Autoantibodies Flashcards

1
Q

Anti-IgG

A

Rheumatoid arthritis

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2
Q

Anti- citrullinated protein ab (ACPA)

A

Rheumatoid arthritis

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3
Q

Anti- centromere

A

CREST scleroderma

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4
Q

Anti- Scl-70

A

Diffuse scleroderma

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5
Q

Anti- histone

A

Drug- induced lupus

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6
Q

Antinuclear antibodies

A

SLE

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7
Q

Anti- smith

A

SLE

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8
Q

Andi- dsDNA

A

Lupus nephritis

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9
Q

Anti- Jo- 1

A

Polymyositis/ dermatomyositis

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10
Q

Anti- dsDNA

A

Lupus nephritis

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11
Q

Anti- SSA (anti-Rho)

A

Sjogren syndrome

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12
Q

Anti- SSB (anti- La)

A

Sjogren syndrome

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13
Q

Anti- U1- RNP

A

Mixed connective tissue disease

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14
Q

Anti- desmoglein

A

Pemphigus vulgaris

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15
Q

Anti- acetylcholine receptor

A

Myasthenia gravis

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16
Q

Anti- endomysial (anti- tissue transglutaminase)

A

Celiac disease

17
Q

Anti- gliadin

A

Celiac disease

18
Q

Anti- mitochondrial

A

Primary biliary cirrhosis

19
Q

Anti- smooth muscle

A

Autoimmune hepatitis

20
Q

Anti- glutamate decarboxylase

A

Type 1 diabetes

21
Q

Anti- thyrotropin receptor

A

Graves Disease

22
Q

Anti- thyroid peroxidase (anti- TPO)

A

Hashimoto thyroiditis

23
Q

Anti- thyroglobulin

A

Hashimoto thyroiditis/ Graves disease

24
Q

Anti- basement membrane

A

Goodpasture syndrome (kidneys, lungs)

25
Q

c- ANCA (antineutrophil)

A

Granulomatosis w/ polyangiitis (Wegener)

26
Q

p-ANCA (cytoplasmic ab)

A

Pauci- immune crescentic glomerulonephritis
Churg Strauss
Microscopic polyangiitis

27
Q

DO not give these vaccines to someone w egg all

A

influenza, yellow fever

28
Q

Amyloid under a microscope

A

Congo red stain, apple- green birefringence