Antidepressants Flashcards
SSRI
blocks serotonin reuptake
fluoxetine sertraline paroxetine citalopram fluvoxamine
SNRI
blocks serotonin and norepinephrine reuptake
venlafaxine
duloxetine
milnacipram
TCA
Blocks 5HT and NE reuptake
imipramine desipramine amitryptyline nortriptyline doxepin
MAOI
inhibits MOA breakdown of NE, DA, 5HT
NDRI
NE, DA reuptake inhibitor Buproprion
Tetracyclic
trazedone
mirtazepine
priapism
trazodone
lowers seizure threshold
buproprion
Works well with SSRIs and increases REM sleep
trazodone
appetite stimulant that is likely to result in weight gain
mirtazapine
can be used for smoking cessation
buproprion
can be used for bedwetting in children
imipramine (TCA)
TCA overdose symptom
convulsions coma cardiotoxicity hyperpyrexia respiratory depression
Serotonin syndrome symptoms
muscle rigidity
hyperthermic CV collapse
Tyramine while on MAOI’s
tyramine accumulates because it is converted to NE due to MAO- inhibition: Hypertensive crisis, hemorrhagic stroke, cardiac arrhythmia