion (T5-T9) → Foregut

Aorticorenal ganglion

Superior mesenteric ganglion (T10-T11) → Midgut

Inferior mesenteric ganglion (T12-L1) → Hindgut

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16
Q

Describe the parasympathetic supply to the gut tube

A

Vagus nerve → foregut and midgut

Splanchnic pelvic nerves (S2-S4) → hindgut

17
Q

What is the role of chromaffin cells of the adrenal medulla?

A

Release adrenaline into the blood which provides an additional mechanism for reaching cells or for reaching cells with no sympathetic innervation.

18
Q

Describe the parasympathetic outflow from the CNS

A

4 cranial nerves (brainstem):

  • III
  • VII
  • IX
  • X

3 spinal nerves:

  • S2, 3 & 4
19
Q

What do post-ganglionic parasympathetic neurons of CNIII, VII, IX and X travel with?

A

CNX

20
Q

What is the role of the parasympathetic pelvic splanchnic nerves?

A
  • Relaxation of rectum
  • Constriction of bladder (initiating micturition)
  • Genitals: stimulates sexual arousal
21
Q

What is Frey syndrome? (Frey-Ballinger)

A

Gustatory sweating of the face following parotid surgery/injury due to regrowth of parasympathetic nerves to innervate muscarinic receptors of the sweat glands which are normally sympathetic innervated.