Autominue conditions Exam 6 Flashcards
What is scleroderma?
- It is connect tissue disorder characterized by collagen overproduction
- progressive systemic sclerosis
- Cause is unknown: microvascular abnormalities, irregular collagen
- Physical symptom: immobility, rigifity of skin, inflammation
- Occurs at 30-50 years any age
- 2-5 times more common in FEMALEs
What are some notable changes with scleroderma?
- skin, gastrointestinal tract, kidney, heart muscles, lungs
- eventual death from renal failure , cardiac failure, pulmononary insufficiency, intestinal malabsorption
What are the clinical presentation for scleroderma?
Joints: pain, swelling, stiffness of fingers and knees
* Polyarthritis: symmetrical
* Skin: hard and fixed, ivory- white, yellow or gray
* Face: Mask-like, expressionless
What are the Oral presentation for scleroderma?
Lips: thin, rigid, difficulty opening and closing
* Mucosa: thin, pale, tender, rigid, poor healing
* Gingiva: pale, usually firm
* Teeth: increased mobility
* Radiographic findings: widened PDL
* Mastication: difficult; limited TMJ movement
* Tongue: immobile, speech difficult
What are the medical management for scleroderma?
- Physical therapy
- Maintain normal actvities
What are the dental management for scleroderma?
- Preserve teeth and gingival health
- Prevent extensive treatment
- Dentrue fabrication and wear difficult
- Sensitivity to cold and dampness
What is systemic lupus erythematosus ?
- Immune system attacks its own tissues, causing widespread inflammation and tissue damage to affected organs
- Can also affect joints, skin, brain, lungs, kidneys, and blood vessels.
- Unknown cause
- Possible triggers: infections, stress, diet, toxins, drugs, sunlight
- Affects women 8-10x more than men
Signs and Symptoms: Butterfly or malar rash (across nose and cheeks)
What is the medical management for lupus?
- Same medications as other rheumatologic disorder
- Observation for renal cardiac and clotting issues
- Avoid sun exposure
What is the dental management of
- Consider physician consult to determine patient needs based on disease status at time of appointment
- Review oral side effects of medications
- Possible antibiotic premedication → if taking corticosteroids or cytotoxins and have leukopenia
- Thrombocytopenia → Obtain platelet count for abnormal
bleeding (should be 50,000/mL)
What are the oral manifestations and complications for lupus?
- Lesions on lips and mucosa- red with white spots;
- Possible painful mucosal ulcerations; resemble lichen planus
- Xerostomia
- Hyposalivation
- Dysgeusia
- Glossodynia
What is Sjogrens Syndrome
An immune system disorder characterized by dry eyes and dry mouth. The bodys immune system attacks its own healthy cells that produce saliva and tears
unknown cause
What can sjorgens syndrome lead to?
- Keratoconjunctivitis sicca (dry eyes)
- Xerostomia
- Connective tissue disease
What is the clinical presentation of sjogrens syndrome?
- Dry eyes
- Hyposalivation/xerostomia
- enlarged parotid gland
What is the medical management ?
Medications: Hydroxychloroquine (plaquenil)
Eyes: Cyclosporine
Saliva: Pilocarpine
Immunosuppressives: Methotrexate
NSAIDS
What are the dental management for Sjorgens?
- Focus on palliative and preventive care → relief of symptoms and normal homeostatic environment
- Moisture and lubrication
- Treat conditions → mucositis or candidiasis
- Prevention → OHI, nutritional counseling, importance of frequent recare