Autoantibodies Flashcards
Anti-IgG
Rheumatoid arthritis
Anti- citrullinated protein ab (ACPA)
Rheumatoid arthritis
Anti- centromere
CREST scleroderma
Anti- Scl-70
Diffuse scleroderma
Anti- histone
Drug- induced lupus
Antinuclear antibodies
SLE
Anti- smith
SLE
Andi- dsDNA
Lupus nephritis
Anti- Jo- 1
Polymyositis/ dermatomyositis
Anti- dsDNA
Lupus nephritis
Anti- SSA (anti-Rho)
Sjogren syndrome
Anti- SSB (anti- La)
Sjogren syndrome
Anti- U1- RNP
Mixed connective tissue disease
Anti- desmoglein
Pemphigus vulgaris
Anti- acetylcholine receptor
Myasthenia gravis
Anti- endomysial (anti- tissue transglutaminase)
Celiac disease
Anti- gliadin
Celiac disease
Anti- mitochondrial
Primary biliary cirrhosis
Anti- smooth muscle
Autoimmune hepatitis
Anti- glutamate decarboxylase
Type 1 diabetes
Anti- thyrotropin receptor
Graves Disease
Anti- thyroid peroxidase (anti- TPO)
Hashimoto thyroiditis
Anti- thyroglobulin
Hashimoto thyroiditis/ Graves disease
Anti- basement membrane
Goodpasture syndrome (kidneys, lungs)
c- ANCA (antineutrophil)
Granulomatosis w/ polyangiitis (Wegener)
p-ANCA (cytoplasmic ab)
Pauci- immune crescentic glomerulonephritis
Churg Strauss
Microscopic polyangiitis
DO not give these vaccines to someone w egg all
influenza, yellow fever
Amyloid under a microscope
Congo red stain, apple- green birefringence